图书馆订阅: Guest
Begell Digital Portal Begell 数字图书馆 电子图书 期刊 参考文献及会议录 研究收集
器官移植长期效应期刊
SJR: 0.145 SNIP: 0.491 CiteScore™: 0.89

ISSN 打印: 1050-6934
ISSN 在线: 1940-4379

器官移植长期效应期刊

DOI: 10.1615/JLongTermEffMedImplants.v18.i4.50
pages 309-319

Looking Ahead: What Long-Term Outcomes Can We Expect from Spinal Devices for Degenerative Disc Disease

Thomas J. Errico
Division of Spine Surgery, Department of Orthopedics, NYU Hospital for Joint Diseases, New York University School of Medicine, New York, New York

ABSTRACT

Degenerative disc disease is one of the leading causes of pain and disability. Various surgical treatments are available, but the literature does not provide a comparative overview of their long-term outcomes. This article synthesizes the available long-term evidence on the treatment of degenerative disc disease. Fusion for degenerative disc disease has recently shown good long-term clinical outcomes, yet several studies strongly suggest that it may accelerate the degenerative process at adjacent levels. Arthroplasty shows at least equivalent long-term outcomes and is not expected to accelerate adjacent degeneration, but speculative concern remains about its safety, especially in regard to wear debris and facet joint arthrosis. Many other treatment devices are in various stages of development, but long-term studies are not yet available for most of them. When making treatment decisions, physicians and patients must consider the long-term outcomes, because the devices remain implanted indefinitely, and back pain could recur at any time if the degeneration progresses or the device fails. Before making a treatment decision, surgeons and patients should thoroughly discuss the long-term clinical prognosis, the safety of various procedures, the degrees of certainty in our currently available medical knowledge, and the patient's preferences. No one solution will be right for every patient, but we are entering a golden era of choices, where most patients with degenerative disc disease should be able to find a treatment that substantially improves their condition.


Articles with similar content:

Temporomandibular Joint Disorders: Artificial Joint Replacements and Future Research Needs
Journal of Long-Term Effects of Medical Implants, Vol.16, 2006, issue 6
Ajay Kashi, Robert W. Christensen
Osteosarcoma Genetics and Epigenetics: Emerging Biology and Candidate Therapies
Critical Reviews™ in Oncogenesis, Vol.20, 2015, issue 3-4
James J. Morrow, Chand Khanna
Advances in Biomaterials for the Treatment of Intervertebral Disc Degeneration
Journal of Long-Term Effects of Medical Implants, Vol.22, 2012, issue 1
Michele Marcolongo, Yakira Kirzner, Sujata K. Bhatia
CAE-Driven Evaluations of Surgical Fixations on Lumbar Spine: An Option for Aiding Ethics in Orthopedics
Ethics in Biology, Engineering and Medicine: An International Journal, Vol.5, 2014, issue 4
Anindya Deb, Malhar N. Kumar, Gunti Ranga Srinivas, Subrata Saha
Management Strategies for Total Hip Arthroplasty in Sickle Cell Patients
Journal of Long-Term Effects of Medical Implants, Vol.24, 2014, issue 2-3
Bartlomiej W. Szczech, Michael A. Mont, Bhaveen V. Kapadia, Yashika D. Patel, Kimona Issa, Sujal Patel