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ISSN 在线: 1940-4344

The Impact Factor measures the average number of citations received in a particular year by papers published in the journal during the two preceding years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) IF: 1.2 To calculate the five year Impact Factor, citations are counted in 2017 to the previous five years and divided by the source items published in the previous five years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) 5-Year IF: 1.4 The Immediacy Index is the average number of times an article is cited in the year it is published. The journal Immediacy Index indicates how quickly articles in a journal are cited. Immediacy Index: 0.3 The Eigenfactor score, developed by Jevin West and Carl Bergstrom at the University of Washington, is a rating of the total importance of a scientific journal. Journals are rated according to the number of incoming citations, with citations from highly ranked journals weighted to make a larger contribution to the eigenfactor than those from poorly ranked journals. Eigenfactor: 0.00066 The Journal Citation Indicator (JCI) is a single measurement of the field-normalized citation impact of journals in the Web of Science Core Collection across disciplines. The key words here are that the metric is normalized and cross-disciplinary. JCI: 0.34 SJR: 0.274 SNIP: 0.41 CiteScore™:: 2.8 H-Index: 37

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Antimicrobial and Cytotoxic Activities of the Sulphur Shelf Medicinal Mushroom, Laetiporus sulphureus (Agaricomycetes), from Serbia

卷 18, 册 6, 2016, pp. 469-476
DOI: 10.1615/IntJMedMushrooms.v18.i6.10
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摘要

Cyclohexane, dichloromethane, and methanol extracts of the medicinal mushroom Laetiporus sulphureus were tested for their antimicrobial, cytotoxic, and radical scavenging activities. Total polyphenol content was also determined. Regarding the amount of the phenolic compounds in the methanol extract, there were 14.1 ± 0.6 mg gallic acid/g dry extract and a concentration of 0.66 ±0.15 mg/mL resulted in the removal of 50% of the DPPH radicals (half-maximal inhibitory concentration [IC50]) . The average minimum inhibitory concentrations (MICs) against a select panel of microorganisms were between 125 and 250 μg/mL, and the methanolic extract significantly inhibited the growth of Staphylococcus aureus (MIC, 31.25 μg/mL). Also, cyclohexane and dichloromethane extracts inhibited the growth of Helicobacter pylori (MIC, 62.5 μg/mL). Cyclohexane and dichloromethane extracts showed higher antiproliferative action compared with the methanol extract. The lowest IC50 was induced on HeLa cells by dichloromethane extract (IC50,67.20 ± 5.49 μg/mL), followed by cyclohexane extract (IC50 75.91 ± 1.57 μg/mL). The tested cyclohexane and dichloromethane extracts possessed moderate antibacterial and significant cytotoxic activity against both malignant (HeLa and N87) and healthy (MRC5) cell lines. Methanol extracts exhibited promising anti-Helicobacter activity without cytotoxicity against N87 and MRC5 cell lines.

对本文的引用
  1. Nowacka-Jechalke Natalia, Olech Marta, Nowak Renata, Mushroom Polyphenols as Chemopreventive Agents, in Polyphenols: Prevention and Treatment of Human Disease, 2018. Crossref

  2. Younis Ahmed M., Yosri Mohamed, Stewart Jennifer K., In vitro evaluation of pleiotropic properties of wild mushroom Laetiporus sulphureus, Annals of Agricultural Sciences, 64, 1, 2019. Crossref

  3. Gavryushina I. A., Gromovykh T. I., Feldman N. B., Lutsenko S. V., Ponomarenko V. I., Kisil O. V., Sadykova V. S., Antimicrobial Properties of Water-Soluble Polysaccharides and Alcoholic Extracts of <i>Laetiporus Sulphureus</i> (Bull.) Murrill Mycelium and Development of Biotechnology for Its Production in Immobilized Culture on Bacterial Cellulose, Antibiotics and Chemotherapy, 65, 1-2, 2020. Crossref

  4. Das Arpita, Chen Chiao-Ming, Mu Shu-Chi, Yang Shu-Hui, Ju Yu-Ming, Li Sing-Chung, Medicinal Components in Edible Mushrooms on Diabetes Mellitus Treatment, Pharmaceutics, 14, 2, 2022. Crossref

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