每年出版 12 期
ISSN 打印: 1521-9437
ISSN 在线: 1940-4344
Indexed in
Ganoderma lucidum (Curt.: Fr.) P. Karst. (Aphyllophoromycetideae)−A Mushrooming Medicinal Mushroom
摘要
The medicinal properties of Ganoderma lucidum (Curt.: Fr.) P. Karst. have been recognized for many centuries in China and other parts of Asia. During the last two decades, there has been a sharp increase in the level of commercial interest in G. lucidum products, not only in Asian countries but also in North America and Europe. Latest available estimates put the annual value of G. lucidum products worldwide at more than US $1.6 billion. This increased demand has stimulated improvements in artificial cultivation methods, of which currently the most widely adopted are the wood log, short wood segment, tree stump, sawdust bag, and bottle procedures. The application of modern analytical techniques has revealed the mushroom to contain numerous bioactive compounds including polysaccharides, triterpenes, and immunomodulatory proteins. Many of these compounds have anticancer and antitumor properties that appear to be based on an enhancement of the host immune system rather than on a direct cytocidal effect. Further expansion of the market for G. lucidum products will require the introduction of more reproducible protocols for mushroom production and downstream processing to improve quality control and ensure enduring public trust.
-
Jin Xingzhong, Ruiz Beguerie Julieta, Sze Daniel Man-yeun, Chan Godfrey CF, Jin Xingzhong, Ganoderma Lucidum (Reishi mushroom) for cancer treatment, in Cochrane Database of Systematic Reviews, 2009. Crossref
-
Wachtel-Galor Sissi, Tomlinson Brian, Benzie Iris F. F., Ganoderma lucidum(‘Lingzhi’), a Chinese medicinal mushroom: biomarker responses in a controlled human supplementation study, British Journal of Nutrition, 91, 2, 2004. Crossref
-
Lin Jing-Wei, Hao Li-Xia, Xu Gui-Xue, Sun Fei, Gao Feng, Zhang Ren, Liu Li-Xia, Molecular cloning and recombinant expression of a gene encoding a fungal immunomodulatory protein from Ganoderma lucidum in Pichia pastoris, World Journal of Microbiology and Biotechnology, 25, 3, 2009. Crossref
-
Yue Grace G.L., Fung Kwok-Pui, Tse Gary M.K., Leung Ping-Chung, Lau Clara B.S., Comparative Studies of Various Ganoderma Species and Their Different Parts with Regard to Their Antitumor and Immunomodulating Activities In Vitro, The Journal of Alternative and Complementary Medicine, 12, 8, 2006. Crossref
-
Yue Grace G. L., Fung Kwok-Pui, Leung Ping-Chung, Lau Clara B. S., Comparative studies on the immunomodulatory and antitumor activities of the different parts of fruiting body ofGanoderma lucidumandGanodermaspores, Phytotherapy Research, 22, 10, 2008. Crossref
-
Moradali Mohammad-Fata, Mostafavi Hossein, Ghods Shirin, Hedjaroude Ghorban-Ali, Immunomodulating and anticancer agents in the realm of macromycetes fungi (macrofungi), International Immunopharmacology, 7, 6, 2007. Crossref
-
Li Bin, Lee Dong-Sung, Kang Yue, Yao Nai-Qi, An Ren-Bo, Kim Youn-Chul, Protective effect of ganodermanondiol isolated from the Lingzhi mushroom against tert-butyl hydroperoxide-induced hepatotoxicity through Nrf2-mediated antioxidant enzymes, Food and Chemical Toxicology, 53, 2013. Crossref
-
Thyagarajan Anita, Jedinak Andrej, Nguyen Hai, Terry Colin, Baldridge Lee Ann, Jiang Jiahua, Sliva Daniel, Triterpenes FromGanoderma LucidumInduce Autophagy in Colon Cancer Through the Inhibition of p38 Mitogen-Activated Kinase (p38 MAPK), Nutrition and Cancer, 62, 5, 2010. Crossref
-
Dominique Claude MOSSEBO, Rose T AMBIT, Marie Claire MACHOUART, Germain KANSCI, A new ethanol-based macrochemical test combined with a cultural character in the process of identification of the cosmopolitan wood-decayer, Ganoderma resinaceum Boud. (Basidiomycota), Journal of Yeast and Fungal Research, 6, 1, 2015. Crossref
-
Jin Xingzhong, Ruiz Beguerie Julieta, Sze Daniel Man-yeun, Chan Godfrey CF, Jin Xingzhong, Ganoderma lucidum(Reishi mushroom) for cancer treatment, in Cochrane Database of Systematic Reviews, 2012. Crossref
-
Leskosek-Cukalovic I., Despotovic S., Lakic N., Niksic M., Nedovic V., Tesevic V., Ganoderma lucidum — Medical mushroom as a raw material for beer with enhanced functional properties, Food Research International, 43, 9, 2010. Crossref
-
Gao Yihuai, Chan Eli, Zhou Shufeng, Immunomodulating Activities ofGanoderma, a Mushroom with Medicinal Properties, Food Reviews International, 20, 2, 2004. Crossref
-
Further Reading, in Compendia of World's Medicinal Flora, 2006. Crossref
-
Ji Zhe, Tang Qingjiu, Zhang Jinsong, Yang Yan, Jia Wei, Pan Yingjie, Immunomodulation of RAW264.7 macrophages by GLIS, a proteopolysaccharide from Ganoderma lucidum, Journal of Ethnopharmacology, 112, 3, 2007. Crossref
-
Turło J., Gutkowska B., Herold F., Krzyczkowski W., Błażewicz A., Kocjan R., Optimizing vitamin B12 biosynthesis by mycelial cultures of Lentinula edodes (Berk.) Pegl., Enzyme and Microbial Technology, 43, 4-5, 2008. Crossref
-
Ofodile L. N., Uma N., Grayer R. J., Ogundipe O. T., Simmonds M. S. J., Antibacterial Compounds from the Mushroom Ganoderma colossum from Nigeria, Phytotherapy Research, 26, 5, 2012. Crossref
-
Zhou Xuan-Wei, Su Kai-Qi, Zhang Yong-Ming, Applied modern biotechnology for cultivation of Ganoderma and development of their products, Applied Microbiology and Biotechnology, 93, 3, 2012. Crossref
-
Rao Juluri R., Stuart Elborn J., Cherie Millar B., Moore John E., Potential increased risk of hypersensitivity pneumonitis (HP) in complementary medicine practitioners associated with handling exotic mushroom varieties, Complementary Therapies in Clinical Practice, 11, 2, 2005. Crossref
-
Choong Yew Keong, Sun Su-Qin, Zhou Qun, Ismail Zakiah, Rashid Badrul Amini Abdul, Tao Jia-Xun, Determination of storage stability of the crude extracts of Ganoderma lucidum using FTIR and 2D-IR spectroscopy, Vibrational Spectroscopy, 2011. Crossref
-
Chung Wai Y., Yow Christine M.N., Benzie Iris F.F., Assessment of membrane protection by traditional Chinese medicines using a flow cytometric technique: preliminary findings, Redox Report, 8, 1, 2003. Crossref
-
Zjawiony Jordan, Antimicrobial and Antiviral Metabolites from Polypore Fungi, in Novel Therapeutic Agents from Plants, 2009. Crossref
-
Martins Anabela, The Numbers Behind Mushroom Biodiversity, in Wild Plants, Mushrooms and Nuts, 2016. Crossref
-
Pheba L George, Venkateswara R Sripathi, Seloame T Nyaku, Govind C Sharma, Ramesh V Kantety, DNA-based identification of Lentinula edodes strains with species-specific primers, African Journal of Biotechnology, 15, 7, 2016. Crossref
-
Wachtel-Galor Sissi, Choi Siu-Wai, Benzie Iris F.F., Effect ofGanoderma lucidumon human DNA is dose dependent and mediated by hydrogen peroxide, Redox Report, 10, 3, 2005. Crossref
-
Wachtel-galor Sissi, Szeto Yim-tong, Tomlinson Brian, Benzie Iris Ff, Ganoderma lucidum(‘Lingzhi’); acute and short-term biomarker response to supplementation, International Journal of Food Sciences and Nutrition, 55, 1, 2004. Crossref
-
Huo Guangming, Zhang Liyang, Chen Chien-Yi, Determination and Importance of Trace Elements in Chinese Medicinal Herbs Used for Healthcare and Medical Treatments, in Development and Uses of Biofortified Agricultural Products, 2008. Crossref
-
Chan Kar-Man, Yue Grace Gar-Lee, Li Ping, Wong Eric Chun-Wai, Lee Julia Kin-Ming, Kennelly Edward J., Lau Clara Bik-San, Screening and analysis of potential anti-tumor components from the stipe of Ganoderma sinense using high-performance liquid chromatography/time-of-flight mass spectrometry with multivariate statistical tool, Journal of Chromatography A, 1487, 2017. Crossref
-
Jargalmaa Suldbold, Eimes John A., Park Myung Soo, Park Jae Young, Oh Seung-Yoon, Lim Young Woon, Taxonomic evaluation of selected Ganoderma species and database sequence validation, PeerJ, 5, 2017. Crossref
-
Zhou Xuan-Wei, Cultivation ofGanoderma lucidum, in Edible and Medicinal Mushrooms, 2017. Crossref
-
Shi Yu-ling, James Anthony E., Benzie Iris F.F., Buswell John A., Mushroom-derived preparations in the prevention of H2O2-induced oxidative damage to cellular DNA, Teratogenesis, Carcinogenesis, and Mutagenesis, 22, 2, 2002. Crossref
-
Sudheer Surya, Alzorqi Ibrahim, Manickam Sivakumar, Ali Asgar, Bioactive Compounds of the Wonder Medicinal Mushroom “Ganoderma lucidum”, in Sweeteners, 2018. Crossref
-
Meletis Chris D., Barker Jason E., Medicinal Mushrooms:A Selective Overview, Alternative and Complementary Therapies, 11, 3, 2005. Crossref
-
Qu Zheng-Wei, Zhou Si-Ya, Guan Shi-Xin, Gao Rui, Duan Zuo-Wen, Zhang Xin, Sun Wei-Yan, Fan Wen-Li, Chen Shui-Sen, Chen Li-Jing, Lin Jing-Wei, Ruan Yan-Ye, Recombinant Expression and Bioactivity Comparison of Four Typical Fungal Immunomodulatory Proteins from Three Main Ganoderma Species, BMC Biotechnology, 18, 1, 2018. Crossref
-
Ahmed Hammad, Aslam Muhammad, Evaluation of aphrodisiac activity of ethanol extract of Ganoderma lucidum in male Wistar rats, Clinical Phytoscience, 4, 1, 2018. Crossref
-
JI ZHE, TANG QINGJIU, HAO RUIXIA, ZHANG JINSONG, PAN YINGJIE, Induction of apoptosis in the SW620 colon carcinoma cell line by triterpene-enriched extracts from Ganoderma lucidum through activation of caspase-3, Oncology Letters, 2, 3, 2011. Crossref
-
Yuen John, Buswell John, Benzie Iris, Ganoderma lucidum (Lingzhi or Reishi), in Herbal Medicine, 20115386, 2011. Crossref
-
Du Zhuo, Dong Cai-Hong, Wang Ke, Yao Yi-Jian, Classification, Biological Characteristics and Cultivations of Ganoderma, in Ganoderma and Health, 1181, 2019. Crossref
-
Wong Jack Ho, Ng Tzi Bun, Wang Hexiang, Cheung Randy Chi Fai, Ng Charlene Cheuk Wing, Ye Xiuyun, Yang Jie, Liu Fang, Ling Chen, Chan Ki, Ye Xiujuan, Chan Wai Yee, Antifungal Proteins with Antiproliferative Activity on Cancer Cells and HIV-1 Enzyme Inhibitory Activity from Medicinal Plants and Medicinal Fungi, Current Protein & Peptide Science, 20, 3, 2019. Crossref
-
Sudheer Surya, Alzorqi Ibrahim, Manickam Sivakumar, Ali Asgar, Bioactive Compounds of the Wonder Medicinal Mushroom “Ganoderma lucidum”, in Bioactive Molecules in Food, 2019. Crossref
-
Ahmad Md Faruque, Ganoderma lucidum: A Macro Fungus with Phytochemicals and Their Pharmacological Properties, in Plant and Human Health, Volume 2, 2019. Crossref
-
Yuen John W. M., Gohel Mayur Danny I., Anticancer Effects of Ganoderma lucidum: A Review of Scientific Evidence, Nutrition and Cancer, 53, 1, 2005. Crossref
-
Liu Rui, Zhu Ting, Yang Tao, Yang Zhengyan, Ren Ang, Shi Liang, Zhu Jing, Yu Hanshou, Zhao Mingwen, Nitric oxide regulates ganoderic acid biosynthesis by the S‐nitrosylation of aconitase under heat stress in Ganoderma lucidum , Environmental Microbiology, 23, 2, 2021. Crossref
-
Gracián-Alcaide Carlos, Maldonado-Lobón Jose A., Ortiz-Tikkakoski Elisabeth, Gómez-Vilchez Alejandro, Fonollá Juristo, López-Larramendi Jose L., Olivares Mónica, Blanco-Rojo Ruth, Effects of a Combination of Elderberry and Reishi Extracts on the Duration and Severity of Respiratory Tract Infections in Elderly Subjects: A Randomized Controlled Trial, Applied Sciences, 10, 22, 2020. Crossref
-
Mawar Ritu, Ram Ladhu, Deepesh , Mathur Tanu, Ganoderma, in Beneficial Microbes in Agro-Ecology, 2020. Crossref
-
Agustin Fauzia, Elihasridas , Juliyarsi Indri, The effect of urea supplementation and incubation time in fermentation process of bagasse by using Ganoderma lucidum on the growth of G. lucidum and the nutritive value of bagasse, IOP Conference Series: Earth and Environmental Science, 287, 1, 2019. Crossref
-
Jin Xingzhong, Ruiz Beguerie Julieta, Sze Daniel Man-yuen, Chan Godfrey CF, Ganoderma lucidum (Reishi mushroom) for cancer treatment, Cochrane Database of Systematic Reviews, 2019, 1, 2016. Crossref
-
Do Dat Tran, Lam Dang Hoang, Nguyen Tai, Phuong Mai Tran Thi, Phan Le Thao My, Vuong Hoai Thanh, Nguyen Duc Viet, Linh Ngo Thi Thuy, Hoang Minh Nam, Mai Thanh Phong, Nguyen Huu Hieu, Sarkar Nirmal Kumar, Utilization of Response Surface Methodology in Optimization of Polysaccharides Extraction from Vietnamese Red Ganoderma lucidum by Ultrasound-Assisted Enzymatic Method and Examination of Bioactivities of the Extract, The Scientific World Journal, 2021, 2021. Crossref
-
Gryzenhout Marieka, Ghosh Soumya, Tchotet Tchoumi James Michel, Vermeulen Marcele, Kinge Tonjock Rosemary, Ganoderma: Diversity, Ecological Significances, and Potential Applications in Industry and Allied Sectors, in Industrially Important Fungi for Sustainable Development, 2021. Crossref
-
Shanmugavelu Mathipriya, Sevugaperumal Ganesan, Screening and Potential Uses of Contaminated Spent Mushroom (Pleurotus spp.), in Emerging Contaminants, 2021. Crossref
-
Chang Shuting, Buswell John, , 2022. Crossref
-
Ahmad Rizwan, Riaz Muhammad, Khan Aslam, Aljamea Ahmed, Algheryafi Mohammad, Sewaket Deya, Alqathama Aljawharah, Ganoderma lucidum (Reishi) an edible mushroom; a comprehensive and critical review of its nutritional, cosmeceutical, mycochemical, pharmacological, clinical, and toxicological properties , Phytotherapy Research, 35, 11, 2021. Crossref
-
Jandaik Savita, Gupta Satish Kumar, Cultivation Technology of the Fungus Ganoderma lucidum (Curtis) P. Karst, in Biology, Cultivation and Applications of Mushrooms, 2022. Crossref
-
Postemsky Pablo, Bidegain Maximiliano, González Matute Ramiro, Figlas Débora, Caprile Daniela, Salazar-Vidal Viviana, Saparrat Mario, , 2022. Crossref
-
Raman Jegadeesh, Lakshmanan Hariprasath, Hyun-Jae Shin, Jang Kab-yel, The Nutritional and Pharmacological Potential of Medicinal Mushroom “Ganoderma lucidum (Lingzhi or Reishi)”, in Biology, Cultivation and Applications of Mushrooms, 2022. Crossref
-
Tiwari Mishra Shraddha, Kaladhar Dowluru SVGK, MEDICINAL PROPERTIES AND ECONOMIC IMPORTANCE OF AgNP FROM Ganoderma Lucidum: A REVIEW, GLOBAL JOURNAL FOR RESEARCH ANALYSIS, 2022. Crossref
-
Klupp Nerida L, Chang Dennis, Hawke Fiona, Kiat Hosen, Cao Huijuan, Grant Suzanne J, Bensoussan Alan, Ganoderma lucidum mushroom for the treatment of cardiovascular risk factors, Cochrane Database of Systematic Reviews, 2021, 9, 2015. Crossref