Erscheint 4 Ausgaben pro Jahr
ISSN Druckformat: 1050-6934
ISSN Online: 1940-4379
Indexed in
Longer-term Effects of Implanted Vagal Nerve Stimulation
ABSTRAKT
Vagal nerve stimulation (VNS) is a non-pharmacologic therapeutic intervention approved in adults and children with neuropsychiatric disorders. Studies conducted over the past 20 years have demonstrated that VNS results in immediate and longer-term changes in brain regions implicated in neuropsychiatric disorders, such as the thalamus, cerebellum, orbitofrontal cortex, limbic system, hypothalamus, and medulla with vagus innervations. This review summarizes the effects of longer-term implanted VNS and how the incorporation of this non-pharmacologic therapeutic management in the treatment regime can be beneficial to address the needs of patients who are unable to tolerate medications and/or undergo surgery and do not respond to pharmacologic therapies. We also highlight the therapeutic efficacy of longer-term implanted VNS, safety, tolerability, patient acceptance, adherence, and adverse events, if any, in adults and children in this modality of treatment.
-
Yuan Hsiangkuo, Silberstein Stephen D., Vagus Nerve and Vagus Nerve Stimulation, a Comprehensive Review: Part II, Headache: The Journal of Head and Face Pain, 56, 2, 2016. Crossref
-
Tsai Jeng-Dau, Chang Ying-Chao, Lin Lung-Chang, Hung Kun-Long, The neuropsychological outcome of pediatric patients with refractory epilepsy treated with VNS — A 24-month follow-up in Taiwan, Epilepsy & Behavior, 56, 2016. Crossref
-
Rossi Simone, Santarnecchi Emiliano, Valenza Gaetano, Ulivelli Monica, The heart side of brain neuromodulation, Philosophical Transactions of the Royal Society A: Mathematical, Physical and Engineering Sciences, 374, 2067, 2016. Crossref
-
Engineer Crystal T., Hays Seth A., Kilgard Michael P., Vagus nerve stimulation as a potential adjuvant to behavioral therapy for autism and other neurodevelopmental disorders, Journal of Neurodevelopmental Disorders, 9, 1, 2017. Crossref
-
Kuna Samuel T., Back to the Future or Forward to the Past?, Sleep, 34, 11, 2011. Crossref
-
Tsai Jeng-Dau, Yang Rei-Cheng, Chang Ming-Yuh, Fan Hueng-Chuen, Hung Kun-Long, TCNS V.N.S., Vagus nerve stimulation for patients with refractory epilepsy: Demographic features and neuropsychological outcomes of the VNS Taiwan child neurology society database, Epilepsy & Behavior, 111, 2020. Crossref
-
Chen Xuanzhao, Xu Li, Li Zeyan, Autonomic Neural Circuit and Intervention for Comorbidity Anxiety and Cardiovascular Disease, Frontiers in Physiology, 13, 2022. Crossref
-
Sirigu Angela, Desmurget Michel, Neuroscience: Boosting the brain, Current Biology, 31, 10, 2021. Crossref