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国际药用蘑菇期刊
影响因子: 1.423 5年影响因子: 1.525 SJR: 0.433 SNIP: 0.661 CiteScore™: 1.38

ISSN 打印: 1521-9437
ISSN 在线: 1940-4344

国际药用蘑菇期刊

DOI: 10.1615/IntJMedMushr.v12.i3.110
pages 317-325

History of the Study of Thrombolytic and Fibrinolytic Enzymes of Higher Basidiomycetes Mushrooms at the V.L. Komarov Botanical Institute in Saint Petersburg, Russia

Nina P. Denisova
V. L. Komarov Botanical Institute Russian Academy of Sciences Prof. Popova Str. 2 St. Petersburg 197376, Russia

ABSTRACT

The thrombolytic, fibrinolytic, milk-clotting, and general proteolytic activities of fruiting bodies of 400 species of Basidiomycetes belonging to various taxonomical and ecological groups were studied. A sufficient distinction between saprotrophic and symbiotrophic groups of Basidiomycetes in proteinase biosynthesis was established. It was found that the most pronounced proteolytic activity in combination with wide-range substrate specificity was characteristic for a group of saprotrophic mushrooms, whereas the symbiotrophic fungi were characterized by a low level or even complete absence of the aforementioned types of activity. The most pronounced fibrinolytic and thrombolytic activities were noted for lignotrophic saprotrophs and litter saprotrophs associated with lignin-cellulose complexes (rotten wood, compost, substrata, etc.). The list of species of Basidiomycetes that synthesize enzymes possessing high thrombolytic activity and low general proteolytic activity is presented.


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