RT Journal Article ID 3624fb0158cb6809 A1 Chen, Gong A1 Chan, Chow Khuen A1 Guo, Zhao A1 Yu, Haoyong T1 A Review of Lower Extremity Assistive Robotic Exoskeletons in Rehabilitation Therapy JF Critical Reviews™ in Biomedical Engineering JO CRB YR 2013 FD 2014-04-14 VO 41 IS 4-5 SP 343 OP 363 K1 Neurorehabilitation K1 robotics K1 exoskeleton K1 control strategies K1 rehabilitation therapy K1 robotic rehabilitation K1 mechanical design K1 actuation system AB The rapid advancement of robotics technology in recent years has pushed the development of a distinctive field of robotic applications, namely robotic exoskeletons. Because of the aging population, more people are suffering from neurological disorders such as stroke, central nervous system disorder, and spinal cord injury. As manual therapy seems to be physically demanding for both the patient and therapist, robotic exoskeletons have been developed to increase the efficiency of rehabilitation therapy. Robotic exoskeletons are capable of providing more intensive patient training, better quantitative feedback, and improved functional outcomes for patients compared to manual therapy. This review emphasizes treadmill-based and over-ground exoskeletons for rehabilitation. Analyses of their mechanical designs, actuation systems, and integrated control strategies are given priority because the interactions between these components are crucial for the optimal performance of the rehabilitation robot. The review also discusses the limitations of current exoskeletons and technical challenges faced in exoskeleton development. A general perspective of the future development of more effective robot exoskeletons, specifically real-time biological synergy-based exoskeletons, could help promote brain plasticity among neurologically impaired patients and allow them to regain normal walking ability. PB Begell House LK https://www.dl.begellhouse.com/journals/4b27cbfc562e21b8,4566441101015d3d,3624fb0158cb6809.html