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Osteoclasts Have Multiple Roles in Bone in Addition to Bone Resorption

卷 19, 册 3, 2009, pp. 171-180
DOI: 10.1615/CritRevEukarGeneExpr.v19.i3.10
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摘要

Osteoclasts are the cells that degrade bone to initiate normal bone remodeling and mediate bone loss in pathologic conditions by increasing their resorptive activity. They are derived from precursors in the myeloid/ monocyte lineage that circulate in the blood after their formation in the bone marrow. These osteoclast precursors (OCPs) are attracted to sites on bone surfaces destined for resorption and fuse with one another to form the multinucleated cells that resorb calcified matrixes under the influence of osteoblastic cells in bone marrow. Recent studies have identified functions for OCPs and osteoclasts in and around bone other than bone resorption. For example, they regulate the differentiation of osteoblast precursors and the movement of hematopoietic stem cells from the bone marrow to the bloodstream; they participate in immune responses, and secrete cytokines that can affect their own functions and those of other cells in inflammatory and neoplastic processes affecting bone. Here, we review these findings, which define new roles for osteoclasts and OCPs in the growing field of osteoimmunology and in common pathologic conditions in which bone resorption is increased.

对本文的引用
  1. Ross F. Patrick, Osteoclasts, in Vitamin D, 2011. Crossref

  2. Boyce Brendan F., Rosenberg Elizabeth, de Papp Anne E., Duong Le T., The osteoclast, bone remodelling and treatment of metabolic bone disease, European Journal of Clinical Investigation, 42, 12, 2012. Crossref

  3. Boyce Brendan, Xing Lianping, Src inhibitors in the treatment of metastatic bone disease: rationale and clinical data, Clinical Investigation, 1, 12, 2011. Crossref

  4. Kim Jung-Lye, Kang Min-Kyung, Gong Ju-Hyun, Park Sin-Hye, Han Seon-Young, Kang Young-Hee, Novel antiosteoclastogenic activity of phloretin antagonizing RANKL-induced osteoclast differentiation of murine macrophages, Molecular Nutrition & Food Research, 56, 8, 2012. Crossref

  5. Boyce Brendan F., Zuscik Michael J., Xing Lianping, Biology of Bone and Cartilage, in Genetics of Bone Biology and Skeletal Disease, 2013. Crossref

  6. Lerner Ulf H., Osteoblasts, Osteoclasts, and Osteocytes: Unveiling Their Intimate-Associated Responses to Applied Orthodontic Forces, Seminars in Orthodontics, 18, 4, 2012. Crossref

  7. Brzóska Malgorzata M., Rogalska Joanna, Kupraszewicz Elżbieta, The involvement of oxidative stress in the mechanisms of damaging cadmium action in bone tissue: A study in a rat model of moderate and relatively high human exposure, Toxicology and Applied Pharmacology, 250, 3, 2011. Crossref

  8. Yu Xiaohua, Wang Liping, Peng Fei, Jiang Xi, Xia Zengmin, Huang Jianping, Rowe David, Wei Mei, The effect of fresh bone marrow cells on reconstruction of mouse calvarial defect combined with calvarial osteoprogenitor cells and collagen-apatite scaffold, Journal of Tissue Engineering and Regenerative Medicine, 7, 12, 2013. Crossref

  9. Boyce Brendan F, Advances in osteoclast biology reveal potential new drug targets and new roles for osteoclasts, Journal of Bone and Mineral Research, 28, 4, 2013. Crossref

  10. Zimmer Gerald, Rohrhofer Astrid, Lewis Kanthi, Goessl Andreas, Hoffmann Oskar, The surface microporosity of ceramic biomaterials influences the resorption capacity of osteoclasts, Journal of Biomedical Materials Research Part A, 101, 12, 2013. Crossref

  11. Chen Zetao, Wu Chengtie, Yuen Jones, Klein Travis, Crawford Ross, Xiao Yin, Influence of osteocytes in thein vitroandin vivoβ-tricalcium phosphate-stimulated osteogenesis, Journal of Biomedical Materials Research Part A, 102, 8, 2014. Crossref

  12. Mediero Aránzazu, Perez-Aso Miguel, Cronstein Bruce N, Activation of adenosine A2Areceptor reduces osteoclast formation via PKA- and ERK1/2-mediated suppression of NFκB nuclear translocation, British Journal of Pharmacology, 169, 6, 2013. Crossref

  13. Devlin Maureen J, Cloutier Alison M, Thomas Nishina A, Panus David A, Lotinun Sutada, Pinz Ilka, Baron Roland, Rosen Clifford J, Bouxsein Mary L, Caloric restriction leads to high marrow adiposity and low bone mass in growing mice, Journal of Bone and Mineral Research, 25, 9, 2010. Crossref

  14. Fu Ying-Xiao, Gu Jian-Hong, Zhang Yi-Ran, Tong Xi-Shuai, Zhao Hong-Yan, Yuan Yan, Liu Xue-Zhong, Bian Jian-Chun, Liu Zong-Ping, Inhibitory effects of osteoprotegerin on osteoclast formation and function under serum-free conditions, Journal of Veterinary Science, 14, 4, 2013. Crossref

  15. Zhang Xin-Wen, Zhou Chun, Zhu Han-Dong, Shao Weiwei, You Yan, Peng Jin, Yin Sheng, Shen Xiaoyan, Inhibition of osteoclastogenesis by 6-[10′(Z)-heptadecenyl] salicylic acid from Syzygium tetragonum Wall via preventing nuclear translocation of NFATc1, Phytomedicine, 21, 7, 2014. Crossref

  16. Boyce Rogely W., Varela Aurore, Chouinard Luc, Bussiere Jeanine L., Chellman Gary J., Ominsky Michael S., Pyrah Ian T., Infant cynomolgus monkeys exposed to denosumab in utero exhibit an osteoclast-poor osteopetrotic-like skeletal phenotype at birth and in the early postnatal period, Bone, 64, 2014. Crossref

  17. Goker-Alpan Ozlem, Therapeutic approaches to bone pathology in Gaucher disease: Past, present and future, Molecular Genetics and Metabolism, 104, 4, 2011. Crossref

  18. Marcucci Gemma, Zimran Ari, Bembi Bruno, Kanis John, Reginster Jean-Yves, Rizzoli Renè, Cooper Cyrus, Brandi Maria Luisa, Gaucher Disease and Bone Manifestations, Calcified Tissue International, 95, 6, 2014. Crossref

  19. Buenrostro Denise, Park Serk In, Sterling Julie A., Dissecting the Role of Bone Marrow Stromal Cells on Bone Metastases, BioMed Research International, 2014, 2014. Crossref

  20. de Vries Teun J., Schoenmaker Ton, Aerts David, Grevers Lilyanne C., Souza Pedro P.C., Nazmi Kamran, van de Wiel Mark A., Ylstra Bauke, van Lent Peter L., Leenen Pieter J.M., Everts Vincent, M-CSF Priming of Osteoclast Precursors Can Cause Osteoclastogenesis-Insensitivity, Which Can be Prevented and Overcome on Bone, Journal of Cellular Physiology, 230, 1, 2015. Crossref

  21. Balkhi Mumtaz Yaseen, Ahmad Shazia, Guttridge Denis C., MicroRNA Function in Muscle Homeostasis and Regenerative Medicine, in MicroRNA in Regenerative Medicine, 2015. Crossref

  22. Sobhia Masilamani Elizabeth, Paul Stanly, Shinde Ranajit, Potluri Mrudula, Gundam Venkatesh, Kaur Amandeep, Haokip Thongtinlal, Protein tyrosine phosphatase inhibitors: a patent review (2002 – 2011), Expert Opinion on Therapeutic Patents, 22, 2, 2012. Crossref

  23. Kwan Ping, Osteoporosis: From osteoscience to neuroscience and beyond, Mechanisms of Ageing and Development, 145, 2015. Crossref

  24. Heckt Timo, Keller Johannes, Reusch Roswitha, Hartmann Kristin, Krasemann Susanne, Hermans-Borgmeyer Irm, Amling Michael, Schinke Thorsten, No obvious phenotypic abnormalities in mice lacking the Pate4 gene, Biochemical and Biophysical Research Communications, 469, 4, 2016. Crossref

  25. Shandala Tetyana, Shen Ng Yeap, Hopwood Blair, Yip Yuen-Ching, Foster Bruce K., Xian Cory J., The role of osteocyte apoptosis in cancer chemotherapy-induced bone loss, Journal of Cellular Physiology, 227, 7, 2012. Crossref

  26. Masi L., Agnusdei D., Bilezikian J., Chappard D., Chapurlat R., Cianferotti L., Devolgelaer J.-P., El Maghraoui A., Ferrari S., Javaid M. K., Kaufman J.-M., Liberman U. A., Lyritis G., Miller P., Napoli N., Roldan E., Papapoulos S., Watts N. B., Brandi M. L., Taxonomy of rare genetic metabolic bone disorders, Osteoporosis International, 26, 10, 2015. Crossref

  27. Mahoney David J., Swales Catherine, Athanasou Nicholas A., Bombardieri Michele, Pitzalis Costantino, Kliskey Karolina, Sharif Mohammed, Day Anthony J., Milner Caroline M., Sabokbar Afsie, TSG-6 inhibits osteoclast activity via an autocrine mechanism and is functionally synergistic with osteoprotegerin, Arthritis & Rheumatism, 63, 4, 2011. Crossref

  28. Truman Jean-Philip, Al Gadban Mohammed M., Smith Kent J., Hammad Samar M., Acid sphingomyelinase in macrophage biology, Cellular and Molecular Life Sciences, 68, 20, 2011. Crossref

  29. Sharaf-Eldin Wessam E., Abu-Shahba Nourhan, Mahmoud Marwa, El-Badri Nagwa, The Modulatory Effects of Mesenchymal Stem Cells on Osteoclastogenesis, Stem Cells International, 2016, 2016. Crossref

  30. Peruzzi Barbara, Teti Anna, The Physiology and Pathophysiology of the Osteoclast, Clinical Reviews in Bone and Mineral Metabolism, 10, 2, 2012. Crossref

  31. Metz J. R., de Vrieze E., Lock E.-J., Schulten I. E., Flik G., Elasmoid scales of fishes as model in biomedical bone research, Journal of Applied Ichthyology, 28, 3, 2012. Crossref

  32. Liao Xiaoling, Lu Shaoying, Zhuo Yue, Winter Christina, Xu Wenfeng, Li Bo, Wang Yingxiao, Bone Physiology, Biomaterial and the Effect of Mechanical/Physical Microenvironment on Mesenchymal Stem Cell Osteogenesis, Cellular and Molecular Bioengineering, 4, 4, 2011. Crossref

  33. Boyce Brendan F, Wnt5a non-canonical signaling through Ror2; a novel co-stimulatory mechanism to enhance RANKL-induced osteoclastogenesis, IBMS BoneKEy, 9, 2012. Crossref

  34. Samadfam Rana, Awori Malaika, Bénardeau Agnes, Bauss Frieder, Sebokova Elena, Wright Matthew, Smith Susan Y, Combination treatment with pioglitazone and fenofibrate attenuates pioglitazone-mediated acceleration of bone loss in ovariectomized rats, Journal of Endocrinology, 212, 2, 2012. Crossref

  35. Jansen Ineke D. C., Vermeer Jenny A. F., Bloemen Veerle, Stap Jan, Everts Vincent, Osteoclast Fusion and Fission, Calcified Tissue International, 90, 6, 2012. Crossref

  36. Sher Roger B., Cox Gregory A., Ackert-Bicknell Cheryl, Development and Disease of Mouse Muscular and Skeletal Systems, in The Laboratory Mouse, 2012. Crossref

  37. Lorenzo Joseph A, Do osteoclasts have dual roles: Bone resorption and antigen presentation?, IBMS BoneKEy, 8, 1, 2011. Crossref

  38. Díaz-Castro Javier, Kajarabille Naroa, Pulido-Morán Mario, Moreno-Fernández Jorge, López-Frías Magdalena, Ochoa Julio J., Influence of Omega-3 Fatty Acids on Bone Turnover, in Omega-3 Fatty Acids, 2016. Crossref

  39. Kang In Soon, Kim Chaekyun, NADPH oxidase gp91phox contributes to RANKL-induced osteoclast differentiation by upregulating NFATc1, Scientific Reports, 6, 1, 2016. Crossref

  40. Nam Diane, Mau Elaine, Wang Yufa, Wright David, Silkstone David, Whetstone Heather, Whyne Cari, Alman Benjamin, Frey Oliver, T-Lymphocytes Enable Osteoblast Maturation via IL-17F during the Early Phase of Fracture Repair, PLoS ONE, 7, 6, 2012. Crossref

  41. Reynaert Niki L., Gopal Poornima, Rutten Erica P.A., Wouters Emiel F.M., Schalkwijk Casper G., Advanced glycation end products and their receptor in age-related, non-communicable chronic inflammatory diseases; Overview of clinical evidence and potential contributions to disease, The International Journal of Biochemistry & Cell Biology, 81, 2016. Crossref

  42. Garner Sanford, Anderson John, Skeletal Tissues and Mineralization, in Diet, Nutrients, and Bone Health, 2011. Crossref

  43. Fiorino Cara, Harrison Rene E., E-cadherin is important for cell differentiation during osteoclastogenesis, Bone, 86, 2016. Crossref

  44. Boskey A.L., Coleman R., Aging and Bone, Journal of Dental Research, 89, 12, 2010. Crossref

  45. Boyce Brendan F., Zuscik Michael J., Xing Lianping, Biology of Bone and Cartilage, in Genetics of Bone Biology and Skeletal Disease, 2018. Crossref

  46. Rezende Eloiza, Bradaschia-Correa Vivian, Siviero Fabio, Ambrosio Lucas M. B., Arana-Chavez Victor E., Effects of bisphosphonates on osteogenesis and osteoclastogenesis signaling during the endochondral ossification of growing rats, Cell and Tissue Research, 368, 2, 2017. Crossref

  47. Nie Chun-Hong, Wan Shi-Ming, Tomljanovic Tea, Treer Tomislav, Hsiao Chung-Der, Wang Wei-Min, Gao Ze-Xia, Comparative proteomics analysis of teleost intermuscular bones and ribs provides insight into their development, BMC Genomics, 18, 1, 2017. Crossref

  48. Diaz-Castro Javier, Alférez Maria J.M., Moreno-Fernandez Jorge, López-Aliaga Inmaculada, Influence of Goat Milk on Bone and Mineral Metabolism During Iron Deficiency Recovery, in Nutrients in Dairy and their Implications on Health and Disease, 2017. Crossref

  49. Boyce B.F., Advances in the Regulation of Osteoclasts and Osteoclast Functions, Journal of Dental Research, 92, 10, 2013. Crossref

  50. Sang Chenglin, Zhang Jiefeng, Zhang Yongxian, Chen Fangjing, Cao Xuecheng, Guo Lei, TNF-α promotes osteoclastogenesis through JNK signaling-dependent induction of Semaphorin3D expression in estrogen-deficiency induced osteoporosis, Journal of Cellular Physiology, 232, 12, 2017. Crossref

  51. Alessandrini Federica, Pezzè Laura, Ciribilli Yari, LAMPs: Shedding light on cancer biology, Seminars in Oncology, 44, 4, 2017. Crossref

  52. Doak Geneva R., Schwertfeger Kathryn L., Wood David K., Distant Relations: Macrophage Functions in the Metastatic Niche, Trends in Cancer, 4, 6, 2018. Crossref

  53. De-La-Cruz-Montoya Aldo H., Ramírez-Salazar Eric G., Martínez-Aguilar Mayeli M., González-de-la-Rosa Pablo M., Quiterio Manuel, Abreu-Goodger Cei, Salmerón Jorge, Velázquez-Cruz Rafael, Identification of miR-708-5p in peripheral blood monocytes: Potential marker for postmenopausal osteoporosis in Mexican-Mestizo population, Experimental Biology and Medicine, 243, 13, 2018. Crossref

  54. Hu Zi’ang, Chen Yilei, Song Lijiang, Yik Jasper H. N., Haudenschild Dominik R., Fan Shunwu, Flavopiridol Protects Bone Tissue by Attenuating RANKL Induced Osteoclast Formation, Frontiers in Pharmacology, 9, 2018. Crossref

  55. Madel Maria-Bernadette, Ibáñez Lidia, Wakkach Abdelilah, de Vries Teun J., Teti Anna, Apparailly Florence, Blin-Wakkach Claudine, Immune Function and Diversity of Osteoclasts in Normal and Pathological Conditions, Frontiers in Immunology, 10, 2019. Crossref

  56. Kang In Soon, Kim Chaekyun, Taurine Chloramine Inhibits Osteoclastic Differentiation and Osteoclast Marker Expression in RAW 264.7 Cells, in Taurine 11, 1155, 2019. Crossref

  57. Hall Brian K., Eckhard Witten P., Plasticity and Variation of Skeletal Cells and Tissues and the Evolutionary Development of Actinopterygian Fishes, in Evolution and Development of Fishes, 2018. Crossref

  58. Wieszczycka Karolina, Staszak Katarzyna, Woźniak-Budych Marta J., Jurga Stefan, Lanthanides and tissue engineering strategies for bone regeneration, Coordination Chemistry Reviews, 388, 2019. Crossref

  59. de Vries Teun J., Huesa Carmen, The Osteocyte as a Novel Key Player in Understanding Periodontitis Through its Expression of RANKL and Sclerostin: a Review, Current Osteoporosis Reports, 17, 3, 2019. Crossref

  60. Burya A. E., Kirgizov K. I., Pristanskova E. A., Melnikova M. B., Palm V. V., Mikhailova S. V., Skorobogatova E. V., Practice of allogeneic hematopoietic stem cell transplantation for infantile autosomal recessive osteopetrosis, Pediatric Hematology/Oncology and Immunopathology, 18, 2, 2019. Crossref

  61. Sourial Maryanne, Coco Maria, Bone Health in Women with Chronic Kidney Disease, in Obstetric and Gynecologic Nephrology, 2020. Crossref

  62. de Vries Teun J., Schoenmaker Ton, van Veen Henk A., Hogervorst Jolanda, Krawczyk Przemek M., Moonen Carolyn G. J., Jansen Ineke D. C., The Challenge of Teaching Essential Immunology Laboratory Skills to Undergraduates in One Month—Experience of an Osteoimmunology Course on TLR Activation, Frontiers in Immunology, 10, 2019. Crossref

  63. Ponzetti Marco, Rucci Nadia, Updates on Osteoimmunology: What's New on the Cross-Talk Between Bone and Immune System, Frontiers in Endocrinology, 10, 2019. Crossref

  64. de Vries Teun J., el Bakkali Ismail, Kamradt Thomas, Schett Georg, Jansen Ineke D. C., D'Amelio Patrizia, What Are the Peripheral Blood Determinants for Increased Osteoclast Formation in the Various Inflammatory Diseases Associated With Bone Loss?, Frontiers in Immunology, 10, 2019. Crossref

  65. Shahen V.A., Gerbaix M., Koeppenkastrop S., Lim S.F., McFarlane K.E., Nguyen Amanda N.L., Peng X.Y., Weiss N.B., Brennan-Speranza T.C., Multifactorial effects of hyperglycaemia, hyperinsulinemia and inflammation on bone remodelling in type 2 diabetes mellitus, Cytokine & Growth Factor Reviews, 55, 2020. Crossref

  66. Wong Sok Kuan, Chin Kok-Yong, Ima-Nirwana Soelaiman, The Skeletal-Protecting Action and Mechanisms of Action for Mood-Stabilizing Drug Lithium Chloride: Current Evidence and Future Potential Research Areas, Frontiers in Pharmacology, 11, 2020. Crossref

  67. Zhi Xin, Chen Qian, Song Shaojun, Gu Zhengrong, Wei Wenqiang, Chen Huiwen, Chen Xiao, Weng Weizong, Zhou Qirong, Cui Jin, Cao Liehu, Myostatin Promotes Osteoclastogenesis by Regulating Ccdc50 Gene Expression and RANKL-Induced NF-κB and MAPK Pathways, Frontiers in Pharmacology, 11, 2020. Crossref

  68. Piccoli Alessandra, Cannata Francesca, Strollo Rocky, Pedone Claudio, Leanza Giulia, Russo Fabrizio, Greto Valentina, Isgrò Camilla, Quattrocchi Carlo Cosimo, Massaroni Carlo, Silvestri Sergio, Vadalà Gianluca, Bisogno Tiziana, Denaro Vincenzo, Pozzilli Paolo, Tang Simon Y, Silva Matt J, Conte Caterina, Papalia Rocco, Maccarrone Mauro, Napoli Nicola, Sclerostin Regulation, Microarchitecture, and Advanced Glycation End‐Products in the Bone of Elderly Women With Type 2 Diabetes, Journal of Bone and Mineral Research, 35, 12, 2020. Crossref

  69. Lim Soomin, Kim Tae Hoon, Ihn Hye Jung, Lim Jiwon, Kim Gi-Young, Choi Yung Hyun, Bae Jong-Sup, Jung Jae-Chang, Shin Hong-In, Kim Jung-Eun, Park Eui Kyun, Inhibitory effect of oolonghomobisflavan B on osteoclastogenesis by suppressing p38 MAPK activation, Bioorganic & Medicinal Chemistry Letters, 30, 18, 2020. Crossref

  70. San Miguel Jose E., Holton Kenneth J., Polly David W., Anatomy and Physiology/Biology of Bone, in Revision Lumbar Spine Surgery, 2022. Crossref

  71. Xu Xia, Liu Shuyu, Liu Hua, Ru Kang, Jia Yunxian, Wu Zixiang, Liang Shujing, Khan Zarnaz, Chen Zhihao, Qian Airong, Hu Lifang, Piezo Channels: Awesome Mechanosensitive Structures in Cellular Mechanotransduction and Their Role in Bone, International Journal of Molecular Sciences, 22, 12, 2021. Crossref

  72. Belenska-Todorova Lyudmila, Zhivkova Ralitsa, Markova Maya, Ivanovska Nina, Follicle stimulating hormone and estradiol alter immune response in osteoarthritic mice in an opposite manner, International Journal of Immunopathology and Pharmacology, 35, 2021. Crossref

  73. Munasinghe Aravinda, Lin Ping, Colina Coray M., Unraveling Binding Interactions between Human RANKL and Its Decoy Receptor Osteoprotegerin, The Journal of Physical Chemistry B, 121, 39, 2017. Crossref

  74. Ping Jianfeng, Zhou Chao, Dong Yongqiang, Wu Xudong, Huang Xiaogang, Sun Bin, Zeng Bin, Xu Fangming, Liang Wenqing, Modulating immune microenvironment during bone repair using biomaterials: Focusing on the role of macrophages, Molecular Immunology, 138, 2021. Crossref

  75. Woźniczka Magdalena, Błaszczak-Świątkiewicz Katarzyna, New Generation of Meso and Antiprogestins (SPRMs) into the Osteoporosis Approach, Molecules, 26, 21, 2021. Crossref

  76. Anani Tareq, Castillo Alesha B., Mechanically-regulated bone repair, Bone, 154, 2022. Crossref

  77. Umi Partan Radiyati, Hidayat Rachmat, The relationship between TNF-α gene polymorphism, pro-inflammatory cytokines and bone turnover markers in COPD patients with osteoporosis, Journal of Physics: Conference Series, 1246, 1, 2019. Crossref

  78. Hamie Lamiaa, Abbas Ossama, Kurban Mazen, Bhawan Jag, Osteoclast-Like Giant Cells: Focus on Entities Relevant to Dermatopathology and Underlying Pathogenesis, The American Journal of Dermatopathology, 43, 3, 2021. Crossref

  79. Dolzhenko A., Richter T., Sagalovsky S., VASCULAR CALCIFICATION, ATHEROSCLEROSIS AND BONE LOSS (OSTEOPOROSIS): NEW PATHOPHYSIOLOGICAL MECHANISMS AND FUTURE PERSPECTIVES FOR PHARMACOLOGICAL THERAPY, Almanac of Clinical Medicine, 44, 4, 2016. Crossref

  80. Chamani Sajad, Liberale Luca, Mobasheri Leila, Montecucco Fabrizio, Al‐Rasadi Khalid, Jamialahmadi Tannaz, Sahebkar Amirhossein, The role of statins in the differentiation and function of bone cells, European Journal of Clinical Investigation, 51, 7, 2021. Crossref

  81. Ramesh Priyanka, Jagadeesan Rahul, Sekaran Saravanan, Dhanasekaran Anuradha, Vimalraj Selvaraj, Flavonoids: Classification, Function, and Molecular Mechanisms Involved in Bone Remodelling, Frontiers in Endocrinology, 12, 2021. Crossref

  82. e Silva Edney P., Huang Boyang, Helaehil Júlia V., Nalesso Paulo R. L., Bagne Leonardo, de Oliveira Maraiara A., Albiazetti Gabriela C. C., Aldalbahi Ali, El-Newehy Mohamed, Santamaria-Jr Milton, Mendonça Fernanda A. S., Bártolo Paulo, Caetano Guilherme F., In vivo study of conductive 3D printed PCL/MWCNTs scaffolds with electrical stimulation for bone tissue engineering, Bio-Design and Manufacturing, 4, 2, 2021. Crossref

  83. Jerome Christopher P., Boyce Rogely, Bone Therapeutics: Safety Considerations, Session Summary, Toxicologic Pathology, 45, 7, 2017. Crossref

  84. Giuffrida Gaetano, Cingari Maria Rocca, Parrinello Nunziatina, Romano Alessandra, Triolo Anna, Franceschino Magda, Di Raimondo Francesco, Bone Turnover Markers in Patients with Type 1 Gaucher Disease, Hematology Reports, 4, 4, 2012. Crossref

  85. Witten P.E., Harris M.P., Huysseune A., Winkler C., Small teleost fish provide new insights into human skeletal diseases, in The Zebrafish - Disease Models and Chemical Screens, 138, 2017. Crossref

  86. Anatomy and physiology of bone, in Pathology of Bone and Joint Disorders, 2014. Crossref

  87. Kayalar Emre, Goger Fatih, Tas Deynek Gul, Tok Olgu Enis, Kucuk Sevim, New bone-generative effect of Salvia officinalis L. in the expanded midpalatal suture, Journal of Orofacial Orthopedics / Fortschritte der Kieferorthopädie, 2022. Crossref

  88. Akasaka Tsukasa, Tamai Miho, Yoshimura Yoshitaka, Ushijima Natsumi, Numamoto Shinichiro, Yokoyama Atsuro, Miyaji Hirofumi, Takata Ryo, Yamagata Shuichi, Sato Yoshiaki, Nakanishi Ko, Yoshida Yasuhiro, Different micro/nano-scale patterns of surface materials influence osteoclastogenesis and actin structure, Nano Research, 15, 5, 2022. Crossref

  89. Dong Chenbin, Liu Xiangqi, Li Jun, Lan Dongyi, Zheng Shan, Dysregulation of the HOTAIR-miR-152-CAMKIIα Axis in Craniosynostosis Results in Impaired Osteoclast Differentiation, Frontiers in Genetics, 13, 2022. Crossref

  90. Guo Jiahua, Ito Shohei, Nguyen Hoa Thanh, Yamamoto Kimika, Iwata Hisato, Effects on the hepatic transcriptome of chicken embryos in ovo exposed to phenobarbital, Ecotoxicology and Environmental Safety, 160, 2018. Crossref

  91. Suh Kwang Sik, Chon Suk, Jung Woon-Won, Choi Eun Mi, Effects of methylglyoxal on RANKL-induced osteoclast differentiation in RAW264.7 cells, Chemico-Biological Interactions, 296, 2018. Crossref

  92. Melke Johanna, Midha Swati, Ghosh Sourabh, Ito Keita, Hofmann Sandra, Silk fibroin as biomaterial for bone tissue engineering, Acta Biomaterialia, 31, 2016. Crossref

  93. Herroon M K, Rajagurubandara E, Rudy D L, Chalasani A, Hardaway A L, Podgorski I, Macrophage cathepsin K promotes prostate tumor progression in bone, Oncogene, 32, 12, 2013. Crossref

  94. Berretta Massimiliano, Quagliariello Vincenzo, Bignucolo Alessia, Facchini Sergio, Maurea Nicola, Di Francia Raffaele, Fiorica Francesco, Sharifi Saman, Bressan Silvia, Richter Sara N., Camozzi Valentina, Rinaldi Luca, Scaroni Carla, Montopoli Monica, The Multiple Effects of Vitamin D against Chronic Diseases: From Reduction of Lipid Peroxidation to Updated Evidence from Clinical Studies, Antioxidants, 11, 6, 2022. Crossref

  95. Khalaf Omar H., Chaki Sankar P., Garcia-Gonzalez Daniel G., Suva Larry J., Gaddy Dana, Arenas-Gamboa Angela M., Roy Craig R., Interaction of Brucella abortus with Osteoclasts: a Step toward Understanding Osteoarticular Brucellosis and Vaccine Safety, Infection and Immunity, 88, 4, 2020. Crossref

  96. Ji Ling, Li Xinyi, He Shushu, Chen Song, Regulation of osteoclast-mediated bone resorption by microRNA, Cellular and Molecular Life Sciences, 79, 6, 2022. Crossref

  97. de Vrieze Erik, Sharif Faiza, Metz Juriaan R., Flik Gert, Richardson Michael K., Matrix metalloproteinases in osteoclasts of ontogenetic and regenerating zebrafish scales, Bone, 48, 4, 2011. Crossref

  98. Suh Kwang Sik, Chon Suk, Jung Woon-Won, Choi Eun Mi, Effect of bergenin on RANKL-induced osteoclast differentiation in the presence of methylglyoxal, Toxicology in Vitro, 61, 2019. Crossref

  99. Elson Ari, Anuj Anuj, Barnea-Zohar Maayan, Reuven Nina, The origins and formation of bone-resorbing osteoclasts, Bone, 164, 2022. Crossref

  100. Newman Hunter, Hoque Jiaul, Shih Yu-Ru V., Marushack Gabrielle, Ko Unghyeon, Gonzales Gavin, Varghese Shyni, pH-Sensitive nanocarrier assisted delivery of adenosine to treat osteoporotic bone loss, Biomaterials Science, 10, 18, 2022. Crossref

  101. Radzki Radoslaw Piotr, Bienko Marek, Wolski Dariusz, Oniszczuk Tomasz, Radzka-Pogoda Agnieszka, Polak Pawel, Borzecki Andrzej, Stasiak Mateusz, Lipoic acid (LA) dose-dependently protects bone losses in the mandible of rats during the development of osteopenia by inhibiting oxidative stress and promoting bone formation, Biomedicine & Pharmacotherapy, 146, 2022. Crossref

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