图书馆订阅: Guest
Begell Digital Portal Begell 数字图书馆 电子图书 期刊 参考文献及会议录 研究收集
国际药用蘑菇期刊
影响因子: 1.423 5年影响因子: 1.525 SJR: 0.433 SNIP: 0.661 CiteScore™: 1.38

ISSN 打印: 1521-9437
ISSN 在线: 1940-4344

国际药用蘑菇期刊

DOI: 10.1615/IntJMedMushr.v6.i3.10
24 pages

Medicinal Value of Turkey Tail Fungus Trametes versicolor (L.:Fr.) Pilát (Aphyllophoromycetideae). A Literature Review

Christopher Hobbs
Institute for Natural Products Research, Davis, CA 95065; and Institute for Natural Products Research, 4731 East Fork Rd., Williams, OR 97544, USA

ABSTRACT

Trametes (=Coriolus) versicolor (L.:Fr.) Pilát, is a small, flexible polypore fungus that is an important part of the forest ecology as a recycler of dead and dying trees in forests throughout the world. Of all the mushrooms used today for their medicinal qualities, more research has been performed on this species than any other, including shiitake (Lentinus edodes), or reishi (Ganoderma lucidum).High-molecular-weight fractions from the mycelium have been studied in human clinical trials, especially polysaccharide Krestin (PSK), which is an approved drug paid for by national health care in Japan. PSK is given orally (often 3 grams/day), along with several chemotherapy protocols. Numerous in vitro and in vivo studies show enhancement of immune functions, antiviral effects, and cholesterol-regulating effects, among others. New clinical trials demonstrate improved quality of life after surgery and in combination with chemotherapy, as well as extended 5- and 10-year survival rates, especially for patients with colorectal and stomach cancers. Further studies are needed in order to clarify the most effective forms of the whole fruiting body extracts, mycelium extracts, and their high-molecular weight fractions, along with the optimum dose. Safety issues, while not completely determined for long-term treatment, during pregnancy, or in combination with pharmaceutical drugs, seem to be of low concern, with no noted published side effects or interactions with drugs reported.


Articles with similar content:

Medicinal Value of Turkey Tail Fungus Trametes versicolor (L.:Fr.) Pilat (Aphyllophoromycetideae)
International Journal of Medicinal Mushrooms, Vol.7, 2005, issue 3
Christopher Hobbs
Chemopreventive and Tumoricidal Properties of Ling Zhi Mushroom Ganoderma lucidum (W. Curt.:Fr.) Lloyd (Aphyllophoromycetideae). Part I. Preclinical and Clinical Studies (Review)
International Journal of Medicinal Mushrooms, Vol.6, 2004, issue 2
He Gao, Jin Lan, Yihuai Gao, Wenbo Tank, Shufeng Zhou
Medicinal Mushrooms in Human Clinical Studies. Part I. Anticancer, Oncoimmunological, and Immunomodulatory Activities: A Review
International Journal of Medicinal Mushrooms, Vol.19, 2017, issue 4
Solomon P. Wasser
Screening Systems for Medicinal Basidiomycetes Antitumor Extracts
International Journal of Medicinal Mushrooms, Vol.7, 2005, issue 3
Anatoliy I. Usov, Elena B. Isakova, Anastasia V. Avtonomova, Larissa M. Krasnopolskaya, Igor V. Belitsky, Vladimir M. Bukhman, N. Soboleva, Alex Libenzon
Medicinal Value of Lentinus edodes (Berk.) Sing. (Agaricomycetideae). A Literature Review
International Journal of Medicinal Mushrooms, Vol.2, 2000, issue 4
Christopher Hobbs