RT Journal Article ID 6570b94e72937811 A1 Yue, Patrick Ying-Kit A1 Wong, Yi-Yi A1 Chan, Tony Yuk-Kit A1 Law, Carman Ka-Man A1 Tsoi, Yeuk-Ki A1 Leung, Kelvin Sze-Yin T1 Review of Biological and Pharmacological Activities of the Endemic Taiwanese Bitter Medicinal Mushroom, Antrodia camphorata (M. Zang et C. H. Su) Sh. H. Wu et al. (Higher Basidiomycetes) JF International Journal of Medicinal Mushrooms JO IJM YR 2012 FD 2012-05-09 VO 14 IS 3 SP 241 OP 256 K1 medicinal mushrooms K1 Antrodia camphorata K1 medicinal value K1 anti-hypertensive K1 anti-inflammatory K1 anti-oxidant K1 anti-tumor K1 immuno-modulatory activities K1 hepatoprotection K1 dietary supplements AB Antrodia camphorata is an extremely rare fungus native to the forested regions of Taiwan. It is also a traditional Chinese medicine, and Taiwanese aborigines applied it for treating liver diseases and protecting from food and drug intoxication. Scientific studies have demonstrated that A. camphorata crude extracts and pure compounds possess a variety of beneficial functions, such as anti-hypertensive, anti-hyperlipidemic, anti-inflammatory, anti-oxidant, anti-tumor, and immuno-modulatory activities. Recent studies have shown that many of these biological and pharmacological activities can be attributed to various active constituents, including polysaccharides, terpenoids, steroids, lignans, benzoquinone derivatives, benzenoids, and maleic and succinic acid derivatives. A. camphorata has been considered as a novel phytotherapeutic agent. However, detailed mechanistic studies or even clinical trials on A. camphorata are still rare. With the help of modern analytical techniques, it is not surprising that many novel constituents are being identified or fractionated from A. camphorata mycelium and fruiting bodies. This review summarizes the latest published results from A. camphorata research, focusing on the biological and pharmacological activities of the crude extract and known constituents of A. camphorata. PB Begell House LK https://www.dl.begellhouse.com/journals/708ae68d64b17c52,129584461de3f84f,6570b94e72937811.html