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生物,工程和医学的道德
SJR: 0.123

ISSN 打印: 2151-805X
ISSN 在线: 2151-8068

生物,工程和医学的道德

DOI: 10.1615/EthicsBiologyEngMed.2016016331
pages 237-261

Crossing the Germline Barrier: The Three Genome Baby

Sheldon Krimsky
Lenore Stern Professor of Humanities & Social Sciences, Tufts University, Medford, MA

ABSTRACT

The moral boundary separating somatic cell genetic modification and germline genetic modification has been in effect for over 30 years. Recently, with the introduction of nuclear DNA transplantation and gene editing, and with the rising interest in preventing the transfer of certain deleterious genes to newborns, that moral boundary has been called into question. The paper discusses the origins of the somatic cell and germline moral distinction and explores new initiatives to undertake genetic modification of gametes or embryos.


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