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International Journal of Medicinal Mushrooms
Impact-faktor: 1.423 5-jähriger Impact-Faktor: 1.525 SJR: 0.431 SNIP: 0.661 CiteScore™: 1.38

ISSN Druckformat: 1521-9437
ISSN Online: 1940-4344

Volumes:
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International Journal of Medicinal Mushrooms

DOI: 10.1615/IntJMedMushrooms.2019032896
pages 1051-1063

Characterization of Biological Activities of Methanol Extract of Fuscoporia torulosa (Basidiomycetes) from Italy

Stefano Covino
Department of Chemistry, Biology and Biotechnology, University of Perugia, 06122 Perugia (PG), Italy
Eleonora D'Ellena
Department of Chemistry, Biology and Biotechnology, University of Perugia, 06122 Perugia (PG), Italy
Bruno Tirillini
Department of Biomolecular Sciences, University of Urbino, Urbino, Italy
Giancarlo Angeles
Department of Chemistry, Biology and Biotechnology, University of Perugia, 06122 Perugia (PG), Italy
Andrea Arcangeli
Department of Chemistry, Biology and Biotechnology, University of Perugia, 06122 Perugia (PG), Italy
Giancarlo Bistocchi
Department of Chemistry, Biology and Biotechnology, University of Perugia, 06122 Perugia (PG), Italy
Roberto Venanzoni
Department of Chemistry, Biology and Biotechnology, University of Perugia, 06122 Perugia (PG), Italy
Paola Angelini
Department of Chemistry, Biology and Biotechnology, University of Perugia, 06122 Perugia (PG), Italy

ABSTRAKT

This work investigated the antiradical, antibacterial, and antifungal properties of a methanol extract from Fuscoporia torulosa (PeruMyc1834) fruit body from Central Italy. The ITS partial sequence of the F. torulosa strain matched at a 100% rate those of various strains belonging to the species. Two complementary test systems, namely α,α-diphenyl-β-picrylhydrazyl (DPPH) radical scavenging and β-carotene/linoleic acid systems, were used. Free radical scavenging, measured by DPPH assay on methanol extract, showed an activity of 38.17 ± 2.74% of Trolox activity. The methanol extract of F. torulosa inhibited the growth of Gram-positive bacteria, particularly those belonging to the genus Bacillus (i.e., B. subtilis and B. cereus), better than Gram-negative bacteria. All the fungal isolates used in the present study for antifungal activity inhibited their growth when a concentration of 2.27 mg mL-1 of methanol extract was used (minimum inhibitory concentration from < 0.28 to 2.27 mg mL-1). This study established that the extracted antioxidant and antimicrobial compounds produced by F. torulosa can be exploited in treating diseases that affect humans, plants, and animals. There is a need to carry out further study to establish the chemical composition of the methanol extract.

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