ISSN Druckformat: 2155-014X
Archives: Volume 1, 2010 to Volume 9, 2018
Volumes:Volumen 9, 2018 Volumen 8, 2017 Volumen 7, 2016 Volumen 6, 2015 Volumen 5, 2014 Volumen 4, 2013 Volumen 3, 2012 Volumen 2, 2011 Volumen 1, 2010
International Journal of Physiology and Pathophysiology
Effects of Deltaran and Melatonin on Immune System in Rats in Experimental Contact Dermatitis
Oleksii O. Shandra
"Odessa National Medical University"
We investigated the activity of humoral and cellular links of immunity and leukocyte functional stability indicators in rats with experimental contact dermatitis (ECD) under pharmacological correction by application of deltaran and melatonin. Chronic experiments were performed on the model of chrome-induced ECD. Complex pharmacological correction of humoral and cellular links of immunity and leukocyte stability was assessed using separate and combined administrations of deltaran and melatonin. The results have shown the pronounced disturbances in humoral and cellular links of immunity, as well as neutrophil and lymphocyte functional stability under chrome-induced ECD in rats. Violations of the functional activity of the immune system were corrected by applications of deltaran and melatonin. The activity of the therapeutic complex had exponential character.
SCHLÜSSELWÖRTER: experimental contact dermatitis, immune reactivity, neutrophil alteration index, lymphocyte alteration index, deltaran, melatonin, pharmacological correction
|Digitales Portal||Digitale Bibliothek||eBooks||Zeitschriften||Referenzen und Berichte||Forschungssammlungen|