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生物,工程和医学的道德

ISSN 打印: 2151-805X

ISSN 在线: 2151-8068

SJR: 0.123

Crossing the Germline Barrier: The Three Genome Baby

卷 6, 册 3-4, 2015, pp. 237-261
DOI: 10.1615/EthicsBiologyEngMed.2016016331
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摘要

The moral boundary separating somatic cell genetic modification and germline genetic modification has been in effect for over 30 years. Recently, with the introduction of nuclear DNA transplantation and gene editing, and with the rising interest in preventing the transfer of certain deleterious genes to newborns, that moral boundary has been called into question. The paper discusses the origins of the somatic cell and germline moral distinction and explores new initiatives to undertake genetic modification of gametes or embryos.

对本文的引用
  1. Cussins Jessica, Lowthorp Leah, Germline Modification and Policymaking: The Relationship between Mitochondrial Replacement and Gene Editing, The New Bioethics, 24, 1, 2018. Crossref

  2. Krimsky Sheldon, Breaking the germline barrier in a moral vacuum, Accountability in Research, 26, 6, 2019. Crossref

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