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Critical Reviews™ in Eukaryotic Gene Expression

Erscheint 6 Ausgaben pro Jahr

ISSN Druckformat: 1045-4403

ISSN Online: 2162-6502

The Impact Factor measures the average number of citations received in a particular year by papers published in the journal during the two preceding years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) IF: 1.6 To calculate the five year Impact Factor, citations are counted in 2017 to the previous five years and divided by the source items published in the previous five years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) 5-Year IF: 2.2 The Immediacy Index is the average number of times an article is cited in the year it is published. The journal Immediacy Index indicates how quickly articles in a journal are cited. Immediacy Index: 0.3 The Eigenfactor score, developed by Jevin West and Carl Bergstrom at the University of Washington, is a rating of the total importance of a scientific journal. Journals are rated according to the number of incoming citations, with citations from highly ranked journals weighted to make a larger contribution to the eigenfactor than those from poorly ranked journals. Eigenfactor: 0.00058 The Journal Citation Indicator (JCI) is a single measurement of the field-normalized citation impact of journals in the Web of Science Core Collection across disciplines. The key words here are that the metric is normalized and cross-disciplinary. JCI: 0.33 SJR: 0.345 SNIP: 0.46 CiteScore™:: 2.5 H-Index: 67

Indexed in

Factors Influencing the Amino Acid and Peptide Transporter Proteins mRNA Expression in Avian Species

Volumen 26, Ausgabe 4, 2016, pp. 343-352
DOI: 10.1615/CritRevEukaryotGeneExpr.2016016279
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ABSTRAKT

The commercial strains of broiler chickens have genetically selected to reach market weight at younger ages. In order to sustain increased growth rate requires an efficient assimilation of nutrients from the intestinal lumen, which is permitted through nutrient assimilation through the enterocytes that is facilitated by many nutrient transporter proteins. These trans-membrane proteins have specific action, well known kinetics and assist in the partitioning of nutrients among tissues. Amino acids are transported across the plasma membrane as free amino acids or short chain peptides through several independent systems encoded by various nutrient transporter gene products, and these systems may act on multiple substrates. Any deficiency in amino acid and peptide transportation results in metabolic disorders, illustrating crucial roles being played by the body's ability to maintain amino acid homeostasis. The ability of tissues to adapt to changes in input of amino acids related to numerous external factors that negatively affect amino acids utilization appears to result from responses that alter nutrient transporter protein mRNA expression mandated for to maintain amino acid and protein homeostasis. This review summarizes the results of some recently published scientific articles on the effects of different factors that influence intestinal amino acid and peptide transporter proteins mRNA expressions in domestic fowl. Understanding the regulatory effects of diet on amino acid and peptide transport systems in tissues offers insight that ostensibly will help nutritionists to improve the efficiency of dietary protein utilization in poultry.

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