RT Journal Article ID 57b81ce9742fa347 A1 Motoi, Masuro A1 Motoi, Akitomo A1 Yamanaka, Daisuke A1 Ohno, Naohito T1 Open-Label Study of the Influence of Food Containing the Royal Sun Mushroom, Agaricus brasiliensis KA21 (Higher Basidiomycetes), on the Quality of Life of Healthy Human Volunteers JF International Journal of Medicinal Mushrooms JO IJM YR 2015 FD 2015-12-14 VO 17 IS 9 SP 799 OP 817 K1 medicinal mushrooms K1 Agaricus brasiliensis K1 Agaricus blazei K1 sleep quality K1 clinical study K1 enhancement of immunity K1 evaluation of safety AB We conducted an open-label study in which food containing Agaricus brasiliensis KA21 was consumed continuously for 12 weeks. A questionnaire for subjective evaluation of the efficacy of this food (hereafter, subjective evaluation questionnaire) revealed significant improvements compared with before its intake; there were improvements in the scores of the amounts of hair loss and gray hair, fatigue and general malaise, eye strain, shoulder stiffness, coldness of extremities, difficulty staying awake during the day, and ease of getting out of bed. These findings suggest that intake of food containing A. brasiliensis KA21 results in the above-mentioned subjectively evaluated improvements, and the possibility that A. brasiliensis KA21 improves the body's immunity. Moreover, no issues regarding the safety of the test food were found. PB Begell House LK https://www.dl.begellhouse.com/journals/708ae68d64b17c52,336a63ca4b6b8f52,57b81ce9742fa347.html