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ISSN Druckformat: 0893-9675
ISSN Online: 2162-6448
Indexed in
Dynamins and BAR Proteins−Safeguards against Cancer
ABSTRAKT
Dynamins and BAR proteins are crucial in a wide variety of cellular processes for their ability to mediate membrane remodeling, such as membrane curvature and membrane fission and fusion. In this review, we highlight dynamins and BAR proteins and the cellular mechanisms that are involved in the initiation and progression of cancer. We specifically discuss the roles of the seproteinsin endocytosis, endo-lysosomal trafficking, autophagy, and apoptosis as these processes are all tightly linked to membrane remodeling and cancer.
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Kong Leopold, Sochacki Kem A., Wang Huaibin, Fang Shunming, Canagarajah Bertram, Kehr Andrew D., Rice William J., Strub Marie-Paule, Taraska Justin W., Hinshaw Jenny E., Cryo-EM of the dynamin polymer assembled on lipid membrane, Nature, 560, 7717, 2018. Crossref
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Le Roux Anabel-Lise, Quiroga Xarxa, Walani Nikhil, Arroyo Marino, Roca-Cusachs Pere, The plasma membrane as a mechanochemical transducer, Philosophical Transactions of the Royal Society B: Biological Sciences, 374, 1779, 2019. Crossref