Abo Bibliothek: Guest
Digitales Portal Digitale Bibliothek eBooks Zeitschriften Referenzen und Berichte Forschungssammlungen
Critical Reviews™ in Immunology
Impact-faktor: 1.404 5-jähriger Impact-Faktor: 3.347 SJR: 0.706 SNIP: 0.55 CiteScore™: 2.19

ISSN Druckformat: 1040-8401
ISSN Online: 2162-6472

Volumes:
Volumen 40, 2020 Volumen 39, 2019 Volumen 38, 2018 Volumen 37, 2017 Volumen 36, 2016 Volumen 35, 2015 Volumen 34, 2014 Volumen 33, 2013 Volumen 32, 2012 Volumen 31, 2011 Volumen 30, 2010 Volumen 29, 2009 Volumen 28, 2008 Volumen 27, 2007 Volumen 26, 2006 Volumen 25, 2005 Volumen 24, 2004 Volumen 23, 2003 Volumen 22, 2002 Volumen 21, 2001 Volumen 20, 2000 Volumen 19, 1999 Volumen 18, 1998 Volumen 17, 1997 Volumen 16, 1996 Volumen 15, 1995 Volumen 14, 1994

Critical Reviews™ in Immunology

DOI: 10.1615/CritRevImmunol.v21.i1-3.160
13 pages

A Unique Folate Hydrolase, Prostate-Specific Membrane Antigen (PSMA): A Target For Immunotherapy?

Jason Tasch
Department of Cancer Biology, Lerner Research Institute, Cleveland Clinic Foundation, 9500 Euclid Avenue, Cleveland, OH 44195
Mike Gong
Departments of Urology, Memorial Hospital, Memorial Sloan-Kettering Cancer Center, 1275 York Avenue, New York, NY 10021
Michel Sadelain
Department Human Genetics, Memorial Hospital, Memorial Sloan-Kettering Cancer Center, 1275 York Avenue, New York, NY 10021
Warren D. W. Heston
Department of Cancer Biology, Lerner Research Institute, Cleveland Clinic Foundation, 9500 Euclid Avenue, Cleveland, OH 44195

ABSTRAKT

Prostate-specific membrane antigen (PSMA) is a potential target in prostate cancer patients because it is very highly expressed and because it has been reported to be upregulated by androgen deprivation. This review discusses the historical background, biochemical characteristics, gene regulation, potential for targeting, tissue localization, and a novel T-body strategy.


Articles with similar content:

Targeting the Regulatory Machinery of BIM for Cancer Therapy
Critical Reviews™ in Eukaryotic Gene Expression, Vol.22, 2012, issue 2
Steven Grant, Hisashi Harada
Identifying Crosstalk between Raf Kinase Inhibitor Protein and Systemic Lupus Erythematosus
Critical Reviews™ in Immunology, Vol.39, 2019, issue 6
Inesa Navasardyan, Benjamin Bonavida
COMMENTARY. Regulation of Drug and Immune Resistance by YY1 in Cancer
Forum on Immunopathological Diseases and Therapeutics, Vol.1, 2010, issue 1-2
James A. McCubrey, Maria C. Mazzarino, Natale D'Alessandro
Role of Endogenous Nitric Oxide in Hyperaggressiveness of Tumor Cells that Survive a Photodynamic Therapy Challenge
Critical Reviews™ in Oncogenesis, Vol.21, 2016, issue 5-6
Albert W. Girotti
Targeted Molecular Therapeutic Options for Hepatocellular Carcinoma
Critical Reviews™ in Oncogenesis, Vol.25, 2020, issue 1
Latha Neerukonda, Bassam Ghabach, Ishna Sharma, Kalyani Narra, Swathi Sridhar, Riyaz Basha, Umesh T. Sankpal