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多孔介质期刊
影响因子: 1.49 5年影响因子: 1.159 SJR: 0.43 SNIP: 0.671 CiteScore™: 1.58

ISSN 打印: 1091-028X
ISSN 在线: 1934-0508

多孔介质期刊

DOI: 10.1615/JPorMedia.v9.i2.30
pages 127-134

Soft Tissue Responses and Attachment to Porous Titanium with Different Surface Characteristics

Yao Wu
Engineering Research Center in Biomaterials, Sichuan University, Chengdu 610064, P.R. China
Hu Li
Engineering Research Center in Biomaterials, Sichuan University, Chengdu 610064, P.R. China
Tun Yuan
Engineering Research Center in Biomaterials, Sichuan University, Chengdu 610064, P.R. China
Chunlin Deng
Engineering Research Center in Biomaterials, Sichuan University, Chengdu 610064, P.R. China
Bangcheng Yang
Engineering Research Center in Biomaterials, Sichuan University, Chengdu 610064, P.R. China
Xingdong Zhang
Engineering Research Center in Biomaterials, Sichuan University, Chengdu 610064, P.R. China

ABSTRACT

In this paper, soft tissue responses and attachment strength to porous titanium scaffolds with suitable surface microstructures were studied as a comparison of with and without bonelike apatite on the surface. All of the samples were implanted subcutaneously into the backs of rabbits (n = 7). Forty days and seventy days postoperation, the samples with the surrounding tissues were harvested, respectively. Some of them were used for immediate biomechanical attachment testing and the others for histological observations. Following mechanical testing, the received cross sections were analyzed with scanning electron microscopy with X-ray energy dispersion spectroscopy (SEM-EDX) in order to view the attachment of the tissues to different surfaces. The results showed that the attachment strength of all samples increased with time. The strength of porous titanium coated by bonelike apatite was higher than that of the uncoated one, and the interface integration of the materials/tissue was also better than that of the uncoated sample at both implantation periods.