每年出版 12 期
ISSN 打印: 1521-9437
ISSN 在线: 1940-4344
Indexed in
Anti-Inflammatory Effects of Extracts from the Medicinal Mushrooms Hypsizygus marmoreus and Pleurotus eryngii (Agaricomycetes)
摘要
The inflammatory response caused by the immune system can be defensive, but a long-term inflammatory response may lead to the development of many different chronic diseases. In this study, 4 extracts were prepared from Hypsizygus marmoreus and Pleurotus eryngii fruiting bodies and used to evaluate their effects on inflammation-related mediators in RAW 264.7 cells. The 4 extracts contained substantial amounts of phenolic compounds (5.10-9.96 mg/g extract) and flavonoids (1.92-5.13 mg/g extract). With the extracts added, the production of nitric oxide and the proinflammatory interleukin (IL)-6 could be effectively suppressed, whereas the production of the proinflammatory tumor necrosis factor-α and IL-1Β could be relatively suppressed. In addition, production of the anti-inflammatory cytokine IL-10 could be increased. Overall, these mushrooms might be capable of amending inflammatory responses.
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Mleczek Mirosław, Siwulski Marek, Rzymski Piotr, Budka Anna, Kalač Pavel, Jasińska Agnieszka, Gąsecka Monika, Budzyńska Sylwia, Niedzielski Przemysław, Comparison of elemental composition of mushroom Hypsizygus marmoreus originating from commercial production and experimental cultivation, Scientia Horticulturae, 236, 2018. Crossref
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Anusiya G, Gowthama Prabu U, Yamini N V, Sivarajasekar N, Rambabu K, Bharath G, Banat Fawzi, A review of the therapeutic and biological effects of edible and wild mushrooms, Bioengineered, 12, 2, 2021. Crossref