%0 Journal Article %A Tsai, Jie-Chung %A Lung, Ming-Yeou %D 2009 %I Begell House %K Phellinus igniarius, medicinal mushrooms, intracellular polysaccharide, exopolysaccharide, antioxidant activity %N 4 %P 383-394 %R 10.1615/IntJMedMushr.v11.i4.50 %T Antioxidant Properties of Polysaccharides from the Willow Bracket Medicinal Mushroom, Phellinus igniarius (L.) Quél. (Aphyllophoromycetideae) in Submerged Culture %U https://www.dl.begellhouse.com/journals/708ae68d64b17c52,4554be083929b23c,51f0c47f5d139595.html %V 11 %X Investigated were antioxidant properties of intracellular polysaccharides (IPS) and exopolysaccharides (EPS) obtained respectively from mycelia and filtrates of submerged culture by Phellinus igniarius in a stirred-tank bioreactor. Also examined were superoxide and 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical-scavenging activities, chelating ability, reducing power, and antioxidant activity (AOA) by IPS and EPS. The high number average molecular weights of EPS (835 kDa) and IPS (574 kDa) were obtained, and their protein/polysaccharide ratios of IPS and EPS are equivalent (1.80%) by Ph. igniarius submerged culture. Low EC50 values below 5 mg/mL were relied upon as evidence that EPS possessed good antioxidant activity, scavenging effect on DPPH radicals, chelating effect on ferrous ions, and scavenging effect on superoxide anions, whereas IPS exhibited good reducing power, chelating effect on ferrous ions and scavenging effect on superoxide anions. The positive results of this research may lead to the development of a potential polysaccharide-related antioxidant for treating human disease. %8 2009-11-16