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International Journal of Medicinal Mushrooms

Erscheint 12 Ausgaben pro Jahr

ISSN Druckformat: 1521-9437

ISSN Online: 1940-4344

The Impact Factor measures the average number of citations received in a particular year by papers published in the journal during the two preceding years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) IF: 1.2 To calculate the five year Impact Factor, citations are counted in 2017 to the previous five years and divided by the source items published in the previous five years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) 5-Year IF: 1.4 The Immediacy Index is the average number of times an article is cited in the year it is published. The journal Immediacy Index indicates how quickly articles in a journal are cited. Immediacy Index: 0.3 The Eigenfactor score, developed by Jevin West and Carl Bergstrom at the University of Washington, is a rating of the total importance of a scientific journal. Journals are rated according to the number of incoming citations, with citations from highly ranked journals weighted to make a larger contribution to the eigenfactor than those from poorly ranked journals. Eigenfactor: 0.00066 The Journal Citation Indicator (JCI) is a single measurement of the field-normalized citation impact of journals in the Web of Science Core Collection across disciplines. The key words here are that the metric is normalized and cross-disciplinary. JCI: 0.34 SJR: 0.274 SNIP: 0.41 CiteScore™:: 2.8 H-Index: 37

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Combined Administration of the White Button Mushroom Agaricus bisporus (Agaricomycetes) and Lactobacillus casei Modulated Immune-Related Gene Expression and Mucosal and Serum Immune Parameters in a Goldfish (Carassius auratus) Model

Volumen 21, Ausgabe 5, 2019, pp. 503-513
DOI: 10.1615/IntJMedMushrooms.2019029551
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ABSTRAKT

The aim of this study was to evaluate the effects of white button mushroom (Agaricus bisporus) powder (MP) and Lactobacillus casei, administered either alone or together, on tnf-alpha messenger RNA levels and mucosal and serum immune parameters in goldfish (Carassius auratus). Goldfish (n = 180) were purchased and randomly allocated into 4 groups repeated in triplicate. An 8-week feeding trial was designed and included various treatments: basal diet (control); diet containing 107 colony-forming units [CFU]·g-1 L. casei (Pro); diet containing 1% A. bisporus powder (MP); and diet containing 107 CFU·g-1 L. casei + 1% A. bisporus powder (MP + Pro). The results revealed that combined administration of MP and Pro significantly (P < 0.05) improved expression of tnf-alpha 1 and tnf-alpha 2 genes, total immunoglobulin (Ig) level in the skin mucus, and protease and lysozyme activities in the goldfish. Similarly, serum lysozyme and serum alternative complement activity (ACH50) in goldfish fed MP + Pro was remarkably higher than that in the other groups (P < 0.05). With regard to total serum Ig levels, however, the difference was not significant between the goldfish fed MP + Pro and those receiving the other diets (P > 0.05). The highest expression of immune-related genes (tnf-alpha 1 and tnf-alpha 2), total Ig level in skin mucus, protease and lysozyme activity, and serum ACH50 and lysozyme activity were observed in goldfish fed MP + Pro. These findings reveal that A. bisporus with L. casei can be considered as a promising immunostimulant when administered in the diet in goldfish culture.

REFERENZIERT VON
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