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ISSN 打印: 1521-9437

ISSN 在线: 1940-4344

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Purification of Caffeic Acid as an Antioxidant from Submerged Culture Mycelia of Phellinus linteus (Berk. et Curt.) Teng (Aphyllophoromycetideae)

卷 5, 册 2, 2003, 6 pages
DOI: 10.1615/InterJMedicMush.v5.i2.50
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摘要

Phellinus linteus mycelia have many pharmacological effects although their pharmacological efficacy principles have not been known before. In the course of screening for biological activity of the extracts of Ph. Linteus mycelia, we found strong antioxidative activity in the extract. Therefore, we tried to isolate the active principle(s) from the extract. The isolation of the active compound was guided by superoxide anion radical scavenging activity. As a result, caffeic acid was isolated as an active compound. The IC50 of the compound was 3.05 μg/mL (16.9 μM).

对本文的引用
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  2. Ruimi Nili, Petrova Roumyana D., Agbaria Riad, Sussan Sherbel, Wasser Solomon P., Reznick Abraham Z., Mahajna Jamal, Inhibition of TNFα-induced iNOS expression in HSV-tk transduced 9L glioblastoma cell lines by Marasmius oreades substances through NF-κB- and MAPK-dependent mechanisms, Molecular Biology Reports, 37, 8, 2010. Crossref

  3. Petrova Roumyana D., Mahajna Jamal, Reznick Abraham Z., Wasser Solomon P., Denchev Cvetomir M., Nevo Eviatar, Fungal substances as modulators of NF-κB activation pathway, Molecular Biology Reports, 34, 3, 2007. Crossref

  4. De Silva Dilani D., Rapior Sylvie, Fons Françoise, Bahkali Ali H., Hyde Kevin D., Medicinal mushrooms in supportive cancer therapies: an approach to anti-cancer effects and putative mechanisms of action, Fungal Diversity, 55, 1, 2012. Crossref

  5. Evidente Antonio, Kornienko Alexander, Cimmino Alessio, Andolfi Anna, Lefranc Florence, Mathieu Véronique, Kiss Robert, Fungal metabolites with anticancer activity, Nat. Prod. Rep., 31, 5, 2014. Crossref

  6. Park Hye-Jin, Current Uses of Mushrooms in Cancer Treatment and Their Anticancer Mechanisms, International Journal of Molecular Sciences, 23, 18, 2022. Crossref

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