图书馆订阅: Guest
Begell Digital Portal Begell 数字图书馆 电子图书 期刊 参考文献及会议录 研究收集
国际药用蘑菇期刊
影响因子: 1.423 5年影响因子: 1.525 SJR: 0.431 SNIP: 0.661 CiteScore™: 1.38

ISSN 打印: 1521-9437
ISSN 在线: 1940-4344

国际药用蘑菇期刊

DOI: 10.1615/IntJMedMushr.v8.i2.40
pages 129-134

Effects of Polysaccharides Isolated from Agaricus brasiliensis (Agaricomycetideae) on Splenic Hematopoiesis in Mice

Yoshiaki Fujimiya
Division of Biotechnology, Sumitomo Forestry Tsukuba Research Institute, 3-2, Midorigahara, Tsukuba; and Department of Microbiology and Immunology, Hachinohe University School of Human Health Sciences, Hachinohe, Aomori 031-8566, Japan
Debra S. Groveman
Veterans Administration Hospital, White River Junction, VT 05009
Yoshihiro Takei
INA Research, K.K. Ina, Nagano 399-4501, Japan
Youichi Suzuki
Suzuki Neurosurgery Medical Center, Watari, Miyagi, 989-2301, Japan
Masahide Noji
Department of Clinical Nutrition, Suzuka University of Medical Science, Kishioka-cho, Suzuka, Japan

ABSTRACT

The administration of ethanol-soluble, boiling water-soluble, and ammonium oxalate-insoluble fractions (essentially β-1, 6-D glucose) isolated from the fruiting bodies of Agaricus brasiliensis into C3H/HeN mice resulted in a marked proliferation of cells of multicell lineages in the splenic compartment. Phenotypically increased expression of NK1.1+ on lymphoid cells and histologically increased proliferations of megakaryocytic progenitor cells were seen in the splenic compartment. These results indicate that β-1, 6-D polysaccharides may play a critical role in the maintenance of hematopoietic cells for compromised patients at the risk of infection associated with malignancy.


Articles with similar content:

The Anti-Inflammatory Effects of Lion's Mane Culinary-Medicinal Mushroom, Hericium erinaceus (Higher Basidiomycetes) in a Coculture System of 3T3-L1 Adipocytes and RAW264 Macrophages
International Journal of Medicinal Mushrooms, Vol.17, 2015, issue 7
Noriyasu Hirasawa, Kenji Ouchi, Koichiro Mori
IL-7 and IL-15: Biology and Roles in T-Cell Immunity in Health and Disease
Critical Reviews™ in Immunology, Vol.28, 2008, issue 4
Kyung-A Hwang, Insoo Kang, Sung-Hwan Park, Hang-Rae Kim
Royal Sun Medicinal Mushroom, Agaricus brasiliensis (Agaricomycetidae), Derived Polysaccharides Exert Immunomodulatory Activities In Vitro and In Vivo
International Journal of Medicinal Mushrooms, Vol.18, 2016, issue 2
Weilu Wei, Lijuan Wang, Yingrui Li, Huan Zhang, Leilei Fang, Yanqing Zhang, Junbo Xie
Inhibitory Effects of Extracts from Agaricus brasiliensis S. Wasser et al. (Agaricomycetideae) on Immediate Type Allergy Induced Compound 48/80 in ICR Mice
International Journal of Medicinal Mushrooms, Vol.7, 2005, issue 3
Sachiko Kawakami, Yasushi Chida, Masashi Mizuno
Role of the IL-12/IL-23 System in the Regulation of T-Cell Responses in Central Nervous System Inflammatory Demyelination
Critical Reviews™ in Immunology, Vol.24, 2004, issue 2
Bruno Gran, Guang-Xian Zhang, Abdolmohamad Rostami