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Plasma Medicine
SJR: 0.198 SNIP: 0.183 CiteScore™: 0.57

ISSN Druckformat: 1947-5764
ISSN Online: 1947-5772

Plasma Medicine

DOI: 10.1615/PlasmaMed.2014009711
pages 45-55

Effects of Atmosphere Composition and Liquid Type on Plasma-Generated Reactive Species in Biologically Relevant Solutions

Helena Tresp
Centre for Innovation Competence plasmatis, Greifswald; Leibniz Institute for Plasma Science and Technology INP Greifswald e.V., Greifswald, Germany
Malte U. Hammer
Centre for Innovation Competence plasmatis, Greifswald, Germany; Leibniz Institute for Plasma Science and Technology INP Greifswald e.V., Greifswald, Germany
Klaus-Dieter Weltmann
Leibniz-Institute for Plasma Science and Technology (INP Greifswald), ZIK Plasmatis, Greifswald, Germany
Stephan Reuter
Center for Innovation Competence plasmatis, Greifswald, Germany; Leibniz Institute for Plasma Science and Technology, Greifswald, Germany

ABSTRAKT

This study investigates the reactive species generation by an atmospheric pressure argon plasma jet in biologically relevant liquids. The plasma jet is shielded from the atmosphere by different mixtures of oxygen and nitrogen gas. Different liquids with increasing complexity in ingredient composition (namely, sodium chloride solution, Dulbecco's phosphate-buffered saline solution, and Roswell Park Memorial Institute cell culture medium) were plasma treated and the formation of reactive species was studied. By varying the shielding gas composition, the type and quantity of generated reactive species, reactive nitrogen species, or reactive oxygen species can be tailored. This study shows that the ingredients of the plasma-treated liquid strongly influence the reactive species formation.


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