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Critical Reviews™ in Biomedical Engineering

Erscheint 6 Ausgaben pro Jahr

ISSN Druckformat: 0278-940X

ISSN Online: 1943-619X

SJR: 0.262 SNIP: 0.372 CiteScore™:: 2.2 H-Index: 56

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Absorbable Mesh Aids in Development of Discrete, Tissue-Engineered Constructs

Volumen 28, Ausgabe 3&4, 2000, pp. 383-387
DOI: 10.1615/CritRevBiomedEng.v28.i34.60
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ABSTRAKT

Absorbable mesh was investigated as a potential containment material in which to house discrete, small, tissue-engineered constructs. The mesh was fashioned into bags of varying shapes and consistent volumes. Cells were cultivated on porous, collagen beads, and the tissue constructs were placed into the bags. The mechanical integrity of the bags and feasibility of the design was tested in vitro. The bags successfully maintained their integrity as the cells developed on the collagen matrices. Furthermore, their porosity allowed access of nutrients and waste products to and from the developing tissue. Having demonstrated feasibility of processing, the next step is to optimize the cell culture specifications and materials design.

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