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ISSN 打印: 0893-9675

ISSN 在线: 2162-6448

SJR: 0.395 SNIP: 0.322 CiteScore™:: 2.5 H-Index: 54

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Review of the GAS3 Family of Proteins and their Relevance to Cancer

卷 20, 册 5-6, 2015, pp. 435-447
DOI: 10.1615/CritRevOncog.v20.i5-6.140
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摘要

The GAS3 family of tetraspan proteins has recently been implicated in the progression of cancer. Currently, six members of the GAS3 family have been identified in humans and mice, and while their expressions in disease vary, data suggest that they play a role in epithelial cell structure and function. In this review, we highlight the studies implicating four of the members in disease pathogenesis as well as probe the structural similarities between the family members. Finally, the impact of targeting select members of the family such as PMP22 and EMP2 is discussed.

对本文的引用
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  7. Kawaguchi Miku, Kawao Naoyuki, Muratani Masafumi, Takafuji Yoshimasa, Ishida Masayoshi, Kinoshita Yuko, Takada Yuto, Mizukami Yuya, Ohira Takashi, Kaji Hiroshi, Role of peripheral myelin protein 22 in chronic exercise‐induced interactions of muscle and bone in mice, Journal of Cellular Physiology, 237, 5, 2022. Crossref

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