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ISSN 打印: 1045-4403

ISSN 在线: 2162-6502

The Impact Factor measures the average number of citations received in a particular year by papers published in the journal during the two preceding years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) IF: 1.6 To calculate the five year Impact Factor, citations are counted in 2017 to the previous five years and divided by the source items published in the previous five years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) 5-Year IF: 2.2 The Immediacy Index is the average number of times an article is cited in the year it is published. The journal Immediacy Index indicates how quickly articles in a journal are cited. Immediacy Index: 0.3 The Eigenfactor score, developed by Jevin West and Carl Bergstrom at the University of Washington, is a rating of the total importance of a scientific journal. Journals are rated according to the number of incoming citations, with citations from highly ranked journals weighted to make a larger contribution to the eigenfactor than those from poorly ranked journals. Eigenfactor: 0.00058 The Journal Citation Indicator (JCI) is a single measurement of the field-normalized citation impact of journals in the Web of Science Core Collection across disciplines. The key words here are that the metric is normalized and cross-disciplinary. JCI: 0.33 SJR: 0.345 SNIP: 0.46 CiteScore™:: 2.5 H-Index: 67

Indexed in

Response of Osteoblasts to the Stimulus of Fluid Flow

卷 25, 册 2, 2015, pp. 153-162
DOI: 10.1615/CritRevEukaryotGeneExpr.2015013564
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摘要

Bone is an important porous tissue that supports the body, maintains calcium and phosphate homeostasis, protects vital organs, and houses bone marrow. The interaction between hydrostatic pressure and fluid phase, solid phase, cells, and vascular in bone makes bone inevitably bear baseline levels of fluid flow. Fluid flow plays an important role in regulating the proliferation, differentiation, distribution, and apoptosis of osteoblasts in bone. The effect of fluid flow on osteoblasts is dependent on time, velocity, and type. Some response of osteoblasts to fluid flow is closely related to the soluble factors secreted by the osteoblasts themselves or other types of bone cells. When the response is disordered, related bone diseases such as osteoporosis, osteoarthritis, and abnormal osteogenesis probably happen. In this article we review the current progress in the study of the response of osteoblasts to the direct and indirect stimulus of fluid flow and their roles in osteogenesis and related bone diseases.

对本文的引用
  1. Lyons James S., Iyer Shama R., Lovering Richard M., Ward Christopher W., Stains Joseph P., Novel multi-functional fluid flow device for studying cellular mechanotransduction, Journal of Biomechanics, 49, 16, 2016. Crossref

  2. Huang Wanyue, Wang Peiyan, Shen Tongtong, Hu Chongwei, Han Yanfei, Song Miao, Bian Yu, Li Yanfei, Zhu Yanzhu, Aluminum Trichloride Inhibited Osteoblastic Proliferation and Downregulated the Wnt/β-Catenin Pathway, Biological Trace Element Research, 177, 2, 2017. Crossref

  3. Huang Lingwei, Korhonen Rami K., Turunen Mikael J., Finnilä Mikko A.J., Experimental mechanical strain measurement of tissues, PeerJ, 7, 2019. Crossref

  4. Alfieri Roberta, Vassalli Massimo, Viti Federica, Flow-induced mechanotransduction in skeletal cells, Biophysical Reviews, 11, 5, 2019. Crossref

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