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ISSN 打印: 1521-9437

ISSN 在线: 1940-4344

The Impact Factor measures the average number of citations received in a particular year by papers published in the journal during the two preceding years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) IF: 1.2 To calculate the five year Impact Factor, citations are counted in 2017 to the previous five years and divided by the source items published in the previous five years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) 5-Year IF: 1.4 The Immediacy Index is the average number of times an article is cited in the year it is published. The journal Immediacy Index indicates how quickly articles in a journal are cited. Immediacy Index: 0.3 The Eigenfactor score, developed by Jevin West and Carl Bergstrom at the University of Washington, is a rating of the total importance of a scientific journal. Journals are rated according to the number of incoming citations, with citations from highly ranked journals weighted to make a larger contribution to the eigenfactor than those from poorly ranked journals. Eigenfactor: 0.00066 The Journal Citation Indicator (JCI) is a single measurement of the field-normalized citation impact of journals in the Web of Science Core Collection across disciplines. The key words here are that the metric is normalized and cross-disciplinary. JCI: 0.34 SJR: 0.274 SNIP: 0.41 CiteScore™:: 2.8 H-Index: 37

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Liperoxidation and Cyclooxygenase Enzyme Inhibitory Compounds from the Lipophilic Extracts of Some Culinary-Medicinal Higher Basidiomycetes Mushrooms

卷 11, 册 4, 2009, pp. 375-382
DOI: 10.1615/IntJMedMushr.v11.i4.40
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摘要

We have determined the bioactive constituents in the higher Basidiomycetes edible mushrooms Pholiota nameko, Lentinus edodes, and Pleurotus ostreatus using in vitro lipid peroxidation (LPO) and cyclooxygenase enzyme (COX) inhibitory assays. Ethyl acetate extract of nameko was the most active against LPO, with an inhibition value of 81% at 250 μg/mL. Shiitake and oyster mushroom extracts inhibited LPO by 39% and 52%, respectively, at 250 μg/mL. In the COX assay, the ethyl acetate extracts of nameko, shiitake, and oyster mushrooms inhibited COX-1 and -2 enzymes by 39%, 34%, and 54% and 87%, 92%, and 75%, respectively, at 250 μg/mL. A bioassay-guided purification yielded linoleic acid (1), ergosterol (2), ergosterol peroxide (3), and a glycosphingolipid (4) along with a glyceride fraction (GF), as confirmed by spectroscopic methods. All three mushrooms have shown the presence of compounds 1 and 3 as common constituents. Compound 2 was isolated from both nameko and shiitake mushrooms. Compound 4 was isolated from shiitake and oyster mushrooms. The GF obtained from oyster mushrooms inhibited LPO by 92% and COX-1 and -2 enzymes by 43% and 92%, respectively, at 25 μg/mL.

对本文的引用
  1. Schneider Inga, Kressel Gaby, Meyer Annette, Krings Ulrich, Berger Ralf G, Hahn Andreas, Lipid lowering effects of oyster mushroom (Pleurotus ostreatus) in humans, Journal of Functional Foods, 3, 1, 2011. Crossref

  2. Dissanayake Amila A., Zhang Chuan-Rui, Mills Gary L., Nair Muraleedharan G., Cultivated maitake mushroom demonstrated functional food quality as determined by in vitro bioassays, Journal of Functional Foods, 44, 2018. Crossref

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