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Critical Reviews™ in Oncogenesis
SJR: 0.631 SNIP: 0.503 CiteScore™: 2.2

ISSN Druckformat: 0893-9675
ISSN Online: 2162-6448

Critical Reviews™ in Oncogenesis

DOI: 10.1615/CritRevOncog.2014010866
pages 107-119

NK Cells and Virus-Related Cancers

Rabinarayan Mishra
Department of Pathology, University of Massachusetts Medical School, 368 Plantation Street, AS9-2051, Worcester, MA 01605
Raymond Welsh
Department of Pathology, University of Massachusetts Medical School, 368 Plantation Street, AS9-2051, Worcester, MA 01605
Eva Szomolanyi-Tsuda
Department of Pathology, University of Massachusetts Medical School, 368 Plantation Street, AS9-2051, Worcester, MA 01605

ABSTRAKT

Natural killer (NK) cells become activated during viral infections and can play roles in such infections by attacking virus-infected cells or by regulating adaptive immune responses. Experimental models suggest that NK cells may also have the capacity to restrain virus-induced cancers. Here, we discuss the seven viruses linked to human cancers and the evidence of NK cell involvement in these systems.

SCHLÜSSELWÖRTER: NK cells, virus, cancer

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