图书馆订阅: Guest
Begell Digital Portal Begell 数字图书馆 电子图书 期刊 参考文献及会议录 研究收集
国际药用蘑菇期刊
影响因子: 1.423 5年影响因子: 1.525 SJR: 0.431 SNIP: 0.661 CiteScore™: 1.38

ISSN 打印: 1521-9437
ISSN 在线: 1940-4344

国际药用蘑菇期刊

DOI: 10.1615/IntJMedMushr.v13.i6.70
pages 553-558

In vitro Antibacterial Activities of Aqueous Extracts from Algerian Desert Truffles (Terfezia and Tirmania, Ascomycetes) Against Pseudomonas aeruginosa and Staphylococcus aureus

Hicham Gouzi
Laboratory of Organic Chemistry, Natural Products, and Analysis (COSNA), Department of Chemistry, Faculty of Science, Abou Bekr Belkaid University, Tlemcen, Algeria
Larbi Belyagoubi
Department of Biology, Faculty of Science, Amar Telidji University, Laboratory of Microbiology, Laghouat 03000, Algeria
Khadidja Nesrine Abdelali
Department of Biology, Faculty of Science, Amar Telidji University, Laboratory of Microbiology, Laghouat 03000, Algeria
Adila Khelifi
Department of Biology, Faculty of Science, Amar Telidji University, Laboratory of Microbiology, Laghouat 03000, Algeria

ABSTRACT

The aim of this study is to evaluate the in vitro effects of aqueous extracts of three species of Algerian desert truffles (Terfezia claveryi, T. leonis, and Tirmania nivea) on the growth of Pseudomonas aeruginosa and Staphylococcus aureus. The antimicrobial activity of the three aqueous extracts was tested using the agar well diffusion and kinetic bacterial growth curves methods. The aqueous extracts of Terfezia claveryi and Tirmania nivea were found to possess a very powerful antibacterial activity against both S. aureus and P. aeruginosa using agar well diffusion. Using 4% and 11% of the aqueous extracts of T. claveryi and T. nivea in the growth medium of S. aureus caused a significant inhibition of S. aureus growth by 86.48% and 99.09%, respectively. The aqueous extracts of T. claveryi and T. nivea were found to cause a significant inhibition of the growth of P. aeruginosa by 71.11% and 100%, respectively. However, the aqueous extract of Terfecia leonis did not show any antibacterial activity. Therefore, T. claveryi and Tirmania nivea can be considered a source of natural therapeutic agents that can be used to treat eye infections caused by resistant bacteria such as P. aeruginosa and S. aureus.