Abo Bibliothek: Guest
Critical Reviews™ in Eukaryotic Gene Expression

Erscheint 6 Ausgaben pro Jahr

ISSN Druckformat: 1045-4403

ISSN Online: 2162-6502

The Impact Factor measures the average number of citations received in a particular year by papers published in the journal during the two preceding years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) IF: 1.6 To calculate the five year Impact Factor, citations are counted in 2017 to the previous five years and divided by the source items published in the previous five years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) 5-Year IF: 2.2 The Immediacy Index is the average number of times an article is cited in the year it is published. The journal Immediacy Index indicates how quickly articles in a journal are cited. Immediacy Index: 0.3 The Eigenfactor score, developed by Jevin West and Carl Bergstrom at the University of Washington, is a rating of the total importance of a scientific journal. Journals are rated according to the number of incoming citations, with citations from highly ranked journals weighted to make a larger contribution to the eigenfactor than those from poorly ranked journals. Eigenfactor: 0.00058 The Journal Citation Indicator (JCI) is a single measurement of the field-normalized citation impact of journals in the Web of Science Core Collection across disciplines. The key words here are that the metric is normalized and cross-disciplinary. JCI: 0.33 SJR: 0.345 SNIP: 0.46 CiteScore™:: 2.5 H-Index: 67

Indexed in

Cell-Context Dependent TCF/LEF Expression and Function: Alternative Tales of Repression, De-Repression and Activation Potentials

Volumen 21, Ausgabe 3, 2011, pp. 207-236
DOI: 10.1615/CritRevEukarGeneExpr.v21.i3.10
Get accessGet access

ABSTRAKT

Wnt signaling controls cell specification and fate during development and adult tissue homeostasis by converging on a small family of DNA binding factors, the T-cell factor/lymphoid enhancer factor (TCF/LEF) family. In response to Wnt signals, TCF/LEF members undergo a transcriptional switch from repression to activation mediated in part by nuclear β-catenin binding and recruitment of co-activator complexes. In mammals, the specificity and fine tuning of this transcriptional switch is also achieved by the cell-context-dependent expression of four members (TCF7, TCF7L1, TCF7L2, and LEF1) and numerous variants, which display differential DNA binding affinity and specificity, repression strength, activation potential, and regulators. TCF7/LEF1 variants are generated by alternative promoters, alternative exon cassettes, and alternative donor/acceptor splicing sites, allowing combinatorial insertion/exclusion of modular functional and regulatory domains. In this review we present mounting evidence for the interdependency of TCF7/LEF1 variant expression and functions with cell lineage and cell state. We also illustrate how the p53 and nuclear receptor family of transcription factors, known to control cell fate and to inhibit Wnt signaling, may participate in the fine tuning of TCF7/LEF1 repression/activation potentials.

REFERENZIERT VON
  1. Jin Guoliang, Mizutani Akifumi, Fukuda Takayuki, Otani Takayuki, Yan Ting, Prieto Vila Marta, Murakami Hiroshi, Kudoh Takayuki, Hirohata Satoshi, Kasai Tomonari, Salomon David S., Seno Masaharu, Eosinophil cationic protein enhances stabilization of β-catenin during cardiomyocyte differentiation in P19CL6 embryonal carcinoma cells, Molecular Biology Reports, 40, 4, 2013. Crossref

  2. Mabbott Neil A, Baillie J, Brown Helen, Freeman Tom C, Hume David A, An expression atlas of human primary cells: inference of gene function from coexpression networks, BMC Genomics, 14, 1, 2013. Crossref

  3. Takamoto Iseki, Kubota Naoto, Nakaya Keizo, Kumagai Katsuyoshi, Hashimoto Shinji, Kubota Tetsuya, Inoue Mariko, Kajiwara Eiji, Katsuyama Hisayuki, Obata Atsushi, Sakurai Yoshitaka, Iwamoto Masahiko, Kitamura Tadahiro, Ueki Kohjiro, Kadowaki Takashi, TCF7L2 in mouse pancreatic beta cells plays a crucial role in glucose homeostasis by regulating beta cell mass, Diabetologia, 57, 3, 2014. Crossref

  4. Yu Li, Guan Yingjun, Wu Xin, Chen Yanchun, Liu Zhijun, Du Hongmei, Wang Xin, Wnt Signaling is Altered by Spinal Cord Neuronal Dysfunction in Amyotrophic Lateral Sclerosis Transgenic Mice, Neurochemical Research, 38, 9, 2013. Crossref

  5. Abellán Antonio, Desfilis Ester, Medina Loreta, Combinatorial expression of Lef1, Lhx2, Lhx5, Lhx9, Lmo3, Lmo4, and Prox1 helps to identify comparable subdivisions in the developing hippocampal formation of mouse and chicken, Frontiers in Neuroanatomy, 8, 2014. Crossref

  6. Gibbs Daniel J, Coates Juliet C, AtMYB93is an endodermis-specific transcriptional regulator of lateral root development in arabidopsis, Plant Signaling & Behavior, 9, 10, 2014. Crossref

  7. Wu P, Shi K J, An J J, Ci Y L, Li F, Hui K Y, Yang Y, Xu C M, The LEF1/CYLD axis and cIAPs regulate RIP1 deubiquitination and trigger apoptosis in selenite-treated colorectal cancer cells, Cell Death & Disease, 5, 2, 2014. Crossref

  8. Hoppler Stefan, Waterman Marian L., Evolutionary Diversification of Vertebrate TCF/LEF Structure, Function, and Regulation, in Wnt Signaling in Development and Disease, 2014. Crossref

  9. Han Wenxiao, Wang Hongying, Regulation of canonical Wnt/β-catenin pathway in the nucleus, Chinese Science Bulletin, 59, 28, 2014. Crossref

  10. Gibbs Daniel J, Coates Juliet C, AtMYB93 is an endodermis-specific transcriptional regulator of lateral root development in Arabidopsis, Plant Signaling & Behavior, 9, 7, 2014. Crossref

  11. Luque Maria Carolina, Santos Camila C., Mairena Eliane C., Wilkinson Peter, Boucher Genèvieve, Segurado Aluisio C., Fonseca Luiz A., Sabino Ester, Kalil Jorge E., Cunha-Neto Edecio, Gene expression profile in long-term non progressor HIV infected patients: In search of potential resistance factors, Molecular Immunology, 62, 1, 2014. Crossref

  12. Chatterjee Sujash S., Saj Abil, Gocha Tenzin, Murphy Matthew, Gonsalves Foster C., Zhang Xiaoqian, Hayward Penelope, Akgöl Oksuz Betül, Shen Steven S., Madar Aviv, Martinez Arias Alfonso, DasGupta Ramanuj, Inhibition of β-catenin–TCF1 interaction delays differentiation of mouse embryonic stem cells, Journal of Cell Biology, 211, 1, 2015. Crossref

  13. Shen Huali, Zhong Fan, Zhang Yang, Yu Hongxiu, Liu Yinkun, Qin Lunxiu, He Fuchu, Tang Zhaoyou, Yang Pengyuan, Transcriptome and proteome of human hepatocellular carcinoma reveal shared metastatic pathways with significant genes, PROTEOMICS, 15, 11, 2015. Crossref

  14. Nakano Naoko, Kato Mitsuyasu, Itoh Susumu, Regulation of the TMEPAI promoter by TCF7L2: the C-terminal tail of TCF7L2 is essential to activate theTMEPAIgene, Journal of Biochemistry, 159, 1, 2016. Crossref

  15. LI XIAOFEI, CHEN YONGXIN, WU SHUANG, HE JINKE, LOU LIANQING, YE WEIWEI, WANG JINHE, microRNA-34a and microRNA-34c promote the activation of human hepatic stellate cells by targeting peroxisome proliferator-activated receptor γ, Molecular Medicine Reports, 11, 2, 2015. Crossref

  16. Kalantari Roya, Chiang Cheng-Ming, Corey David R., Regulation of mammalian transcription and splicing by Nuclear RNAi, Nucleic Acids Research, 44, 2, 2016. Crossref

  17. Shah Meera, Rennoll Sherri A, Raup-Konsavage Wesley M, Yochum Gregory S, A dynamic exchange of TCF3 and TCF4 transcription factors controls MYC expression in colorectal cancer cells, Cell Cycle, 14, 3, 2015. Crossref

  18. Singh Surendra, Arcaroli John, Chen Ying, Thompson David C., Messersmith Wells, Jimeno Antonio, Vasiliou Vasilis, Tsonis Panagiotis A, ALDH1B1 Is Crucial for Colon Tumorigenesis by Modulating Wnt/β-Catenin, Notch and PI3K/Akt Signaling Pathways, PLOS ONE, 10, 5, 2015. Crossref

  19. Masuda Takamasa, Ishitani Tohru, Context-dependent regulation of the β-catenin transcriptional complex supports diverse functions of Wnt/β-catenin signaling, Journal of Biochemistry, 161, 1, 2017. Crossref

  20. Pujadas G., Cervantes S., Tutusaus A., Ejarque M., Sanchez L., García A., Esteban Y., Fargas L., Alsina B., Hartmann C., Gomis R., Gasa R., Wnt9a deficiency discloses a repressive role of Tcf7l2 on endocrine differentiation in the embryonic pancreas, Scientific Reports, 6, 1, 2016. Crossref

  21. Domingues Mélanie J., Martinez-Sanz Juan, Papon Laura, Larue Lionel, Mouawad Liliane, Bonaventure Jacky, Klymkowsky Michael, Structure-based mutational analysis of ICAT residues mediating negative regulation of β-catenin co-transcriptional activity, PLOS ONE, 12, 3, 2017. Crossref

  22. Hrdličková Radmila, Nehyba Jiří, Bargmann William, Bose Henry R., Mari Bernard, Multiple Tumor Suppressor microRNAs Regulate Telomerase and TCF7, an Important Transcriptional Regulator of the Wnt Pathway, PLoS ONE, 9, 2, 2014. Crossref

  23. Koval Michael, Junctional Interplay in Lung Epithelial Barrier Function, in Lung Epithelial Biology in the Pathogenesis of Pulmonary Disease, 2017. Crossref

  24. Majchrzak Kinga, Nelson Michelle H., Bowers Jacob S., Bailey Stefanie R., Wyatt Megan M., Wrangle John M., Rubinstein Mark P., Varela Juan C., Li Zihai, Himes Richard A., Chan Sherine S.L., Paulos Chrystal M., β-catenin and PI3Kδ inhibition expands precursor Th17 cells with heightened stemness and antitumor activity, JCI Insight, 2, 8, 2017. Crossref

  25. Gaillard Dany, Bowles Spencer G., Salcedo Ernesto, Xu Mingang, Millar Sarah E., Barlow Linda A., Copenhaver Gregory P., β-catenin is required for taste bud cell renewal and behavioral taste perception in adult mice, PLOS Genetics, 13, 8, 2017. Crossref

  26. Zhang Mingfeng, Lykke-Andersen Soren, Zhu Bin, Xiao Wenming, Hoskins Jason W, Zhang Xijun, Rost Lauren M, Collins Irene, Bunt Martijn van de, Jia Jinping, Parikh Hemang, Zhang Tongwu, Song Lei, Jermusyk Ashley, Chung Charles C, Zhu Bin, Zhou Weiyin, Matters Gail L, Kurtz Robert C, Yeager Meredith, Jensen Torben Heick, Brown Kevin M, Ongen Halit, Bamlet William R, Murray Bradley A, McCarthy Mark I, Chanock Stephen J, Chatterjee Nilanjan, Wolpin Brian M, Smith Jill P, Olson Sara H, Petersen Gloria M, Shi Jianxin, Amundadottir Laufey, Characterising cis-regulatory variation in the transcriptome of histologically normal and tumour-derived pancreatic tissues, Gut, 67, 3, 2018. Crossref

  27. Sierra Robert A., Hoverter Nathan P., Ramirez Ricardo N., Vuong Linh M., Mortazavi Ali, Merrill Bradley J., Waterman Marian L., Donovan Peter J., TCF7L1 suppresses primitive streak gene expression to support human embryonic stem cell pluripotency, Development, 2018. Crossref

  28. Vonbrüll Matthias, Riegel Elisabeth, Halter Christian, Aigner Michaela, Bock Holger, Werner Birgit, Lindhorst Thomas, Czerny Thomas, A Dominant Negative Antisense Approach Targeting β-Catenin, Molecular Biotechnology, 60, 5, 2018. Crossref

  29. Law William D., Fogarty Elizabeth A., Vester Aimée, Antonellis Anthony, A genome-wide assessment of conserved SNP alleles reveals a panel of regulatory SNPs relevant to the peripheral nerve, BMC Genomics, 19, 1, 2018. Crossref

  30. Gaillard Dany, Shechtman Lauren A., Millar Sarah E., Barlow Linda A., Fractionated head and neck irradiation impacts taste progenitors, differentiated taste cells, and Wnt/β-catenin signaling in adult mice, Scientific Reports, 9, 1, 2019. Crossref

  31. Dräger Julia, Simon-Keller Katja, Pukrop Tobias, Klemm Florian, Wilting Jörg, Sticht Carsten, Dittmann Kai, Schulz Matthias, Leuschner Ivo, Marx Alexander, Hahn Heidi, LEF1 reduces tumor progression and induces myodifferentiation in a subset of rhabdomyosarcoma, Oncotarget, 8, 2, 2017. Crossref

  32. Birdwell Christine E., Prasai Kanchanjunga, Dykes Samantha, Jia Yali, Munroe Tawsha G.C., Bienkowska-Haba Malgorzata, Scott Rona S., Epstein-Barr virus stably confers an invasive phenotype to epithelial cells through reprogramming of the WNT pathway, Oncotarget, 9, 12, 2018. Crossref

  33. Mayer Claus-Dieter, Magon de La Giclais Soizick, Alsehly Fozan, Hoppler Stefan, Diverse LEF/TCF Expression in Human Colorectal Cancer Correlates with Altered Wnt-Regulated Transcriptome in a Meta-Analysis of Patient Biopsies, Genes, 11, 5, 2020. Crossref

  34. Nouri Parivash, Götz Sebastian, Rauser Benedict, Irmler Martin, Peng Changgeng, Trümbach Dietrich, Kempny Christian, Lechermeier Carina G., Bryniok Agnes, Dlugos Andrea, Euchner Ellen, Beckers Johannes, Brodski Claude, Klümper Claudia, Wurst Wolfgang, Prakash Nilima, Dose-Dependent and Subset-Specific Regulation of Midbrain Dopaminergic Neuron Differentiation by LEF1-Mediated WNT1/b-Catenin Signaling, Frontiers in Cell and Developmental Biology, 8, 2020. Crossref

  35. Beineke Philip, Fitch Karen, Tao Heng, Elashoff Michael R, Rosenberg Steven, Kraus William E, Wingrove James A, A whole blood gene expression-based signature for smoking status, BMC Medical Genomics, 5, 1, 2012. Crossref

  36. Pillai Viju Vijayan, Koganti Prasanthi P., Kei Tiffany G., Gurung Shailesh, Butler W. Ronald, Selvaraj Vimal, Efficient induction and sustenance of pluripotent stem cells from bovine somatic cells, Biology Open, 10, 10, 2021. Crossref

  37. Fu Haiying, Zhou Huarong, Qiu Yanyan, Wang Jianfei, Ma Zhiming, Li Hongping, Zhang Feng, Qiu Chenxi, Shen Jianzhen, Liu Tingbo, SEPT6_TRIM33 Gene Fusion and Mutated TP53 Pathway Associate With Unfavorable Prognosis in Patients With B-Cell Lymphomas, Frontiers in Oncology, 11, 2021. Crossref

  38. Gui Yujuan, Grzyb Kamil, Thomas Mélanie H., Ohnmacht Jochen, Garcia Pierre, Buttini Manuel, Skupin Alexander, Sauter Thomas, Sinkkonen Lasse, Single-nuclei chromatin profiling of ventral midbrain reveals cell identity transcription factors and cell-type-specific gene regulatory variation, Epigenetics & Chromatin, 14, 1, 2021. Crossref

  39. Skopelitou Diamanto, Miao Beiping, Srivastava Aayushi, Kumar Abhishek, Kuświk Magdalena, Dymerska Dagmara, Paramasivam Nagarajan, Schlesner Matthias, Lubinski Jan, Hemminki Kari, Försti Asta, Bandapalli Obul, Whole Exome Sequencing Identifies APCDD1 and HDAC5 Genes as Potentially Cancer Predisposing in Familial Colorectal Cancer, International Journal of Molecular Sciences, 22, 4, 2021. Crossref

  40. Ni Min, Chen Yiwen, Fei Teng, Li Dan, Lim Elgene, Liu X. Shirley, Brown Myles, Amplitude modulation of androgen signaling by c-MYC, Genes & Development, 27, 7, 2013. Crossref

  41. Escuin-Ordinas Helena, Liu Yining, Sun Lu, Hugo Willy, Dimatteo Robert, Huang Rong Rong, Krystofinski Paige, Azhdam Ariel, Lee Jordan, Comin-Anduix Begoña, Cochran Alistair J., Lo Roger S., Segura Tatiana, Scumpia Philip O., Ribas Antoni, Chen Suzie, Wound healing with topical BRAF inhibitor therapy in a diabetic model suggests tissue regenerative effects, PLOS ONE, 16, 6, 2021. Crossref

  42. Galli Carlo, Macaluso Guido, Passeri Giovanni, Serotonin: a novel bone mass controller may have implications for alveolar bone, Journal of Negative Results in BioMedicine, 12, 1, 2013. Crossref

  43. Yeh Hsi-Yi, Liu Bing-Hsien, Sieber Martin, Hsu Shan-hui, Substrate-dependent gene regulation of self-assembled human MSC spheroids on chitosan membranes, BMC Genomics, 15, 1, 2014. Crossref

  44. Company Verónica, Moreno-Cerdá Ana, Andreu-Cervera Abraham, Murcia-Ramón Raquel, Almagro-García Francisca, Echevarría Diego, Martínez Salvador, Puelles Eduardo, Wnt1 Role in the Development of the Habenula and the Fasciculus Retroflexus, Frontiers in Cell and Developmental Biology, 9, 2021. Crossref

  45. Pedersen Elisabeth A., Menon Rajasree, Bailey Kelly M., Thomas Dafydd G., Van Noord Raelene A., Tran Jenny, Wang Hongwei, Qu Ping Ping, Hoering Antje, Fearon Eric R., Chugh Rashmi, Lawlor Elizabeth R., Activation of Wnt/β-Catenin in Ewing Sarcoma Cells Antagonizes EWS/ETS Function and Promotes Phenotypic Transition to More Metastatic Cell States, Cancer Research, 76, 17, 2016. Crossref

  46. del Bosque-Plata Laura, Martínez-Martínez Eduardo, Espinoza-Camacho Miguel Ángel, Gragnoli Claudia, The Role of TCF7L2 in Type 2 Diabetes, Diabetes, 70, 6, 2021. Crossref

  47. Heuberger Julian, Kosel Frauke, Qi Jingjing, Grossmann Katja S., Rajewsky Klaus, Birchmeier Walter, Shp2/MAPK signaling controls goblet/paneth cell fate decisions in the intestine, Proceedings of the National Academy of Sciences, 111, 9, 2014. Crossref

  48. Fingleton Barbara, Making Cancer Quiescent: SPDEF De-Cycles Beta-Catenin, Gastroenterology, 153, 1, 2017. Crossref

  49. Osei-Sarfo Kwame, Gudas Lorraine J., Retinoic Acid Suppresses the Canonical Wnt Signaling Pathway in Embryonic Stem Cells and Activates the Noncanonical Wnt Signaling Pathway, Stem Cells, 32, 8, 2014. Crossref

  50. Torres‐Aguila Nuria P., Salonna Marika, Hoppler Stefan, Ferrier David E. K., Evolutionary diversification of the canonical Wnt signaling effector TCF/LEF in chordates, Development, Growth & Differentiation, 64, 3, 2022. Crossref

  51. Verma Manu, Loh Nellie Y., Sabaratnam Rugivan, Vasan Senthil K., van Dam Andrea D., Todorčević Marijana, Neville Matthew J., Toledo Enrique, Karpe Fredrik, Christodoulides Constantinos, TCF7L2 plays a complex role in human adipose progenitor biology, which might contribute to genetic susceptibility to type 2 diabetes, Metabolism, 133, 2022. Crossref

  52. Sun Jianchao, Hong Junmin, Sun Siguo, Wang Xiaofei, Peng Yan, Zhou Jie, Huang Yingjie, Li Shuangxing, Chen Weijian, Li Chunhai, Xu Kang, Ye Wei, Transcription factor 7-like 2 controls matrix degradation through nuclear factor κB signaling and is repressed by microRNA-155 in nucleus pulposus cells, Biomedicine & Pharmacotherapy, 108, 2018. Crossref

Zukünftige Artikel

PRMT6 promotes the immune evasion of gastric cancer via upregulating ANXA1 Liang Xu, Fenger Zhang, Binqi Yu, Shengnan Jia, Sunfu Fan PURPL promotes M2 macrophage polarization in lung cancer via regulating RBM4/xCT signaling Jipeng Guo, Chongwen Gong, Hao Wang SIAH1 promotes the pyroptosis of cardiomyocytes in diabetic cardiomyopathy via regulating IκB-α/NF-κB signaling Jinbin Wu, Yaoming Yan SLC7A2-mediated lysine catabolism inhibits immunosuppression in triple negative breast cancer Yuanyuan Sun, Yaqing Li, Chengying Jiang, Chenying Liu, Yuanming Song SIAH2-mediated degradation of ACSL4 inhibits the anti-tumor activity of CD8+ T cells in hepatocellular carcinoma Fangzheng Shu, Yuhua Shi, Xiangxiang Shan, Wenzhang Zha, Rengen Fan, Wanjiang Xue RBM15-mediated N6-methyl adenosine (m6A) modification of EZH2 drives the epithelial-mesenchymal transition of cervical cancer Ruixue Wang, Wenhua Tan Evidence-Based Storytelling and A Strategic Roadmap to Promote Cancer Prevention Via Adolescent HPV Vaccination in Northern New England Matthew Dugan, Gary Stein, Jan Carney, Sheila Clifford-Bova KDM4A-AS1 promotes cell proliferation, migration and invasion via the miR-4306/STX6 axis in hepatocellular carcinoma Wei Cao, Yuhan Ren, Ying Liu, Guoshu Cao, Zhen Chen, Fan Wang HDAC1-mediated downregulation of NEU1 exacerbates the aggressiveness of cervical cancer Nanzi Xie, Sisi Mei, Changlan Dai, Wei Chen Effect of miR-26b-5p on progression of acute myeloid leukemia by regulating USP48-mediated Wnt/β-catenin pathway Yu Xie, Lin Tan, Kun Wu, Deyun Li, Chengping Li
Digitales Portal Digitale Bibliothek eBooks Zeitschriften Referenzen und Berichte Forschungssammlungen Preise und Aborichtlinien Begell House Kontakt Language English 中文 Русский Português German French Spain