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ISSN 打印: 1045-4403

ISSN 在线: 2162-6502

The Impact Factor measures the average number of citations received in a particular year by papers published in the journal during the two preceding years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) IF: 1.6 To calculate the five year Impact Factor, citations are counted in 2017 to the previous five years and divided by the source items published in the previous five years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) 5-Year IF: 2.2 The Immediacy Index is the average number of times an article is cited in the year it is published. The journal Immediacy Index indicates how quickly articles in a journal are cited. Immediacy Index: 0.3 The Eigenfactor score, developed by Jevin West and Carl Bergstrom at the University of Washington, is a rating of the total importance of a scientific journal. Journals are rated according to the number of incoming citations, with citations from highly ranked journals weighted to make a larger contribution to the eigenfactor than those from poorly ranked journals. Eigenfactor: 0.00058 The Journal Citation Indicator (JCI) is a single measurement of the field-normalized citation impact of journals in the Web of Science Core Collection across disciplines. The key words here are that the metric is normalized and cross-disciplinary. JCI: 0.33 SJR: 0.345 SNIP: 0.46 CiteScore™:: 2.5 H-Index: 67

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Association between HIF1α 1772 C/T Polymorphism and Breast Cancer Susceptibility: A Systematic Review

卷 27, 册 4, 2017, pp. 297-304
DOI: 10.1615/CritRevEukaryotGeneExpr.2017019947
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摘要

Studies have reached conflicting conclusions about the association of the 1772 C/T polymorphism in the hypoxia-inducible factor 1α (HIF1α) gene with breast cancer risk. To address this, we performed a meta-analysis of relevant studies in the included literature. Data were collected from the electronic databases PubMed and EMBase. The association was assessed by determination of the odds ratio (OR) and the corresponding 95% confidence interval (95% CI). A total of seven articles involving 2343 cases and 2246 controls were analyzed in our meta-analysis. Overall, we found no significant association between the HIF1α C1772T polymorphism and breast cancer (TT vs. CC: OR = 1.33, 95% CI = 0.49-3.63; CT vs. CC: OR = 1.07, 95% CI = 0.90–1.27; dominant model: OR = 1.10, 95% CI = 0.93–1.30; recessive model: OR = 1.32, 95% CI = 0.50–3.49). In stratified analysis by ethnic group, a statistically significant association was observed in Asians. Our findings demonstrated that the 1772 C/T polymorphism in the HIF1α gene might be a risk factor for the development of breast cancer in Asians.

对本文的引用
  1. Zhang Zhi, Sun Liwei, Zhang Yixuan, Lu Guanming, Li Yongqiang, Wei Zhongheng, Long non‐coding RNA FEZF1‐AS1 promotes breast cancer stemness and tumorigenesis via targeting miR‐30a/Nanog axis, Journal of Cellular Physiology, 233, 11, 2018. Crossref

  2. Kancharla Jyothsna, Dariya Begum, Momin Saimila, Prasad Immadisetty Devi Vara, Bhaskar L.V.K.S., Bramhachari Pallaval Veera, Alam Afroz, HIF1A C1772T genetic variation is associated with the elevated risk of breast cancer among Asians: An updated meta-analysis, Meta Gene, 25, 2020. Crossref

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  4. Jiang Ming , Qiu Ni , Xia Haoming , Liang Hongling , Li Hongsheng , Ao Xiang , Long non‑coding RNA FOXD2‑AS1/miR‑150‑5p/PFN2 axis regulates breast cancer malignancy and tumorigenesis, International Journal of Oncology, 2019. Crossref

  5. Sookaromdee Pathum, Wiwanitkti Viroj, Association of hypoxia-inducible factor-1α polymorphisms with susceptibility to nonsmall-cell lung cancer: A summative analysis, Journal of Cancer Research and Therapeutics, 17, 4, 2021. Crossref

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