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Journal of Environmental Pathology, Toxicology and Oncology
Impact-faktor: 1.625 5-jähriger Impact-Faktor: 1.63 SJR: 0.402 SNIP: 0.613 CiteScore™: 2.3

ISSN Druckformat: 0731-8898
ISSN Online: 2162-6537

Journal of Environmental Pathology, Toxicology and Oncology

DOI: 10.1615/JEnvironPatholToxicolOncol.v30.i3.90
pages 261-271

Photodynamic Inactivation of Microbial Pathogens: Disinfection of Water and Prevention of Water-Borne Diseases

Giulio Jori
Department of Biology, University of Padova, Via Ugo Bassi 58B, 35121 Padova, Italy
Michela Magaraggia
Department of Biology, University of Padova, Padova, Italy
Clara Fabris
Department of Biology, University of Padova, Padova, Italy
Marina Soncin
Department of Biology, University of Padova, Padova, Italy
Monica Camerin
Department of Biology, University of Padova, Padova, Italy
Laura Tallandini
Department of Biology, University of Padova, Padova, Italy
Olimpia Coppellotti
Department of Biology, University of Padova, Padova, Italy
70 papers in international journals; 80 communications at international congresses; 1 Laboratory Guide on Invertebrate Zoology; Italian edition of 4 texts of Zoology
Laura Guidolin
Department of Biology, University of Padova, Padova, Italy

ABSTRAKT

Porphyrins have been shown to act as very efficient photosensitizing agents against a broad number of microbial pathogens, including bacteria, fungi, and protozoa. This property has promising applications at a clinical level for the treatment of infectious diseases by photodynamic therapy. Moreover, this technique is also being used to address environmental problems of high significance, such as the decontamination of wastewaters, the disinfection of fish-farming tanks, the protection of animal species (e.g., amphibians and reptiles) that are endangered by pathogens whose life cycle takes place largely in aqueous media, and the control of populations of noxious insects. Such diversified applications take advantage of the availability of a truly large number of porphyrin derivatives with chemical structures that can be tailored to comply with the physical and chemical properties as well as the biological features of several milieus. In addition, the property typical of porphyrins to absorb essentially all of the wavelengths in the sun emission spectrum allows the promotion of processes largely based on natural resources with significant energy savings and low impact on ecosystems.


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