图书馆订阅： Guest
免疫学评论综述™

每年出版 6 期

ISSN 打印: 1040-8401

ISSN 在线: 2162-6472

The Impact Factor measures the average number of citations received in a particular year by papers published in the journal during the two preceding years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) IF: 1.3 To calculate the five year Impact Factor, citations are counted in 2017 to the previous five years and divided by the source items published in the previous five years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) 5-Year IF: 2.6 The Eigenfactor score, developed by Jevin West and Carl Bergstrom at the University of Washington, is a rating of the total importance of a scientific journal. Journals are rated according to the number of incoming citations, with citations from highly ranked journals weighted to make a larger contribution to the eigenfactor than those from poorly ranked journals. Eigenfactor: 0.00079 The Journal Citation Indicator (JCI) is a single measurement of the field-normalized citation impact of journals in the Web of Science Core Collection across disciplines. The key words here are that the metric is normalized and cross-disciplinary. JCI: 0.24 SJR: 0.429 SNIP: 0.287 CiteScore™:: 2.7 H-Index: 81

Indexed in

获得访问权(open in a new tab)
更多的
购买 $35.00(open in a new tab) 检查订阅 下载MARC(open in a new tab) 获取权限(open in a new tab)

New Concepts on the Pathogenesis of Autoimmune Diseases: A Role for Immune Homeostasis, Immunoregulation, and Immunosenescence

卷 28, 册 5, 2008, pp. 363-376
DOI: 10.1615/CritRevImmunol.v28.i5.10
Get accessGet access
Marielle Thewissen
Hasselt University, Biomedical Research Institute and Transnationale Universiteit Limburg, School of Life Sciences, Diepenbeek, Belgium; Maastricht University, Department of Internal Medicine, (CARIM), Maastricht, The Netherlands
Piet Stinissen
Hasselt University, Biomedical Research Institute and Transnationale Universiteit Limburg, School of Life Sciences, Diepenbeek, Belgium

摘要

Complex autoimmune diseases are chronic conditions initiated by a loss of immunological tolerance to self-antigens. Despite many years of intense investigation, the etiopathogenic mechanisms initiating these chronic inflammatory conditions remain undefined. The relatively high prevalence and the clustering of multiple autoimmune diseases within individuals or within families suggest that rather common immune mechanisms may facilitate the development of autoimmune diseases. However, specific genetic or environmental factors seem to be necessary for triggering disease. Clearly, immune mechanisms, which are intended to protect from disease, fail or become dysregulatcd. In this review, we discuss the mechanisms of immune homeostasis, immune regulation, and immunosenescence. We focus on the merit, consequences, and/or shortcomings of these mechanisms and speculate on their possible involvement in autoimmune-disease development.

对本文的引用

  1. Vanheusden Marjan, Stinissen Piet, ’t Hart Bert A., Hellings Niels, Cytomegalovirus: a culprit or protector in multiple sclerosis?, Trends in Molecular Medicine, 21, 1, 2015. Crossref

  2. Tran Tiffany, Paz Pedro, Velichko Sharlene, Cifrese Jill, Belur Praveen, Yamaguchi Ken D., Ku Karin, Mirshahpanah Parham, Reder Anthony T., Croze Ed, Interferonβ-1b Induces the Expression of RGS1 a Negative Regulator of G-Protein Signaling, International Journal of Cell Biology, 2010, 2010. Crossref

  3. Heyduk Ewa, Heyduk Tomasz, Ribosome display enhanced by next generation sequencing: A tool to identify antibody-specific peptide ligands, Analytical Biochemistry, 464, 2014. Crossref

  4. D'Ambrosio Daniele, Tomaselli Valerio, Gargiulo Gaetano, Roselli Mario, Della-Morte David, Abete Pasquale, Evans Syndrome Presented with Marginal Zone Lymphoma and Duodenal Neuroendocrine Tumor in an Elderly Woman, International Journal of Gerontology, 10, 4, 2016. Crossref

  5. Di Sabatino Antonio, Lenti Marco Vincenzo, Giuffrida Paolo, Vanoli Alessandro, Corazza Gino Roberto, New insights into immune mechanisms underlying autoimmune diseases of the gastrointestinal tract, Autoimmunity Reviews, 14, 12, 2015. Crossref

  6. Amariglio Ninette, Klein Adi, Dagan Lana, Lev Atar, Padeh Shai, Rechavi Gideon, Berkun Yackov, Somech Raz, T-Cell Compartment in Synovial Fluid of Pediatric Patients with JIA Correlates with Disease Phenotype, Journal of Clinical Immunology, 31, 6, 2011. Crossref

  7. Costenbader Karen H., Prescott Jennifer, Zee Robert Y., De Vivo Immaculata, Immunosenescence and rheumatoid arthritis: Does telomere shortening predict impending disease?, Autoimmunity Reviews, 10, 9, 2011. Crossref

  8. Gertsch Jürg, Viveros-Paredes Juan Manuel, Taylor Peter, Plant immunostimulants—Scientific paradigm or myth?, Journal of Ethnopharmacology, 136, 3, 2011. Crossref

  9. Dietert Rodney R., Biomarkers of Immunotoxicity, in Biomarkers, 2010. Crossref

  10. Venken Koen, Hellings Niels, Liblau Roland, Stinissen Piet, Disturbed regulatory T cell homeostasis in multiple sclerosis, Trends in Molecular Medicine, 16, 2, 2010. Crossref

  11. Zeher Margit, Papp Gabor, Szodoray Peter, Autologous haemopoietic stem cell transplantation for autoimmune diseases, Expert Opinion on Biological Therapy, 11, 9, 2011. Crossref

  12. Pera Alejandra, Campos Carmen, López Nelson, Hassouneh Fakhri, Alonso Corona, Tarazona Raquel, Solana Rafael, Immunosenescence: Implications for response to infection and vaccination in older people, Maturitas, 82, 1, 2015. Crossref

  13. Haas Jürgen, Korporal Mirjam, Schwarz Alexander, Balint Bettina, Wildemann Brigitte, The interleukin-7 receptor α chain contributes to altered homeostasis of regulatory T cells in multiple sclerosis, European Journal of Immunology, 41, 3, 2011. Crossref

  14. Mason Elizabeth, Tronc Graham, Nones Katia, Matigian Nick, Kim Jinhee, Aronow Bruce J., Wolfinger Russell D., Wells Christine, Gibson Greg, Unutmaz Derya, Maternal Influences on the Transmission of Leukocyte Gene Expression Profiles in Population Samples from Brisbane, Australia, PLoS ONE, 5, 12, 2010. Crossref

  15. Fong Weng Seng, Loh Yvonne, Yoong Jon, Haematopoietic Stem Cell Transplantation in Systemic Lupus Erythematosus: A Case Report and Review of the Literature, Proceedings of Singapore Healthcare, 22, 1, 2013. Crossref

  16. Prescott Jennifer, Karlson Elizabeth W., Orr Esther H., Zee Robert Y.L., De Vivo Immaculata, Costenbader Karen H., A Prospective Study Investigating Prediagnostic Leukocyte Telomere Length and Risk of Developing Rheumatoid Arthritis in Women, The Journal of Rheumatology, 43, 2, 2016. Crossref

  17. Di Sabatino Antonio, Lenti Marco Vincenzo, Corazza Gino Roberto, Neurohumoral Control of Gut Mucosal Defense, in Encyclopedia of Gastroenterology, 2020. Crossref

  18. Xu Weili, Wong Glenn, Hwang You Yi, Larbi Anis, The untwining of immunosenescence and aging, Seminars in Immunopathology, 42, 5, 2020. Crossref

  19. Jakhmola Shweta, Upadhyay Arun, Jain Khushboo, Mishra Amit, Jha Hem Chandra, Herpesviruses and the hidden links to Multiple Sclerosis neuropathology, Journal of Neuroimmunology, 358, 2021. Crossref

  20. Tarjanyi Oktavia, Boldizsar Ferenc, Nemeth Peter, Mikecz Katalin, Glant Tibor T, Age-related changes in arthritis susceptibility and severity in a murine model of rheumatoid arthritis, Immunity & Ageing, 6, 1, 2009. Crossref

  21. Bolton Christopher, An evaluation of the recognised systemic inflammatory biomarkers of chronic sub-optimal inflammation provides evidence for inflammageing (IFA) during multiple sclerosis (MS), Immunity & Ageing, 18, 1, 2021. Crossref

1087 文章浏览量 105 文章下载 统计数据
1087 文章浏览量 105 下载次数 21 Crossref 引用次数 Google
Scholar 引用次数

相似内容的文章:

Autoimmunity in the Peripheral Nervous System Critical Reviews™ in Neurobiology, Vol.15, 2003, issue 1
Bernd C. Kieseier, Stefano C. Previtali, Giancarlo Comi, Hans-Peter Hartung, Angelo Quattrini, Reinhard Kiefer
MHC Genes Linked to Autoimmune Disease Critical Reviews™ in Immunology, Vol.35, 2015, issue 3
Philip Deitiker, M. Zouhair Atassi
Role of Immune Cells in the Initiation and Progression of Pulmonary Fibrosis Critical Reviews™ in Immunology, Vol.42, 2022, issue 5
Joseph Atia Ayariga, Meenakshisundaram Sreepriya, Ganapasam Sudhandiran, Syamala Soumyakrishnan
Cellular Genetics of Host Susceptibility and Resistance to Virus Infection Critical Reviews™ in Eukaryotic Gene Expression, Vol.16, 2006, issue 2
H. Earl Ruley, Donald H. Rubin
Dimethyl Fumarate Modulation of Immune and Antioxidant Responses: Application to HIV Therapy Critical Reviews™ in Immunology, Vol.33, 2013, issue 4
Alexander J. Gill , Dennis L. Kolson

最新一期

The Value of Systemic Immune-Inflammation Index and T Cell Subsets in the Severity and Prognosis of Sepsis Hao Zhou MiRNA let-7d-5p Alleviates Inflammatory Responses by Targeting Map3k1 and Inactivating ERK/p38 MAPK Signaling in Microglia Fan Fang, Cheng Chen Mechanistic Insights into Tanshinone IIA in the Amelioration of Post-Thyroidectomy Hypoparathyroidism Xiaoyu Qian, Lin Li, Liang Chen, Chao Shen, Jian Tang Effect of the p-Estrogen Receptor at Serine on Its Function and Breast Growth Yuan Liang, Junhui Qin, Tiancheng Ma, Tong Yang, Zhenyu Ke, Ruian Wang

将发表的论文

Identification of key chondrocyte apoptosis-related genes in osteoarthritis based on weighted gene co-expression network analysis and experimental verification Wei Wang, Junyi Hong, Tianyi Cao, Fusheng Ye, Junwei Gao, Shumei Qin Anoikis and Mitophagy-Related Gene Signature for Predicting the Survival and Tumor Cell Progression in Colon Cancer Jian Shen, Minzhe Li Exploring the mechanism of Isoforskolin against asthma based on network pharmacology and experimental verification Yan Fang, Shibo Sun, Chuang Xiao, Min Li, Yuanyuan Zheng, Anju Zu, Zhuang Luo Identification of a novel five-gene prognostic model for laryngeal cancer associated with mitophagy using integrated bioinformatics analysis and experimental verification Dong Song, Lun Dong, Mei Wang, Xiaoping Gao Function of steroid receptor coactivators (SRCs) in T cells and cancers: Implications for cancer immunotherapy Wencan Zhang, Xu Cao, Hongmin Wu, Xiancai Zhong, Yun Shi, Zuoming Sun Electroacupuncture Alleviates Ischemic Stroke by Activating the mTOR/SREBP1 Pathway Jiawang Lang, Jianchang Luo, Luodan Wang, Wenbin Xu, Jie Jia, Zhipeng Zhao, Boxu Lang KIAA1429 induces the m6A modification of LINC01106 to enhance the malignancy of lung adenocarcinoma cell via JAK/STAT3 pathway Di Xu, Ziming Wang, Fajiu Li Effects of different doses of dexmedetomidine on the prevention of postoperative sleep disturbance and serum neurotransmitter level in patients under general anesthesia Huifei Lu, Fei He, Ying Huang, Zhongliang Wei
Begell Digital Portal Begell 数字图书馆 电子图书 期刊 参考文献及会议录 研究收集 订购及政策 Begell House 联系我们 Language English 中文 Русский Português German French Spain