Abo Bibliothek: Guest
Critical Reviews™ in Eukaryotic Gene Expression

Erscheint 6 Ausgaben pro Jahr

ISSN Druckformat: 1045-4403

ISSN Online: 2162-6502

The Impact Factor measures the average number of citations received in a particular year by papers published in the journal during the two preceding years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) IF: 1.6 To calculate the five year Impact Factor, citations are counted in 2017 to the previous five years and divided by the source items published in the previous five years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) 5-Year IF: 2.2 The Immediacy Index is the average number of times an article is cited in the year it is published. The journal Immediacy Index indicates how quickly articles in a journal are cited. Immediacy Index: 0.3 The Eigenfactor score, developed by Jevin West and Carl Bergstrom at the University of Washington, is a rating of the total importance of a scientific journal. Journals are rated according to the number of incoming citations, with citations from highly ranked journals weighted to make a larger contribution to the eigenfactor than those from poorly ranked journals. Eigenfactor: 0.00058 The Journal Citation Indicator (JCI) is a single measurement of the field-normalized citation impact of journals in the Web of Science Core Collection across disciplines. The key words here are that the metric is normalized and cross-disciplinary. JCI: 0.33 SJR: 0.345 SNIP: 0.46 CiteScore™:: 2.5 H-Index: 67

Indexed in

Protein Kinase C Control of Gene Expression

Volumen 11, Ausgabe 1-3, 2001, 26 pages
DOI: 10.1615/CritRevEukarGeneExpr.v11.i1-3.120
Get accessGet access

ABSTRAKT

Gene expression is fashioned at multiple interconnected levels and is controlled by a complex interplay between nucleosomal assembly, the establishment of multifaceted transcriptional motifs, and the temporal and spatial organization of chromatin in loops and domains. Protein phosphorylation is one of the most versatile posttranslational modifications used in eukaryotic cells and plays a crucial role in the continuous remodeling of different transcriptional regulators. The protein kinase C (PKC) family of serine-threonine kinases encompasses 12 different isozymes that have been shown to transduce a myriad of signals mediated by phospholipid hydrolysis as a consequence of the activation of G protein-coupled receptors, tyrosine kinase receptors, and nonreceptor tyrosine kinases. Although the analysis of PKC activity in many systems has provided crucial insights to its biological function, unraveling the molecular mechanisms that underlie isozyme-specific modulation of gene expression within the complexity of genome structure and function remains a challenging issue. This review focuses on recent advances in PKC-dependent regulation of gene expression within the context of the dynamic linkages involving nuclear architecture and transcription. Implications of isozyme-specific phosphorylation of selected members of transcription factors are also discussed. Future perspectives disclosed by recently available methods for large-scale transcriptional profiling are also outlined.

REFERENZIERT VON
  1. Ding Yu-Qiang, Xiang Chuan-Xi, Chen Zhou-Feng, Generation and characterization of the PKCγ-Cre mouse line, genesis, 43, 1, 2005. Crossref

  2. Chin Khew-Voon, Selvanayagam Zachariah E., Vittal Ragini, Kita Tsunekazu, Kudoh Kazuya, Yang Chung S., Wong Yick Fu, Cheung Tak Hong, Yeo Winnie, Chung Tony Kwok Hung, Lin Yong, Liao Jason, Shih Joe Weichung, Yap Sook Fan, Lin Albert W., Application of expression genomics in drug development and genomic medicine, Drug Development Research, 62, 2, 2004. Crossref

  3. Zheng Zhen-Yu, Li Qing-Zhang, Chen Da-Yuan, Schatten Heide, Sun Qing-Yuan, Translocation of phospho-protein kinase Cs implies their roles in meiotic-spindle organization, polar-body emission and nuclear activity in mouse eggs, Reproduction, 129, 2, 2005. Crossref

  4. Prete Salvatore Pasquale, Rossi Lorena, Correale Pier Paolo, Turriziani Mario, Baier Susanne, Tamburrelli Giuliana, De Vecchis Liana, Bonmassar Enzo, Aquino Angelo, Combined effects of protein kinase inhibitors and 5-fluorouracil on CEA expression in human colon cancer cells, Pharmacological Research, 52, 2, 2005. Crossref

  5. Kulinsky V. I., Kolesnichenko L. S., Molecular Mechanisms of Hormonal Activity. II. Kinase Systems. Systems with Intracellular Receptors. Transactivation of STS, Biochemistry (Moscow), 70, 4, 2005. Crossref

  6. Kis Bela, Rajapakse Nishadi C., Snipes James A., Nagy Krisztina, Horiguchi Takashi, Busija David W., Diazoxide induces delayed pre-conditioning in cultured rat cortical neurons, Journal of Neurochemistry, 87, 4, 2004. Crossref

  7. Hara Yuko, Kusumi Yoshiaki, Mitsumata Masako, Li Xiao-Kang, Fujino Masayuki, Lysophosphatidylcholine upregulates LOX-1, chemokine receptors, and activation-related transcription factors in human T-cell line Jurkat, Journal of Thrombosis and Thrombolysis, 26, 2, 2008. Crossref

  8. Facchini Annalisa, Borzì Rosa Maria, Flamigni Flavio, Induction of ornithine decarboxylase in T/C-28a2 chondrocytes by lysophosphatidic acid: Signaling pathway and inhibition of cell proliferation, FEBS Letters, 579, 13, 2005. Crossref

  9. Traber Maret G., Atkinson Jeffrey, Vitamin E, antioxidant and nothing more, Free Radical Biology and Medicine, 43, 1, 2007. Crossref

  10. Glesne David, Vogt Stefan, Maser Jorg, Legnini Daniel, Huberman Eliezer, Regulatory properties and cellular redistribution of zinc during macrophage differentiation of human leukemia cells, Journal of Structural Biology, 155, 1, 2006. Crossref

  11. Nakai M., Ito J., Kashiwazaki N., Men N.T., Tanihara F., Noguchi J., Kaneko H., Onishi A., Kikuchi K., Treatment with protein kinase C activator is effective for improvement of male pronucleus formation and further embryonic development of sperm-injected oocytes in pigs, Theriogenology, 85, 4, 2016. Crossref

  12. Weeber Edwin J., Caldwell Kevin K., Delay fear conditioning modifies phospholipase C-β1a signaling in the hippocampus and frontal cortex, Pharmacology Biochemistry and Behavior, 78, 1, 2004. Crossref

  13. McNamara Robert K., Ostrander Michelle, Abplanalp William, Richtand Neil M., Benoit Stephen C., Clegg Debbie J., Modulation of phosphoinositide–protein kinase C signal transduction by omega-3 fatty acids: Implications for the pathophysiology and treatment of recurrent neuropsychiatric illness, Prostaglandins, Leukotrienes and Essential Fatty Acids, 75, 4-5, 2006. Crossref

  14. Oh Young-Il, Kim Jong-Hoon, Kang Chang-Won, Oxidative stress in MCF-7 cells is involved in the effects of retinoic acid-induced activation of protein kinase C-δ on insulin-like growth factor-I secretion and synthesis, Growth Hormone & IGF Research, 20, 2, 2010. Crossref

  15. Scharf Matthew T., Naidoo Nirinjini, Zimmerman John E., Pack Allan I., The energy hypothesis of sleep revisited, Progress in Neurobiology, 86, 3, 2008. Crossref

  16. Devappa Rakshit K., Malakar Chandi C., Makkar Harinder P.S., Becker Klaus, Pharmaceutical potential of phorbol esters fromJatropha curcasoil, Natural Product Research, 27, 16, 2013. Crossref

  17. Purkayastha Sudarshana, Fernando Suraj Shawn, Diallo Souleymane, Cohen Leah, Ranasinghe Buddima, Levano Kelly, Banerjee Probal, Regulation of protein kinase C isozymes during early postnatal hippocampal development, Brain Research, 1288, 2009. Crossref

  18. Stricklett Peter K., Strait Kevin A., Kohan Donald E., Novel Regulation of Endothelin-1 Promoter Activity by Protein Kinase C, Cell Biochemistry and Biophysics, 61, 3, 2011. Crossref

  19. Chamias Rachel, Huleihel Mahmoud, Aboud Mordechai, The mechanism of HTLV-1 LTR activation by TPA varies in different human T-cell lines: Role of specific PKC isoforms, Leukemia Research, 34, 1, 2010. Crossref

  20. Siflinger-Birnboim Alma, Johnson Arnold, Protein kinase C modulates pulmonary endothelial permeability: a paradigm for acute lung injury, American Journal of Physiology-Lung Cellular and Molecular Physiology, 284, 3, 2003. Crossref

  21. Broccardo Carolyn J., Billings Ruth E., Andersen Melvin E., Hanneman William H., Probing the Control Elements of the CYP1A1 Switching Module in H4IIE Hepatoma Cells, Toxicological Sciences, 88, 1, 2005. Crossref

  22. Hezareh Marjan, Moukil Moulay Ahmed, Szanto Ildiko, Pondarzewski Malgorzata, Mouche Sarah, Cherix Nathalie, Brown Stephen J, Carpentier Jean-Louis, Foti Michelangelo, Mechanisms of HIV Receptor and Co-Receptor Down-Regulation by Prostratin: Role of Conventional and Novel PKC Isoforms, Antiviral Chemistry and Chemotherapy, 15, 4, 2004. Crossref

  23. Chiarini Anna, Whitfield James F., Armato Ubaldo, Dal Pra Ilaria, Protein Kinase C-βII Is an Apoptotic Lamin Kinase in Polyomavirus-transformed, Etoposide-treated pyF111 Rat Fibroblasts, Journal of Biological Chemistry, 277, 21, 2002. Crossref

  24. Hempstead Andrew D., Isberg Ralph R., Host Signal Transduction and Protein Kinases Implicated in Legionella Infection, in Molecular Mechanisms in Legionella Pathogenesis, 376, 2013. Crossref

  25. Thomas Joseph, Morris Pierre, Seigel Eric, Vitamin D, Testosterone, Epigenetics and Pain an Evolving Concept of Neurosignaling, Neuroplasticity and Homeostasis, World Journal of Neuroscience, 08, 02, 2018. Crossref

  26. Brose Nils, Rosenmund Christian, Move over protein kinase C, you've got company: alternative cellular effectors of diacylglycerol and phorbol esters, Journal of Cell Science, 115, 23, 2002. Crossref

  27. Kumar Vikas, Jong Yuh-Jiin I., O'Malley Karen L., Activated Nuclear Metabotropic Glutamate Receptor mGlu5 Couples to Nuclear Gq/11 Proteins to Generate Inositol 1,4,5-Trisphosphate-mediated Nuclear Ca2+ Release, Journal of Biological Chemistry, 283, 20, 2008. Crossref

  28. O'Malley Karen L., Jong Yuh-Jiin I., Gonchar Yuri, Burkhalter Andreas, Romano Carmelo, Activation of Metabotropic Glutamate Receptor mGlu5 on Nuclear Membranes Mediates Intranuclear Ca2+ Changes in Heterologous Cell Types and Neurons, Journal of Biological Chemistry, 278, 30, 2003. Crossref

  29. Kambhampati Suman, Li Yongzhong, Verma Amit, Sassano Antonella, Majchrzak Beata, Deb Dilip K., Parmar Simrit, Giafis Nick, Kalvakolanu Dhananjaya V., Rahman Arshad, Uddin Shahab, Minucci Saverio, Tallman Martin S., Fish Eleanor N., Platanias Leonidas C., Activation of Protein Kinase Cδ by All-trans-retinoic Acid, Journal of Biological Chemistry, 278, 35, 2003. Crossref

Zukünftige Artikel

PRMT6 promotes the immune evasion of gastric cancer via upregulating ANXA1 Liang Xu, Fenger Zhang, Binqi Yu, Shengnan Jia, Sunfu Fan PURPL promotes M2 macrophage polarization in lung cancer via regulating RBM4/xCT signaling Jipeng Guo, Chongwen Gong, Hao Wang SIAH1 promotes the pyroptosis of cardiomyocytes in diabetic cardiomyopathy via regulating IκB-α/NF-κB signaling Jinbin Wu, Yaoming Yan SLC7A2-mediated lysine catabolism inhibits immunosuppression in triple negative breast cancer Yuanyuan Sun, Yaqing Li, Chengying Jiang, Chenying Liu, Yuanming Song SIAH2-mediated degradation of ACSL4 inhibits the anti-tumor activity of CD8+ T cells in hepatocellular carcinoma Fangzheng Shu, Yuhua Shi, Xiangxiang Shan, Wenzhang Zha, Rengen Fan, Wanjiang Xue RBM15-mediated N6-methyl adenosine (m6A) modification of EZH2 drives the epithelial-mesenchymal transition of cervical cancer Ruixue Wang, Wenhua Tan Evidence-Based Storytelling and A Strategic Roadmap to Promote Cancer Prevention Via Adolescent HPV Vaccination in Northern New England Matthew Dugan, Gary Stein, Jan Carney, Sheila Clifford-Bova KDM4A-AS1 promotes cell proliferation, migration and invasion via the miR-4306/STX6 axis in hepatocellular carcinoma Wei Cao, Yuhan Ren, Ying Liu, Guoshu Cao, Zhen Chen, Fan Wang HDAC1-mediated downregulation of NEU1 exacerbates the aggressiveness of cervical cancer Nanzi Xie, Sisi Mei, Changlan Dai, Wei Chen Effect of miR-26b-5p on progression of acute myeloid leukemia by regulating USP48-mediated Wnt/β-catenin pathway Yu Xie, Lin Tan, Kun Wu, Deyun Li, Chengping Li
Digitales Portal Digitale Bibliothek eBooks Zeitschriften Referenzen und Berichte Forschungssammlungen Preise und Aborichtlinien Begell House Kontakt Language English 中文 Русский Português German French Spain