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等离子医学
SJR: 0.278 SNIP: 0.183 CiteScore™: 0.57

ISSN 打印: 1947-5764
ISSN 在线: 1947-5772

等离子医学

DOI: 10.1615/PlasmaMed.v1.i1.70
pages 85-92

Plasma-Controlled Cell Migration: Localization of Cold Plasma−Cell Interaction Region

Olga Volotskova
School of Engineering and Applied Sciences, Department of Mechanical and Aerospace Engineering, George Washington University, USA
Alexey Shashurin
The George Washington University; School of Aeronautics and Astronautics, Purdue University, West Lafayette, IN, USA
M. A. Stepp
School of Medicine and Health Sciences, George Washington University, USA
S. Pal-Ghosh
School of Medicine and Health Sciences, George Washington University, USA
Michael Keidar
Department of Mechanical and Aerospace Engineering, The George Washington University, Science and Engineering Hall, 800 22nd Street, NW, Room 3550, Washington, DC 20052, USA

ABSTRACT

In order to characterize the optimal condition for cell treatment with a plasma jet, its UV-vis-NIR spectrum was evaluated. Furthermore, this study considers the ability of cold atmospheric plasmas to impact cell migration rates as a function of (i) the length of the plasma treatment time, (ii) the number of hours after treatment that cell migration is assessed, and (iii) localization of the treatment zone. Data show that the ability of plasma to reduce cell migration rates increases as a function of treatment time with a maximum of 30%, and that this affect persists for 33 hours after plasma treatment.