RT Journal Article ID 32590f0022a7ffa8 A1 Hosseini, Zahra A1 Iranpanah, Behzad T1 Advances in Frame-based versus Frameless Stereotaxic Methods in Localization of Coordinates During Neurosurgery JF Visualization, Image Processing and Computation in Biomedicine JO VIPCB YR 2013 FD 2013-07-09 VO 2 IS 1 OP 0 K1 stereotaxy K1 frameless K1 frame-based K1 localization K1 accuracy K1 registration K1 intra-operative K1 medical imaging K1 multimodality AB The idea proposed by Horsley and Clark, to address the accuracy requirements of surgical procedures performed on the brain, was the foundation of stereotaxic techniques. These pioneers utilized a frame-based configuration, to create an extracranial reference system and identified the anterior and posterior commissure (AC-PC) on x-ray images to localize targets of interest. Proliferation of computed tomography has given rise to the improvement of frame-based stereotaxy and advent of frameless techniques. Numerous studies have been performed to validate, apply, and further improve these techniques. Application of frameless techniques have been found to be more robust when compared to frame-based systems. Furthermore, surgical procedures performed through frameless methods have been associated with shorter surgeries and hospital stays. Nevertheless, both techniques have limitations, such as an inability to compensate for brain shift, which results in localization mismatch. Intraoperative imaging has been employed by a number of groups to create a repeatable procedure by taking into account dynamic changes of intracranial structures. PB Begell House LK https://www.dl.begellhouse.com/journals/7e4ff0643eace965,0f56de4765dd934d,32590f0022a7ffa8.html