RT Journal Article
ID 277965fb73c4dbb2
A1 Kakouri, Eleni 
A1 Hatziagapiou, Kyriaki 
A1 Bethanis, Kostas 
A1 Nikola, Olti Alexandra 
A1 Lambrou, George I.
A1 Tarantilis, Petros A. 
T1 Tumor-Suppressing Properties of <i>Crocus sativus L.</i>: Nature as an Anti-Cancer Agent
JF Critical Reviews&trade; in Oncogenesis
JO CRO
YR 2017
FD 2018-02-26
VO 22
IS 3-4
SP 263
OP 273
K1 <i>Crocus sativus</i>
K1 cancer
K1 saffron
K1 antioxidant
K1 anti-cancer agent
AB Cancer is a growing problem because it is a chronic disease that affects, not only patient health, but also its daily living. Concurrent cancer therapies have ameliorated cancer prevalence, but the severity and frequency of toxicity and side effects during therapy have led the scientific community to rediscover the possible therapeutic effectiveness of herbs and spices. <i>Crocus sativus L.</i>, commonly known as saffron, has been used in folk medicine for centuries. Today, data from numerous <i>in vivo</i> and <i>in vitro</i> studies support its anti-cancer activity,
making it a promising anti-cancer agent for study. In the present review, we focus on the anti-cancer activity of <i>C. sativus</i> and its derivates. Medications that are currently used as chemotherapeutic or anti-cancer agents are associated with side effects whether used at effective doses or at levels that exceed the therapeutic dose. Therefore, many cancer survivors suffer from serious and even life-threatening long- or short-term sequelae, so the development of alternative/coadjutant drugs is imperative.

PB Begell House
LK https://www.dl.begellhouse.com/journals/439f422d0783386a,68adc3ff72d697d8,277965fb73c4dbb2.html