Abo Bibliothek: Guest
Digitales Portal Digitale Bibliothek eBooks Zeitschriften Referenzen und Berichte Forschungssammlungen
International Journal of Medicinal Mushrooms
Impact-faktor: 1.423 5-jähriger Impact-Faktor: 1.525 SJR: 0.431 SNIP: 0.661 CiteScore™: 1.38

ISSN Druckformat: 1521-9437
ISSN Online: 1940-4344

Volumes:
Volumen 21, 2019 Volumen 20, 2018 Volumen 19, 2017 Volumen 18, 2016 Volumen 17, 2015 Volumen 16, 2014 Volumen 15, 2013 Volumen 14, 2012 Volumen 13, 2011 Volumen 12, 2010 Volumen 11, 2009 Volumen 10, 2008 Volumen 9, 2007 Volumen 8, 2006 Volumen 7, 2005 Volumen 6, 2004 Volumen 5, 2003 Volumen 4, 2002 Volumen 3, 2001 Volumen 2, 2000 Volumen 1, 1999

International Journal of Medicinal Mushrooms

DOI: 10.1615/IntJMedMushrooms.v16.i5.70
pages 485-495

A Comparative Study of the Antimicrobial, Antioxidant, and Cytotoxic Activities of Methanol Extracts from Fruit Bodies and Fermented Mycelia of Caterpillar Medicinal Mushroom Cordyceps militaris (Ascomycetes)

Caihong Dong
State Key Laboratory of Mycology, Institute of Microbiology, Chinese Academy of Sciences, Beijing, China
Tao Yang
State Key Laboratory of Mycology, Institute of Microbiology, Chinese Academy of Sciences, Beijing, 100101, China; University of Chinese Academy of Sciences, Beijing, 100049, China
Tiantian Lian
College of Land and Environment, Shenyang Agricultural University, Shenyang, 110866, China; State Key Laboratory of Mycology, Institute of Microbiology, Chinese Academy of Sciences, Beijing, 100101, China

ABSTRAKT

Cordyceps militaris is one of the most popular mushrooms and nutraceuticals in Eastern Asia. This study assayed and compared the antimicrobial, antioxidant, and cytotoxic properties of the methanol extracts from fruiting bodies and fermented mycelia of C. militaris, as well as the contents of total phenol, flavonoids, and cordycepin. The results showed that the extracts from fruiting bodies possessed broad antimicrobial activities against all microorganisms tested (both bacteria and fungi), whereas that from the fermented mycelia showed selective activity. The antioxidant potential of two extracts is significant in the four tested systems in vitro, including total antioxidant capacity, scavenging abilities on 1,1-diphenyl-2-picrylhydrazyl (DPPH·) radicals, reducing power, and chelating ability on ferrous ions. The fruiting bodies had stronger DPPH· radical scavenging activity, whereas the fermented mycelia had stronger total antioxidant capacity, chelating ability, and reducing power, which suggested that they had their own role and worked in different ways. Both extracts present strong activities against tumor cell line A549. The results obtained indicated that extracts from C. militaris might be valuable antimicrobial, antioxidant, and cytotoxic natural sources and seemed to be applicable in health and medicine as well as in the food industry.


Articles with similar content:

Comparison of Antioxidant and Antiproliferation Activities of Polysaccharides from Eight Species of Medicinal Mushrooms
International Journal of Medicinal Mushrooms, Vol.17, 2015, issue 3
Yangyang Yong, Yifan Gu, Zeliang Wang, Shizhu Zhang, Peiying Chen, Ling Lu
Antioxidant, Anti-Inflammatory, and Antitumor Activities of Cultured Mycelia and Fruiting Bodies of the Elm Oyster Mushroom, Hypsizygus ulmarius (Agaricomycetes)
International Journal of Medicinal Mushrooms, Vol.18, 2016, issue 3
Kainoor K. Janardhanan, Korattuvalappil S. Ravikumar, Karattuthodi Fathimathu Zuhara, Panavalappil Greeshma, Mangalathmelathil N. Neethu, Meera Pandey
The Effect of Growth Substrate and Extraction Solvent on Biological Activities of Oyster Culinary Medicinal Mushroom Pleurotus ostreatus (Agaricomycetes)
International Journal of Medicinal Mushrooms, Vol.20, 2018, issue 10
Daniel Fernando Cortez Acosta, Gerardo Rafael Hernández Carbajal, Tannia Alexandra Quiñones Muñoz, Nohely Salas Navarrete, Érica Esthela Córdova Gurrola, Elizabeth del Carmen Varela Santos
Effects of Various Treatments on Extraction of the Main Bioactive Components and Determination of Biological Activity of Extracts from the Caterpillar Medicinal Mushroom Cordyceps militaris (Ascomycetes)
International Journal of Medicinal Mushrooms, Vol.20, 2018, issue 9
Chaomin Yin, Hong Gao, Xiuzhi Fan, Defang Shi, Zhe Fan
Antioxidant and Antigenotoxicity Activities of Extracts from Liquid Submerged Culture of Culinary-Medicinal Ferula Oyster Mushroom, Pleurotus eryngii (DC.) Quél. var. ferulae (Lanzi) Sacc. (Agaricomycetideae)
International Journal of Medicinal Mushrooms, Vol.11, 2009, issue 4
Shu-Ling Hsieh, Juang-Lin Lien, Jinn-Chyi Wang, Shu-Hui Hu, Sue-Joan Chang