图书馆订阅: Guest
Begell Digital Portal Begell 数字图书馆 电子图书 期刊 参考文献及会议录 研究收集
等离子医学
SJR: 0.198 SNIP: 0.183 CiteScore™: 0.57

ISSN 打印: 1947-5764
ISSN 在线: 1947-5772

等离子医学

DOI: 10.1615/PlasmaMed.2014011904
pages 29-36

Effect of Active Radical Production on Plasma Degradation of Phorbol 12-Myristate 13-Acetate in Methanolic and Aqueous Solution

Hiroto Matsuura
Osaka Prefecture University
Y. Onishi
Osaka Prefecture University, Gakuen-cho 1-2, Sakai Naka-ku, 599-8570, Japan;
S. Kongmany
Osaka Prefecture University, Gakuen-cho 1-2, Sakai Naka-ku, 599-8570, Japan; National University of Laos, Vientiane Capital, 7322, Lao PDR
Y. Maeda
Osaka Prefecture University, Gakuen-cho 1-2, Sakai Naka-ku, 599-8570, Japan;
M. Furuta
Osaka Prefecture University, Gakuen-cho 1-2, Sakai Naka-ku, 599-8570, Japan;
K. Imamura
Osaka Prefecture University, Gakuen-cho 1-2, Sakai Naka-ku, 599-8570, Japan;
S. Okuda
Osaka Prefecture University, Gakuen-cho 1-2, Sakai Naka-ku, 599-8570, Japan;

ABSTRACT

In this study, we examine the degradation of phorbol esters with atmospheric pressure plasma and, in particular, the highly tolerant phorbol 12-myristate 13-acetate (PMA) molecule. We determined the degradation mechanism by analyzing the structural information of the by-product obtained using mass spectrometry. The plasma source was also improved to generate more active radicals, thereby enhancing the degradation of PMA.