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Computational Thermal Sciences: An International Journal
ESCI SJR: 0.249 SNIP: 0.434 CiteScore™: 1.4

ISSN Druckformat: 1940-2503
ISSN Online: 1940-2554

Computational Thermal Sciences: An International Journal

DOI: 10.1615/ComputThermalScien.2016015252
pages 459-465

A MODELING STUDY TO ANALYZE THERMAL AND MECHANICAL EFFECTS OF PULSED LASER IRRADIATION ON TISSUES

Mohit Ganguly
Department of Biomedical Engineering, Vanderbilt University, Nashville, TN, USA; Department of Biomedical Engineering, Florida Institute of Technology, Melbourne, FL, USA
Kunal Mitra
Department of Biomedical Engineering Florida Institute of Technology 150 W University Blvd, Melbourne, FL, USA

ABSTRAKT

Pulsed lasers are known for their spatial and temporal specificity in delivering heat energy to the tissues. This is useful in the laser ablation treatment mechanism where damage to the healthy tissues is highly undesired. Pulsed laser irradiation on tissues leads to photothermal and photomechanical interactions, which result in damage to the irradiated zone. Cumulative effects of photothermal and photomechanical interactions lead to damage in the tissues affecting the healthy surrounding tissues. In this paper, the effects of both mechanisms are studied using a finite-element model. A three-layered model of the skin is considered which is irradiated using a focused Nd:YAG infrared laser beam. The finite-element solver COMSOL Multiphysics is used to simulate the thermal and mechanical interaction due to the laser irradiation. Thermal effects of irradiation are evaluated using the equivalent thermal dose administered to the tissue. The mechanical interaction is evaluated in terms of the stress generated in the tissue during the laser ablation damage. Results obtained are useful in characterizing the laser parameters such as repetition rate, laser power, and pulse width affecting the ablation process. This will enable optimizing the laser ablation process for a more effective treatment with minimum damage to surrounding tissues.


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