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环境病理学,毒理学和肿瘤学期刊

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ISSN 打印: 0731-8898

ISSN 在线: 2162-6537

The Impact Factor measures the average number of citations received in a particular year by papers published in the journal during the two preceding years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) IF: 2.4 To calculate the five year Impact Factor, citations are counted in 2017 to the previous five years and divided by the source items published in the previous five years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) 5-Year IF: 2.8 The Immediacy Index is the average number of times an article is cited in the year it is published. The journal Immediacy Index indicates how quickly articles in a journal are cited. Immediacy Index: 0.5 The Eigenfactor score, developed by Jevin West and Carl Bergstrom at the University of Washington, is a rating of the total importance of a scientific journal. Journals are rated according to the number of incoming citations, with citations from highly ranked journals weighted to make a larger contribution to the eigenfactor than those from poorly ranked journals. Eigenfactor: 0.00049 The Journal Citation Indicator (JCI) is a single measurement of the field-normalized citation impact of journals in the Web of Science Core Collection across disciplines. The key words here are that the metric is normalized and cross-disciplinary. JCI: 0.59 SJR: 0.429 SNIP: 0.507 CiteScore™:: 3.9 H-Index: 49

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Elucidation of Tumor-Promoting Potential of a Combination Pesticide by Short-Term, In Vivo Bioassay

卷 20, 册 3, 2001, 8 pages
DOI: 10.1615/JEnvironPatholToxicolOncol.v20.i3.70
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摘要

The use of combination pesticide (profenofos 40% + cypermethrin 4% EC) is on the rise in India and elsewhere. Cypermethrin is reported to be a tumor promoter, but its tumor-promoting potential along with profenofos is yet to be studied. A short-term, in vivo test for detection of a tumor promoter is cost-effective, saves time, and requires fewer animals than conventional methods. We report on a short-term test based on mechanisms of significant importance in tumor promotion. In this study, we have tested the tumor-promoting potential of a combination pesticide containing profenofos 40% and cypermethrin 4% EC in Wistar rats. Although cypermethrin has been reported as a tumor promoter, our study shows that the combination pesticide containing profenofos 40% and cypermethrin 4% EC is not a tumor promoter.

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