RT Journal Article ID 60ccf92e5c27d9e5 A1 Karpatkin, Herb I. A1 Cohen, Evan T. A1 DiCarrado, Stefanie A1 Dungan, Bridget A1 Potrzeba, Jake A1 Huallpa, Elizabeth A1 Parrott, J. Scott T1 The Effect of Intermittent vs. Continuous Training on Walking Endurance and Fatigue in People with Multiple Sclerosis: A Randomized, Crossover Trial JF Critical Reviews™ in Physical and Rehabilitation Medicine JO CRP YR 2016 FD 2016-12-13 VO 28 IS 1-2 SP 33 OP 45 K1 multiple sclerosis K1 walking K1 gait K1 fatigue K1 rehabilitation AB Objective: To compare effects of an intermittent and continuous walking program on walking endurance and fatigue in people with multiple sclerosis (MS)
Design: A randomized crossover prospective study
Setting: An outpatient rehabilitation clinic
Patients: A convenience sample of 12 participants with MS (median Expanded Disability Status Scale = 3.0, interquartile range [IQR] 3.25); 9 participants completed the study.
Interventions: The intervention consisted of eight 6-minute-long walks (2x/week for 4 weeks). The continuous condition consisted of 6 continuous minutes of walking. The intermittent condition consisted of three 2-minute bouts with 2-minute rests. After a 4-week detraining period, participants performed the second training condition.
Main Outcome Measurements: Outcomes included fatigue severity scale (FSS), the 6-minute walk test (6MWT), and the difference in a 100-mm visual analog scale of fatigue (ΔVAS-F) measured immediately before and after the 6MWT.
Results: The 6MWT distance increased after intermittent training (43.6 m, p = .013) and decreased after continuous training (−18.0 m, p = .362). The FSS decreased after intermittent training (p = .032) but not after continuous training. No differences were found in ΔVAS-F.
Conclusion: Intermittent training was superior to continuous training in improving walking and fatigue. Intermittent walking training should be considered to improve walking endurance and decrease fatigue in people with MS. PB Begell House LK https://www.dl.begellhouse.com/journals/757fcb0219d89390,7d05545f5ad8aa9c,60ccf92e5c27d9e5.html