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国际流体力学研究期刊
ESCI SJR: 0.206 SNIP: 0.446 CiteScore™: 0.9

ISSN 打印: 2152-5102
ISSN 在线: 2152-5110

国际流体力学研究期刊

DOI: 10.1615/InterJFluidMechRes.v42.i2.50
pages 149-169

Computational Analysis of Transient non-Newtonian Blood Flow in Magnetic Targeting Drug Delivery in Stenosed Carotid Bifurcation Artery

Haleh Alimohamadi
PhD student
Mohsen Imani
School of Electrical and Computer Engineering, University of Tehran Tehran, Iran
Behjat Forouzandeh
School of Electrical and Computer Engineering, University of Tehran Tehran, Iran

ABSTRACT

This paper presents pulsatile blood flow simulation in a carotid bifurcation under the action of external magnetic field. Previous investigations neglected the effect of transient magnetic field on non-Newtonian blood flow through a coupled free and porous media. In this study for closing to a real phenomenon, arterial walls and two fatty deposited atherosclerotic plaques are considered as different porous media, blood is assumed as a generalized non-Newtonian biomagnetic fluid (with Power law and Carreau models) and time dependent inlet velocity varies by the frequency of human heart beating cycle. Because of magnetic field existence, two big vortexes are created at the plaques' edges and the temperature, shear stress, vertical velocity and pressure distribution along the stenosis region have been affected noticeably. The results show by applying MnF = 107 and MnM = 102 magnetic field intensity the values of temperature, absolute maximum pressure and shear stress go up 7.35 %, 5.55 times and 5.33 times (62.16 %,4.08 times and 6 times) respect with normal condition on the upper (lower) plaques respectively. Examining the role of porosity factor indicates that by progressing stenosis disease and hardening atherosclerotic plaques, magnetotherapy treatment lose its efficiency due to sever reduction in available maximum blood temperature, fluid flux and average Nusselt number.


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