图书馆订阅: Guest
环境病理学,毒理学和肿瘤学期刊

每年出版 4 

ISSN 打印: 0731-8898

ISSN 在线: 2162-6537

The Impact Factor measures the average number of citations received in a particular year by papers published in the journal during the two preceding years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) IF: 2.4 To calculate the five year Impact Factor, citations are counted in 2017 to the previous five years and divided by the source items published in the previous five years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) 5-Year IF: 2.8 The Immediacy Index is the average number of times an article is cited in the year it is published. The journal Immediacy Index indicates how quickly articles in a journal are cited. Immediacy Index: 0.5 The Eigenfactor score, developed by Jevin West and Carl Bergstrom at the University of Washington, is a rating of the total importance of a scientific journal. Journals are rated according to the number of incoming citations, with citations from highly ranked journals weighted to make a larger contribution to the eigenfactor than those from poorly ranked journals. Eigenfactor: 0.00049 The Journal Citation Indicator (JCI) is a single measurement of the field-normalized citation impact of journals in the Web of Science Core Collection across disciplines. The key words here are that the metric is normalized and cross-disciplinary. JCI: 0.59 SJR: 0.429 SNIP: 0.507 CiteScore™:: 3.9 H-Index: 49

Indexed in

Membrane-Associated MMP-2 in Human Cervical Cancer

卷 22, 册 2, 2003, 8 pages
DOI: 10.1615/JEnvPathToxOncol.v22.i2.20
Get accessGet access

摘要

Matrixmetalloproteinases (MMPs) are a family of secreted or membrane-associated proteins capable of digesting extracellular matrix components. The importance of MMPs in tumor development and invasion is well known. Recent studies have strongly indicated the presence of a functional complex consisting of avb3 integrin, membrane type-1 metalloproteinase-2 (MT1-MMP), and tissue inhibitor of metalloproteinase-2 (TIMP-2) on tumor cell surface, which helps the activation of MMP-2. In this article, we report on the association of active MMP-2 with the membrane fraction of human cervical cancer cells. The association of MMP-2 with avb3 integrin and the expression of membrane type MT1-MMP strongly indicate the role of avb3/MT1-MMP/TIMP-2 complex in the activation of MMP-2 in cervical cancer tissue membrane fraction. The membrane-associated activated MMP-2 may have a role in the migration of tumor cells during invasion.

对本文的引用
  1. Zhang Ying, Qian Haili, Lin Chen, Lang Jinghe, Xiang Yang, Fu Ming, Zhang Xueyan, Liang Xiao, Adenovirus carrying TIMP-3: A potential tool for cervical cancer treatment, Gynecologic Oncology, 108, 1, 2008. Crossref

  2. Marano Grazia, Gronewold Claas, Frank Martin, Merling Anette, Kliem Christian, Sauer Sandra, Wiessler Manfred, Frei Eva, Schwartz-Albiez Reinhard, An easily accessible sulfated saccharide mimetic inhibits in vitro human tumor cell adhesion and angiogenesis of vascular endothelial cells, Beilstein Journal of Organic Chemistry, 8, 2012. Crossref

  3. Damke Gabrielle Marconi Zago Ferreira, Damke Edilson, de Souza Bonfim-Mendonça Patrícia, Ratti Bianca Altrão, de Freitas Meirelles Lyvia Eloiza, da Silva Vânia Ramos Sela, Gonçalves Renato Sonchini, César Gabriel Batista, de Oliveira Silva Sueli, Caetano Wilker, Hioka Noboru, Souza Raquel Pantarotto, Consolaro Marcia Edilaine Lopes, Selective photodynamic effects on cervical cancer cells provided by P123 Pluronic®-based nanoparticles modulating hypericin delivery, Life Sciences, 255, 2020. Crossref

  4. Pandit Anuradha, Begum Yasmin, Saha Priyanka, Srivastava Amit Kumar, Swarnakar Snehasikta, Approaches Toward Targeting Matrix Metalloproteases for Prognosis and Therapies in Gynecological Cancer: MicroRNAs as a Molecular Driver, Frontiers in Oncology, 11, 2022. Crossref

  5. Zhai Yali, Hotary Kevin B., Nan Bin, Bosch F. Xavier, Muñoz Nubia, Weiss Stephen J., Cho Kathleen R., Expression of Membrane Type 1 Matrix Metalloproteinase Is Associated with Cervical Carcinoma Progression and Invasion, Cancer Research, 65, 15, 2005. Crossref

1118 文章浏览量 14 文章下载 统计数据
1118 文章浏览量 14 下载次数 5 Crossref 引用次数 Google
Scholar
引用次数

相似内容的文章:

Binding of a5 Monoclonal Antibody to Cell Surface a5b1 Integrin Modulates MMP-2 and MMP-7 Activity in B16F10 Me Journal of Environmental Pathology, Toxicology and Oncology, Vol.22, 2003, issue 3
Amitava Chatterjee, Jayati Chakrabarti, Aparna Mitra
Cell Membrane-Associated MT1-MMP-Dependent Activation of Pro-MMP-2 in A375 Melanoma Cells Journal of Environmental Pathology, Toxicology and Oncology, Vol.24, 2005, issue 1
Amitava Chatterjee, Jayati Chakrabarti, Aparna Mitra, Aniruddha Banerji
Integrin Modulating Factor: A 30-kD Protein that Modulates the Expression and Function of a5b1 Integrin Receptor Journal of Environmental Pathology, Toxicology and Oncology, Vol.20, 2001, issue 3
Utpal Sanyal, Subrata Ray, Nibedita Chattopadhyay, Amitava Chatterjee, Nupur Biswas
Curcumin Exhibits Antimetastatic Properties by Modulating Integrin Receptors, Collagenase Activity, and Expression of Nm23 and E-Cadherin Journal of Environmental Pathology, Toxicology and Oncology, Vol.22, 2003, issue 1
Subrata Ray, Nibedita Chattopadhyay, Amitava Chatterjee, Maqsood Siddiqi, Aparna Mitra
Effects of Yakuchinone A and Yakuchinone В on the Phorbol Ester-Induced Expression of COX-2 and iNOS and Activation of NF-kB in Mouse Skin Journal of Environmental Pathology, Toxicology and Oncology, Vol.21, 2002, issue 2
Young-Joon Surh, Ok Hee Kim, Jee-Young Kang, Hoil Kang, Kyung-Soo Chun
Begell Digital Portal Begell 数字图书馆 电子图书 期刊 参考文献及会议录 研究收集 订购及政策 Begell House 联系我们 Language English 中文 Русский Português German French Spain