Abo Bibliothek: Guest
Digitales Portal Digitale Bibliothek eBooks Zeitschriften Referenzen und Berichte Forschungssammlungen
Heat Transfer Research
Impact-faktor: 0.404 5-jähriger Impact-Faktor: 0.8 SJR: 0.264 SNIP: 0.504 CiteScore™: 0.88

ISSN Druckformat: 1064-2285
ISSN Online: 2162-6561

Volumen 50, 2019 Volumen 49, 2018 Volumen 48, 2017 Volumen 47, 2016 Volumen 46, 2015 Volumen 45, 2014 Volumen 44, 2013 Volumen 43, 2012 Volumen 42, 2011 Volumen 41, 2010 Volumen 40, 2009 Volumen 39, 2008 Volumen 38, 2007 Volumen 37, 2006 Volumen 36, 2005 Volumen 35, 2004 Volumen 34, 2003 Volumen 33, 2002 Volumen 32, 2001 Volumen 31, 2000 Volumen 30, 1999 Volumen 29, 1998 Volumen 28, 1997

Heat Transfer Research

DOI: 10.1615/HeatTransRes.2012006425
pages 345-388


Amir Yousef Sajjadi
Department of Mechanical and Aerospace Engineering, Florida Institute of Technology, Melbourne, FL 32901, USA
Kunal Mitra
Department of Biomedical Engineering Florida Institute of Technology 150 W University Blvd, Melbourne, FL, USA
Zhixiong Guo
Department of Mechanical and Aerospace Engineering, Rutgers, the State University of New Jersey, New Brunswick, NJ, USA


Studying the interaction of ultrashort pulse lasers with biological tissues and the corresponding mathematical modeling of possible thermal damage is of fundamental importance to the understanding of laser-tissue interaction for advancing surgical application of lasers. The objective of this paper is to review the existing techniques for thermal analysis of laser-tissue interaction, focusing on temperature rise and plasma-mediated ablation. Different laser-tissue interaction mechanisms are discussed, and the existing techniques for characterization of extent of damage are presented. A novel approach of using a focused laser beam from an ultrashort pulse laser source to ablate the subcutaneous tumors with minimal thermal effects is introduced. The extent of laser-induced damage is studied by determining the space-time expression patterns of heat shock proteins.