Abo Bibliothek: Guest
Digitales Portal Digitale Bibliothek eBooks Zeitschriften Referenzen und Berichte Forschungssammlungen
Critical Reviews™ in Biomedical Engineering
SJR: 0.207 SNIP: 0.376 CiteScore™: 0.79

ISSN Druckformat: 0278-940X
ISSN Online: 1943-619X

Volumen 47, 2019 Volumen 46, 2018 Volumen 45, 2017 Volumen 44, 2016 Volumen 43, 2015 Volumen 42, 2014 Volumen 41, 2013 Volumen 40, 2012 Volumen 39, 2011 Volumen 38, 2010 Volumen 37, 2009 Volumen 36, 2008 Volumen 35, 2007 Volumen 34, 2006 Volumen 33, 2005 Volumen 32, 2004 Volumen 31, 2003 Volumen 30, 2002 Volumen 29, 2001 Volumen 28, 2000 Volumen 27, 1999 Volumen 26, 1998 Volumen 25, 1997 Volumen 24, 1996 Volumen 23, 1995

Critical Reviews™ in Biomedical Engineering

DOI: 10.1615/CritRevBiomedEng.v30.i456.70
pages 419-457

Advances in Gastrointestinal Electrical Stimulation

Zhiyue Lin
Department of Medicine, University of Kansas Medical Center, Kansas City, Kansas
J. D. Z. Chen
Division of Gastroenterology, University of Texas Medical Branch, Galveston, Texas


Electrical stimulation of the gastrointestinal (GI) tract, analogous to pacing the human heart, is an attractive idea. This is because these organs, like the heart, have their own natural pacemakers, and the electrical signals they generate can be altered by externally delivering certain types of electric currents via intraluminal or serosal electrodes to certain areas of the GI tract. A number of studies on animals have been accomplished successfully to treat a variety of disease models, including gastroparesis, dumping, and short bowel syndrome. Over the past 10 years or so, electrical stimulation of the GI tract has received increasing attention among researchers and clinicians because of new techniques, such as implantable devices, and promising results achieved in treatment of gastroparesis and morbid obesity. The objective of this article is to review the advances in electrical stimulation of the gastrointestinal tract. First the electrophysiology of the GI tract and history of GI electrical stimulation are introduced. Then various methods of electrical stimulation of the stomach and small bowel in healthy animals and models of GI diseases are reviewed. Finally clinical applications of electrical stimulation to GI disorders and their possible mechanisms are discussed.

Articles with similar content:

Developments in Gastrointestinal Electrical Stimulation
Critical Reviews™ in Biomedical Engineering, Vol.45, 2017, issue 1-6
Zhiyue Lin, J. D. Z. Chen
Biopolymers as Transdermal Drug Delivery Systems in Dermatology Therapy
Critical Reviews™ in Therapeutic Drug Carrier Systems, Vol.27, 2010, issue 2
M.A. Navya, K. H. Basavaraj, Siddaramaiah, George Johnsy, R. Rashmi
Gastroretentive Floating Drug-Delivery Systems: A Critical Review
Critical Reviews™ in Therapeutic Drug Carrier Systems, Vol.28, 2011, issue 1
Udaya Kotreka, Moji Christianah Adeyeye
Clinical Applications of lontophoretic Devices in Rehabilitation Medicine
Critical Reviews™ in Physical and Rehabilitation Medicine, Vol.10, 1998, issue 2
Peter C. Panus, Ajay K. Banga
Comprehensive Review on Magnetic Resonance Imaging in Alzheimer's Disease
Critical Reviews™ in Biomedical Engineering, Vol.44, 2016, issue 3
Olga Dona, Cheryl Druchok, Jeff Thompson