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真核基因表达评论综述™
影响因子: 1.841 5年影响因子: 1.927 SJR: 0.649 SNIP: 0.516 CiteScore™: 1.96

ISSN 打印: 1045-4403
ISSN 在线: 2162-6502

真核基因表达评论综述™

DOI: 10.1615/CritRevEukaryotGeneExpr.2018020088
pages 17-24

Critical Review on Curcumin as a Therapeutic Agent: From Traditional Herbal Medicine to an Ideal Therapeutic Agent

Muhammad Usman Akbar
Department of Pharmaceutical Chemistry, Government College University Faisalabad, Pakistan; Department of Applied Chemistry, Government College University Faisalabad, Pakistan
Kanwal Rehman
Department of Pharmacy, University of Agriculture, Faisalabad, Pakistan
Khalid Mahmood Zia
Department of Applied Chemistry, Government College University Faisalabad, Pakistan
Muhammad Imran Qadir
Institute of Molecular Biology and Biotechnology, Bahauddin Zakariya University, Bosan Road, Multan, Pakistan
Muhammad Sajid Hamid Akash
Department of Pharmaceutical Chemistry, Government College University Faisalabad, Pakistan
Muhammad Ibrahim
Department of Applied Chemistry, Government College University Faisalabad, Pakistan

ABSTRACT

Traditionally, many natural medicinal plants have been used to treat a variety of diseases since ancient times and are considered a potential source of phytochemicals for the development of new drugs. One of these is curcumin, which is an easily accessible, inexpensive, and nontoxic bioactive compound. Curcumin is a very important, naturally occurring, and highly lipophilic and phenolic substance derived from the rhizomes of plant Curcuma longa, a member of the Zingiberaceae (ginger) family, which is mostly used as a curry spice, flavoring agent, insect repellent, coloring agent in food, traditional drug, and ingredient in cosmetics. Modern scientific research has demonstrated that it has wide range of pharmacological activities and medicinal properties against various types of diseases, disorders, and syndromes. Because it has been known for many years to have excellent therapeutic potential against various diseases, much research has been devoted to this natural product. This review briefly summarizes the scope, therapeutic potential and clinical applications of curcumin.