Erscheint 12 Ausgaben pro Jahr
ISSN Druckformat: 1521-9437
ISSN Online: 1940-4344
Indexed in
Antioxidant Potential of Lingzhi or Reishi Medicinal Mushroom, Ganoderma lucidum (Higher Basidiomycetes) Cultivated on Artocarpus heterophyllus Sawdust Substrate in India
ABSTRAKT
The artificial cultivation of Ganoderma lucidum (MTCC1039) using Artocarpus heterophyllus as sawdust substrate was optimized and free radical scavenging activities of the generated fruiting bodies were investigated. The choice of A. heterophyllus as substrate was due to its easy availability in South India. Sawdust supplemented with dextrose medium yielded better spawn hyphae and early fruiting body initiation (15 days). The biological yield obtained was 42.06 ± 2.14 g/packet and the biological efficiency was 8.41 ± 0.48%. Both aqueous and methanolic extracts of fruiting body were analyzed for radical scavenging activity. Methanolic extract showed maximum scavenging activity for 1,1-diphenyl-2-picrylhydrazyl (IC50 = 290 μg/ml) and 2,2'-azino-bis(3-ethylbenzothiazoline- 6-sulphonic acid (IC50 = 580 μg/ml), whereas aqueous extract had better scavenging for ferric reducing antioxidant power (IC50 = 5 μg/ml). Total phenolic content and total antioxidant capacity were significantly higher in methanolic extract (p < 0.01). A positive correlation existed between the phenolic content and antioxidant activity. Our results indicated that fruiting bodies of G. lucidum cultivated in sawdust medium possess antioxidant property, which can be exploited for therapeutic application.
-
Wang Jue, Cao Bin, Zhao Haiping, Feng Juan, Emerging Roles of Ganoderma Lucidum in Anti-Aging, Aging and disease, 8, 6, 2017. Crossref
-
Shedoeva Aleksandra, Leavesley David, Upton Zee, Fan Chen, Wound Healing and the Use of Medicinal Plants, Evidence-Based Complementary and Alternative Medicine, 2019, 2019. Crossref
-
Zhang Zhi, Sun Lei, Zhou Guoren, Xie Peng, Ye Jinjun, Sepia ink oligopeptide induces apoptosis and growth inhibition in human lung cancer cells, Oncotarget, 8, 14, 2017. Crossref
-
Wang Li, Li Jie-qing, Zhang Ji, Li Zhi-min, Liu Hong-gao, Wang Yuan-zhong, Traditional uses, chemical components and pharmacological activities of the genus Ganoderma P. Karst.: a review, RSC Advances, 10, 69, 2020. Crossref
-
Shaher Fahmi, Qiu Hongbin, Wang Shuqiu, Hu Yu, Wang Weiqun, Zhang Yu, Wei Yao, AL-ward Hisham, Abdulghani Mahfoudh A. M., Alenezi Sattam Khulaif, Baldi Salem, Zhou Shaobo, Associated Targets of the Antioxidant Cardioprotection of Ganoderma lucidum in Diabetic Cardiomyopathy by Using Open Targets Platform: A Systematic Review, BioMed Research International, 2020, 2020. Crossref
-
Dat Tran Do, Viet Nguyen Duc, My Phan Le Thao, Linh Nguyen Thi, Thanh Vuong Hoai, Linh Nguyen Thi Thuy, Ngan Nguyen Thi Kim, Linh Ngo Thi Thuy, Nam Hoang Minh, Phong Mai Thanh, Hieu Nguyen Huu, The Application of Ethanolic Ultrasonication to Ameliorate the Triterpenoid Content Extracted from Vietnamese Ganoderma lucidum with the Examination by Gas Chromatography , ChemistrySelect, 6, 10, 2021. Crossref
-
Kiss Attila, Grünvald Petra, Ladányi Márta, Papp Viktor, Papp István, Némedi Erzsébet, Mirmazloum Iman, Heat Treatment of Reishi Medicinal Mushroom (Ganoderma lingzhi) Basidiocarp Enhanced Its β-glucan Solubility, Antioxidant Capacity and Lactogenic Properties, Foods, 10, 9, 2021. Crossref
-
Mirończuk-Chodakowska Iwona, Kujawowicz Karolina, Witkowska Anna Maria, Beta-Glucans from Fungi: Biological and Health-Promoting Potential in the COVID-19 Pandemic Era, Nutrients, 13, 11, 2021. Crossref
-
Aslaminabad Ramin, Rahimianshahreza Negin, Hosseini Seyed Amirhossein, Armagan Güliz, Khan Ahmad Kashif, Özbolat Gülüzar, Ahmed Omar Saad, Mardi Azar Amir, Adili Ali, Dağcı Taner, Konyalıoğlu Sibel, Özgönül Ali Mert, Regulation of Nrf2 and Nrf2-related proteins by ganoderma lucidum ın hepatocellular carcinoma, Molecular Biology Reports, 49, 10, 2022. Crossref