Journal of Environmental Pathology, Toxicology and Oncology
Erscheint 4 Ausgaben pro Jahr
ISSN Druckformat: 0731-8898
ISSN Online: 2162-6537
IF:
2.4
5-Year IF:
2.8
Immediacy Index:
0.5
Eigenfactor:
0.00049
JCI:
0.59
SJR:
0.429
SNIP:
0.507
CiteScore™::
3.9
H-Index:
49
Indexed in
Molecular Mechanisms of UVA-Induced Melanoma
Volumen 36,
Ausgabe 3, 2017,
pp. 217-228
DOI: 10.1615/JEnvironPatholToxicolOncol.2017020213
ABSTRAKT
Cutaneous melanoma is a deadly skin cancer, resulting from malignant transformation of melanocytes. Long-wave ultraviolet radiation (315−400 nm) is able to damage DNA, cause mutations, and induce melanoma. However, the exact mechanisms of UVA-induced cutaneous melanoma remain a matter of debate. In this review, we give a brief characterization of the most important elements in the photobiology of UVA in melanomagenesis.
SCHLÜSSELWÖRTER: cutaneous melanoma, melanomagenesis, solar radiation, UVA, DNA damage, CPD, oxidative stress,
DNA repair
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