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ISSN 打印: 1045-4403

ISSN 在线: 2162-6502

The Impact Factor measures the average number of citations received in a particular year by papers published in the journal during the two preceding years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) IF: 1.6 To calculate the five year Impact Factor, citations are counted in 2017 to the previous five years and divided by the source items published in the previous five years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) 5-Year IF: 2.2 The Immediacy Index is the average number of times an article is cited in the year it is published. The journal Immediacy Index indicates how quickly articles in a journal are cited. Immediacy Index: 0.3 The Eigenfactor score, developed by Jevin West and Carl Bergstrom at the University of Washington, is a rating of the total importance of a scientific journal. Journals are rated according to the number of incoming citations, with citations from highly ranked journals weighted to make a larger contribution to the eigenfactor than those from poorly ranked journals. Eigenfactor: 0.00058 The Journal Citation Indicator (JCI) is a single measurement of the field-normalized citation impact of journals in the Web of Science Core Collection across disciplines. The key words here are that the metric is normalized and cross-disciplinary. JCI: 0.33 SJR: 0.345 SNIP: 0.46 CiteScore™:: 2.5 H-Index: 67

Indexed in

Vitamin D Control of Gene Expression: Temporal and Spatial Parameters for Organization of the Regulatory Machinery

卷 18, 册 2, 2008, pp. 163-172
DOI: 10.1615/CritRevEukarGeneExpr.v18.i2.50
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摘要

Vitamin D is a principal modulator of skeletal gene expression, thus necessitating an understanding of interfaces between the activity of this steroid hormone and regulatory cascades that are functionally linked to the regulation of skeletal genes. Physiologic responsiveness requires combinatorial control, whereas coregulatory proteins determine the specificity of biologic responsiveness to physiologic cues. It is becoming increasingly evident that regulatory complexes containing the vitamin D receptor are dynamic rather than static. Temporal and spatial modifications in the composition of these complexes provide a mechanism for integrating regulatory signals to support positive or negative control through synergism and antagonism. Compartmentalization of components of vitamin D control in nuclear microenvironments supports the integration of regulatory activities, perhaps by establishing thresholds for protein activity in time frames that are consistent with the execution of regulatory signaling.

对本文的引用
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  2. Lian Jane B., Gravallese Ellen M., Stein Gary S., Osteoblasts and their Signaling Pathways, in Osteoimmunology, 2011. Crossref

  3. Ynsa M. D., Dang Z. Y., Manso-Silvan M., Song J., Azimi S., Wu J. F., Liang H. D., Torres-Costa V., Punzon-Quijorna E., Breese M. B. H., Garcia-Ruiz J. P., Reprogramming hMSCs morphology with silicon/porous silicon geometric micro-patterns, Biomedical Microdevices, 16, 2, 2014. Crossref

  4. Zhang Ying, Hassan Mohammad Q., Li Zhao-Yong, Stein Janet L., Lian Jane B., van Wijnen Andre J., Stein Gary S., Intricate gene regulatory networks of helix-loop-helix (HLH) proteins support regulation of bone-tissue related genes during osteoblast differentiation, Journal of Cellular Biochemistry, 105, 2, 2008. Crossref

  5. Scalabrino Giuseppe, Vitamin-regulated cytokines and growth factors in the CNS and elsewhere, Journal of Neurochemistry, 111, 6, 2009. Crossref

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